Down Syndrome News and Research

Latest Down Syndrome News and Research

States reconsider religious exemptions for vaccinations in child care

More than half the children who attend Munchkin Land Daycare near Billings, Montana, have special needs or compromised immune systems.

3 Nov 2023

Texas A&M researchers win NIH grant to study metabolism in people with Down syndrome

A team of researchers at the Texas A&M University School of Veterinary Medicine & Biomedical Sciences (VMBS) has received a grant from the National Institutes of Health (NIH) to research metabolism in people with Down syndrome.

17 Oct 2023

Medicaid plays critical role in the health and well-being of adults with Down syndrome

Life expectancy has increased substantially for people in the United States with Down syndrome, from a median age of 4 years old in the 1950s to 57 years old in 2019.

16 Oct 2023

Speech Accessibility Project needs more participants with Parkinson's

The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson's.

24 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Individuals with Down syndrome, the genetic condition caused by triplication of human chromosome 21, also known as trisomy 21, display a very high risk of hospitalization and mortality after developing lung infections.

2 Aug 2023

COVID-19 led to increased anxiety for families with children with neurodevelopmental conditions

A peer-reviewed study published in the Journal of Global Health analyzed data from more than 6,600 families with a child with a neurodevelopmental condition (NDC)-;autism, attention-deficit/hyperactivity disorder, developmental language disorder, Down syndrome, Williams syndrome, and intellectual disability-;from 70 countries, including the United States.

31 Jul 2023

Five-year survival of children with acute lymphatic leukemia continues to increase

The five-year survival of all children with acute lymphatic leukemia (ALL) has continued to increase to 94%. This is evident from a study of 800 Dutch children. Within the study, modified treatment protocols for four subgroups were examined.

17 Jul 2023

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

People with Down syndrome, the condition caused by an extra copy of chromosome 21, or trisomy 21, display chronic dysregulation of their immune system, which can contribute to high rates of autoimmune conditions and severe complications from respiratory infections.

17 Jul 2023

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population.

12 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Scientists uncover molecular mechanism contributing to defective heart development in Down syndrome

Infants born with Down syndrome, the genetic condition caused by an extra copy of chromosome 21, or trisomy 21, are highly predisposed to congenital heart defects.

21 Jun 2023

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Live parental infant-directed singing has positive impacts on infants' emotional regulation, validation of the parent's role, and affect attunement, as identified in a systematic review of 21 studies. Benefits are observed in typically developing infants born at full term.

21 Jun 2023

Research on the first-ever human pangenome reference helps better understand chromosome biology

Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference.

2 Jun 2023

AI algorithms for rare disease diagnosis ignore the genetic, morphological diversity of humans

Up to 40% of rare diseases show facial alterations that enable researchers to identify some pathologies and they can even help them to establish an early diagnosis.

10 May 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

Research examines the impact of the COVID-19 pandemic on people with intellectual disabilities in the Netherlands. It shows that the mortality risk from COVID-19 was higher in people with intellectual disabilities than in the general population, and overall mortality disparities were further exacerbated during the first 2 years of the pandemic.

18 Apr 2023

People with Down syndrome are living longer, but the health system still treats many as kids

It took Samantha Lesmeister's family four months to find a medical professional who could see that she was struggling with something more than her Down syndrome.

17 Apr 2023

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Researchers described the case report of an infant boy experiencing rebound MIS-C.

12 Apr 2023

Down Syndrome News and Research

Latest Down Syndrome News and Research

States reconsider religious exemptions for vaccinations in child care

Texas A&M researchers win NIH grant to study metabolism in people with Down syndrome

Medicaid plays critical role in the health and well-being of adults with Down syndrome

Speech Accessibility Project needs more participants with Parkinson's

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

COVID-19 led to increased anxiety for families with children with neurodevelopmental conditions

Five-year survival of children with acute lymphatic leukemia continues to increase

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Scientists uncover molecular mechanism contributing to defective heart development in Down syndrome

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Research on the first-ever human pangenome reference helps better understand chromosome biology

AI algorithms for rare disease diagnosis ignore the genetic, morphological diversity of humans

Researchers shed light on the genetics behind facial changes in Down syndrome

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

COVID-19's hidden toll: Study reveals greater mortality disparities for people with intellectual disabilities

People with Down syndrome are living longer, but the health system still treats many as kids

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Down Syndrome News and Research

Latest Down Syndrome News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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