Endocrinology News and Research

Latest Endocrinology News and Research

Study: 3D organization of chromosomes plays a role in cancer genomics

It is well understood that chromosomal translocation - a process whereby pieces of two chromosomes break off and exchange places - is a hallmark of many cancers including leukemia, thyroid cancer and lymphoma and play an important part in how healthy cells become cancerous. The role spatial proximity plays in why certain chromosomal translocations happen repeatedly, however, has been a long-standing area of debate among scientists.

17 Feb 2012

Longer looks: GOP contraceptive amendment could have wider effect; The love of caregiving

In their latest move in the battle over contraception coverage, top Republicans in Congress are going for broke: They're now pushing a bill that would allow employers and insurance companies to pick and choose which health benefits to provide based simply on executives' personal moral beliefs. ... Last week, Sen. Roy Blunt (R-Mo.) offered a "conscience amendment," to the law, pitching it as a way to allay religious employers' qualms about providing birth control to their employees.

17 Feb 2012

State roundup: Settlements for mental health facilities lawsuits; Minn., Oregon insurers face scrutiny

But the survey underway in Prince George's County is intended to address a complex problem. Officials expect the data to give them a detailed look at the state of health and health care in the county, where conditions such as diabetes and heart disease are much more common than in the rest of the region and most of the state.

17 Feb 2012

Collaborative Cross can help fast-track key discoveries about genetics and disease

A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross - a "library" of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.

17 Feb 2012

Scientists track initial steps of type 1 diabetes mellitus

Scientists have taken a remarkably detailed look at the initial steps that occur in the body when type 1 diabetes mellitus first develops in a child or young adult.

17 Feb 2012

Synthetic Oct4 protein more effective at turning genes into pluripotent stem cells

Scientists have found a way to generate and maintain stem cells much more efficiently by amplifying the effect of an essential protein.

17 Feb 2012

STRAW+10 report provides general road map to reproductive aging

Published simultaneously today in four top-tier journals, a new report provides a framework within which physicians and researchers can systematically and consistently identify the different reproductive stages women go though from adolescence to menopause and beyond. The report, named STRAW+10, will help clinicians predict when a woman will enter menopause and guide the selection of treatment options for menopausal symptoms and other related conditions.

17 Feb 2012

Amylin may lead to severe heart damage in obese and diabetic patients

Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, UC Davis researchers have found.

17 Feb 2012

Mechanical dose of load through muscle force may slow bone loss in SCI patients

Loss of bone density leads to brittle bones that fracture easily. It is a major complication of spinal cord injury (SCI), which affects about 250,000 Americans every year.

17 Feb 2012

Exposure to common flame retardant may affect fertility and long-term memory

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory when compared with the offspring of normal unexposed mice, a study by researchers at UC Davis has found.

16 Feb 2012

Biochemists determine first crystal structure of an immunoproteasome

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates uninfected cells by mistake.

16 Feb 2012

NCQA tool doesn't adequately evaluate quality of diabetes care at health centers

On the health front, the poor often have at least two things going against them: a lack of insurance and chronic illnesses, of which diabetes is among the most common.

16 Feb 2012

Despite fewer amputations, Medicare's bill for artificial feet rises 60%

The Associated Press examines the complicated issue of health costs by looking at foot amputations from diabetes.

16 Feb 2012

Diet exerts a strong influence on heart health

Food is your friend and your biggest foe. A healthy diet sustains us, but a poor diet can raise blood pressure, cholesterol, blood sugar levels and weight and put you at risk for heart disease.

16 Feb 2012

New parent-training program effective in reducing risk of obesity in preschool Latino children

A UCLA study has found that a new parent-training program is effective in reducing the risk of low-income, preschool-age Latino children being overweight.

16 Feb 2012

Drilling down into Obama's budget

The Wall Street Journal reports the plan would scale back money for public health and prevention programs; The Associated Press covers the debate about the proposed defense budget, which would scale back retirees' health coverage.

16 Feb 2012

RUMC conducts early phase trial of MSDC-0160 for dementia

Researchers at Rush University Medical Center are conducting an early phase clinical trial of a novel drug therapy for patients with dementia due to Alzheimer's disease. The drug is a new compound called MSDC-0160, which is an insulin sensitizer that modulates mitochondrial metabolism.

16 Feb 2012

Researchers identify potent regulator of sensitivity to insulin

Researchers at Washington University School of Medicine in St. Louis have identified a potent regulator of sensitivity to insulin, the hormone that controls blood sugar levels. The new findings may help scientists find better treatments for type 2 diabetes, obesity and other health problems caused by the body's inability to properly regulate blood sugar.

16 Feb 2012

Study: Diabetes may begin in the gut

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar - the hallmark of diabetes - may begin in the intestines.

15 Feb 2012

Large number of Australians with high blood pressure and heart disease risk

For the study researchers from Melbourne-based Baker IDI Heart and Diabetes Institute looked at medical records of 532,050 patients who visited GPs between 2005 and 2010 and found 36 per cent, had high blood pressure. At least 250,000 patients did not meet individual blood pressure targets, placing them at risk of future heart attacks or strokes.

15 Feb 2012