Endocrinology News and Research

Latest Endocrinology News and Research

Study finds gaps in guideline-based testosterone prescribing practices

Only a small number of men who were prescribed testosterone therapy received appropriate, guideline-concordant diagnostic testing, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill, by Sophia Sinha, M.D., clinical assistant professor at the University of Michigan in Ann Arbor, Mich.

14 Jun 2026

Testosterone benefits older men with T2D risk when combined with lifestyle changes

Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Eliminating dietary sugar may disrupt gut health and promote inflammation

Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Diabetes raises mortality risk after solid-organ transplantation

People with an organ transplant who develop or have existing diabetes are more likely to die than those without diabetes, according to a comprehensive analysis of solid-organ transplant recipients, which is being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Physical activity declines after starting GLP-1 obesity treatments

Adults with obesity losing weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

AI model could improve screening for primary aldosteronism

A study of a new AI model examining 30 years of routine electronic health records (EHR) data could improve screening for primary aldosteronism, a leading cause of high blood pressure that is often unrecognized but increases patients' risk of cardiovascular complications, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

New guideline recommends tailored care for precocious puberty

Some subgroups of children with precocious puberty-such as older girls with slowly progressing puberty-may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.

14 Jun 2026

Gut microbiome may determine bone loss severity in primary hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by excessive secretion of parathyroid hormone (PTH).

12 Jun 2026

Antibody profiles offer insights into long Covid cognitive symptoms

Persistent symptoms after COVID-19 infection continue to affect millions of people worldwide, even as the number of acute infections has declined.

12 Jun 2026

Advancing Cushing's syndrome diagnosis with salivary cortisone testing

Discover expert insights into Cushing's syndrome diagnosis using salivary cortisone testing and LC-MS/MS for improved accuracy.

From Waters Advanced Diagnostics 10 Jun 2026

Injectable semaglutide may improve fertility outcomes in PMOS

Researchers at the University of Colorado Anschutz have published a proof-of-concept study in Fertility and Sterility demonstrating that injectable semaglutide may offer meaningful reproductive benefits for women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS).

9 Jun 2026

Oral GLP-1 RA reduces blood glucose and bodyweight among people with type 2 diabetes

Oral GLP-1 medications have the potential to increase access to therapies that can help lower blood sugar and reduce bodyweight.

8 Jun 2026

Researchers challenge the traditional understanding of how histone deacetylase inhibitors function

Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function.

5 Jun 2026

Genetic testing identifies cause of pancreatic agenesis in infants

The DNA changes responsible for a rare genetic condition causing babies to be born without a pancreas can now be identified in almost all affected children through genetic testing.

1 Jun 2026

BMI may miss millions with obesity-related conditions

Could the way doctors traditionally measure obesity allow a subset of people with obesity-related health risks slip through the cracks?

1 Jun 2026

Mount Sinai opens integrated clinical center for womens health

The Mount Sinai Health System is opening the Carolyn Rowan Center for Women's Health and Wellness, a transformative new model for women's health that brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research innovation to deliver more personalized, comprehensive care for women across the entire lifespan.

27 May 2026

Retatrutide reshapes metabolism in obesity and type 2 diabetes, study finds

Retatrutide altered circulating metabolites and lipids linked to fatty acid oxidation and insulin resistance in people with obesity, with or without type 2 diabetes. These biomarker changes suggest improved metabolic health, but the post-hoc analysis remains hypothesis-generating and does not prove direct clinical benefit.

26 May 2026

Scientists discover how vitamin K pathway regulates bone remodeling

Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new bone, while osteoclasts (bone-resorbing cells) remove older mineralized tissue.

21 May 2026

Phase two clinical trial demonstrates dramatic mobility gains in children with severe fibrous dysplasia

Fibrous dysplasia is a rare skeletal disorder in which normal bone is gradually replaced by weak fibro-osseous tissue, leading to fractures, pain, deformities, and severe mobility impairment. In many patients, diseased bone tissue produces excessive amounts of fibroblast growth factor-23 (FGF23), a hormone that causes phosphate loss through the kidneys.

21 May 2026

Study reveals cellular mechanisms driving resistance to targeted cancer therapies

Despite impressive innovations in medicine, most advanced-stage cancers still carry a grim prognosis. Developing more effective treatments requires a deeper understanding of the cellular processes that drive the formation and growth of common cancers.

20 May 2026