Endocrinology News and Research

Latest Endocrinology News and Research

New therapeutic approach for aggressive breast cancer

This type of TNBC tumor does not express any of the receptors involved in most breast cancers (estrogen, progesterone and HER2), so the most common treatments, such as the hormone therapy, are not viable in these patients.

25 May 2020

Inexpensive screening method for retinal changes in diabetics

Retinal damage due to diabetes is now considered the most common cause of blindness in working-age adults.

25 May 2020

Capillary leakage important in COVID-19 respiratory distress

Now, a new study published on the preprint server medRxiv reports the pivotal role played by protein leakage through lung capillaries and promotes the use of serum albumin as a biomarker of disease progression and severity.

24 May 2020

Smokers at increased risk of severe COVID-19 according to a large population study

A new UK study available on the preprint server medRxiv screened 2.4 million users of a symptom reporting application during the coronavirus disease (COVID-19) pandemic, revealing that smokers are at higher risk of increased symptom burden and more prone to hospitalization.

24 May 2020

Kidney transplants: Volume of services correlated with quality of treatment outcomes

In complex operations, is there a correlation between the volume of service provided per hospital and the quality of the treatment outcome? This question is addressed in eight commissions on minimum volumes that the Federal Joint Committee has issued to the Institute for Quality and Efficiency in Health Care.

22 May 2020

Blood test could help doctors identify patients at risk of developing type 2 diabetes

Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness during pregnancy.

22 May 2020

High pre-pregnancy glucose levels linked to adverse outcomes even in non-diabetic women

An elevated pre-pregnancy hemoglobin A1c--which measures average blood glucose concentration--is associated with a higher risk of adverse pregnancy outcomes even in women without known diabetes, according to a new study published this week in PLOS Medicine by Joel Ray of ICES and the University of Toronto, Canada, and colleagues.

22 May 2020

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

A large observational study suggests that treatment with the antimalarial drug chloroquine or its analog hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19.

22 May 2020

Scientists identify key cell signaling pathway that drives muscle loss

Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients.

22 May 2020

Study reveals mechanism involved in the development of diabetes, fatty liver

A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of Development of Advanced Therapy for Metabolic Disease, Kobe University Graduate School of Medicine) has clarified the mechanism underlying the development of diabetes and non-alcoholic steatohepatitis (NASH), a severe form of fatty liver.

22 May 2020

RYGB surgery patients can benefit from anti-obesity medications

Researchers have discovered that anti-obesity medications such as phentermine and topiramate, used individually or in combination, can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery, according to a retrospective study published online in Obesity, the flagship journal of The Obesity Society.

22 May 2020

UK has the largest gender health gap in G20, study reveals

According to WHO, men are living healthier and longer lives than ever before but are still more likely to be burdened by illness and are outlived by women in every country.

22 May 2020

New review analyzes evidence and strategies to manage the SARS-CoV-2 virus

How should orthopaedic surgeons respond to the COVID-19 pandemic? A review in The Journal of Bone & Joint Surgery analyzes evidence and strategies for managing the novel SARS-CoV-2 virus - including critical lessons from past pandemics.

22 May 2020

New tools for analyzing microbial communities

The June 2020 issue of Journal of Dental Research brings together a collection of the latest research on the oral microbiome.

22 May 2020

Researchers to use digital technologies to help tackle chronic disease

Sedentary behaviours, poor sleep and questionable food choices are major contributors of chronic disease, including diabetes, anxiety, heart disease and many cancers.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

New cooling insole helps reduce risk factor for diabetic foot ulcers

A new cooling insole developed by UT Southwestern scientists reduced the foot temperature of patients with diabetic neuropathy by several degrees, diminishing a significant risk factor for diabetic foot ulcers.

21 May 2020

RAAS inhibitors are safe to use in COVID-19 patients, study shows

The coronavirus disease (COVID-19) is a novel illness that has spread across the globe in just five months. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral infection binds to the angiotensin-converting enzyme 2 (ACE2) to enter and invade cells.

21 May 2020

Environmental chemicals linked to changes in the gut microbiome and health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

21 May 2020

Novel tool helps translate complex communication between microbes and the body

A new tool developed by scientists at the Quadram Institute and Earlham Institute is helping to translate the complex communication between the microbiome and the body.

21 May 2020