Down Syndrome News and Research

Latest Down Syndrome News and Research

UCI MIND secures major funding for new Alzheimer's research facility

With a $50 million lead gift from the Quilter family and approximately $30 million in new commitments, the University of California, Irvine's Institute for Memory Impairments and Neurological Disorders will begin planning to build a state-of-the-art research and care facility to enhance its position as a global leader in Alzheimer's disease and related dementias research and patient care.

8 Dec 2025

New discovery could reshape how scientists think about Alzheimer’s treatment

Rutgers neuroscientist Peng Jiang was visiting his hometown of Qianshan, a city in China's Anhui province, when a neighbor came to his parents' house with a story that would stay with him.

24 Nov 2025

UC Davis researchers lead $5.5 million study on language development in children with Down syndrome

UC Davis researchers are leading a $5.5 million study to better understand how children with Down syndrome develop expressive communication - the skills used to share what we want, think or feel.

21 Nov 2025

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

HMGN1 gene linked to heart problems in people with Down syndrome

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life.

22 Oct 2025

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule essential for the development and function of the nervous system, new research suggests.

17 Oct 2025

Study links high neuroinflammation in young people with Down Syndrome to Alzheimer's risk

Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the University of São Paulo (USP) in Brazil identified high levels of neuroinflammation in young individuals with Down syndrome, an additional factor explaining the high prevalence of Alzheimer's disease in older people with the condition. The discovery paves the way for strategies to prevent and monitor the disease.

3 Oct 2025

Researchers uncover how chromosome crossovers protect fertility

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

24 Sep 2025

Lifespan study reveals age-specific biological changes in Down Syndrome

In a groundbreaking new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz discovered important differences in the physiological changes observed in over 300 individuals with Down syndrome across the lifespan.

24 Sep 2025

Adults with both Down Syndrome and congenital heart defects show remarkable resilience

Adults with both Down Syndrome and congenital heart defects, also known as congenital heart disease (CHD), are showing remarkable resilience despite facing significant medical challenges, according to a new MUSC study in Pediatric Cardiology.

19 Sep 2025

Montana advocates worry about federal impacts on support for students with disabilities

Tucker Jette lives for gaming, but like so many other recent high school graduates, he's had to come to terms with the reality that he can't make a living playing video games.

17 Sep 2025

Gene expression maps explain why diseases often occur together

This study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.

5 Sep 2025

Faster progression to severe diabetes observed in people with learning disabilities

People with learning disabilities progress faster to severe type 2 diabetes and are at greater risk of dying from their condition than people without these disabilities, suggests research published in the open access journal BMJ Open Diabetes Research & Control.

2 Sep 2025

Down Syndrome News and Research

Latest Down Syndrome News and Research

UCI MIND secures major funding for new Alzheimer's research facility

New discovery could reshape how scientists think about Alzheimer’s treatment

UC Davis researchers lead $5.5 million study on language development in children with Down syndrome

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

HMGN1 gene linked to heart problems in people with Down syndrome

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Study links high neuroinflammation in young people with Down Syndrome to Alzheimer's risk

Researchers uncover how chromosome crossovers protect fertility

Lifespan study reveals age-specific biological changes in Down Syndrome

Adults with both Down Syndrome and congenital heart defects show remarkable resilience

Montana advocates worry about federal impacts on support for students with disabilities

Gene expression maps explain why diseases often occur together

Faster progression to severe diabetes observed in people with learning disabilities

Researchers reveal how diseases interact at the genetic level

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

Alzheimer’s risk factors look different for men and women

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

Johns Hopkins uncovers protein's unexpected role in brain signaling

Proteome imbalance from aneuploidy linked to mitochondrial dysfunction

Study finds high levels of iron in the brains of people diagnosed with Down syndrome and Alzheimer's

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

Down Syndrome News and Research

Latest Down Syndrome News and Research

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

Newsletters you may be interested in