Down Syndrome News and Research

Latest Down Syndrome News and Research

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Individuals with Down syndrome, the genetic condition caused by triplication of human chromosome 21, also known as trisomy 21, display a very high risk of hospitalization and mortality after developing lung infections.

2 Aug 2023

COVID-19 led to increased anxiety for families with children with neurodevelopmental conditions

A peer-reviewed study published in the Journal of Global Health analyzed data from more than 6,600 families with a child with a neurodevelopmental condition (NDC) - autism, attention-deficit/hyperactivity disorder, developmental language disorder, Down syndrome, Williams syndrome, and intellectual disability - from 70 countries, including the United States.

31 Jul 2023

Five-year survival of children with acute lymphatic leukemia continues to increase

The five-year survival of all children with acute lymphatic leukemia (ALL) has continued to increase to 94%. This is evident from a study of 800 Dutch children. Within the study, modified treatment protocols for four subgroups were examined.

17 Jul 2023

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

People with Down syndrome, the condition caused by an extra copy of chromosome 21, or trisomy 21, display chronic dysregulation of their immune system, which can contribute to high rates of autoimmune conditions and severe complications from respiratory infections.

17 Jul 2023

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population.

12 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Scientists uncover molecular mechanism contributing to defective heart development in Down syndrome

Infants born with Down syndrome, the genetic condition caused by an extra copy of chromosome 21, or trisomy 21, are highly predisposed to congenital heart defects.

21 Jun 2023

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Live parental infant-directed singing has positive impacts on infants' emotional regulation, validation of the parent's role, and affect attunement, as identified in a systematic review of 21 studies. Benefits are observed in typically developing infants born at full term.

21 Jun 2023

Research on the first-ever human pangenome reference helps better understand chromosome biology

Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference.

2 Jun 2023

AI algorithms for rare disease diagnosis ignore the genetic, morphological diversity of humans

Up to 40% of rare diseases show facial alterations that enable researchers to identify some pathologies and they can even help them to establish an early diagnosis.

10 May 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

Research examines the impact of the COVID-19 pandemic on people with intellectual disabilities in the Netherlands. It shows that the mortality risk from COVID-19 was higher in people with intellectual disabilities than in the general population, and overall mortality disparities were further exacerbated during the first 2 years of the pandemic.

18 Apr 2023

People with Down syndrome are living longer, but the health system still treats many as kids

It took Samantha Lesmeister's family four months to find a medical professional who could see that she was struggling with something more than her Down syndrome.

17 Apr 2023

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Researchers described the case report of an infant boy experiencing rebound MIS-C.

12 Apr 2023

Key memory receptor is localized to interneurons

A key receptor regulating memory formation has been localized to interneurons, according to a study with implications for drug development.

11 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Down Syndrome News and Research

Latest Down Syndrome News and Research

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

COVID-19 led to increased anxiety for families with children with neurodevelopmental conditions

Five-year survival of children with acute lymphatic leukemia continues to increase

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Scientists uncover molecular mechanism contributing to defective heart development in Down syndrome

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Research on the first-ever human pangenome reference helps better understand chromosome biology

AI algorithms for rare disease diagnosis ignore the genetic, morphological diversity of humans

Researchers shed light on the genetics behind facial changes in Down syndrome

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

People with Down syndrome are living longer, but the health system still treats many as kids

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Key memory receptor is localized to interneurons

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

New genetic animal model may inform potential therapeutic options for Down syndrome

Scientists identify the cause of leukemia in people with trisomy 21

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Down Syndrome News and Research

Latest Down Syndrome News and Research

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Newsletters you may be interested in