Endocrinology News and Research

Latest Endocrinology News and Research

Lung function, obstructive airway diseases linked with increased risk of heart failure

A large population-based study has found that lung function and obstructive airway diseases are strongly and independently associated with increased risk of heart failure. Importantly, say the investigators, this association was even evident in never-smokers and was still evident after adjustment for smoking status and number of years smoking. This, they add, indicates "that our results are not primarily confounded by smoking".

26 Feb 2012

Exelixis announces cabozantinib preclinical data on pancreatic cancer

Exelixis, Inc. today announced the company's lead compound, cabozantinib, is highlighted in a new peer-reviewed publication demonstrating that simultaneous inhibition of MET and VEGF signaling reduces tumor invasiveness and metastasis in preclinical models of pancreatic cancer.

26 Feb 2012

FDA panel votes in favor of earlier rejected anti-obesity drug Qnexa

Qnexa took a step closer to approval on Wednesday, when outside advisers to the U.S. Food and Drug Administration voted 20-to-2 in favor of approval. The panel also recommended the company conduct a study to scrutinize even more closely any risk of heart problems. That study may be required after the drug is approved. Should the FDA ask for further data on heart risks before any approval, it would delay Qnexa's launch further.

26 Feb 2012

Helmholtz Association grant for research on diseases caused by protein misfolding

Professor Erich Wanker of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and of the Excellence Cluster Neurocure is to receive EUR 675 000 in funding from the Helmholtz Association over the next two years. The grant shall be used to accelerate the search for active agents to treat diseases that are caused by protein misfolding. These include Alzheimer's and Parkinson's.

24 Feb 2012

Combined bioactive peptides successfully stimulate wound healing

Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds.

24 Feb 2012

Rhei granted marketing approval for MuGard in China

ACCESS PHARMACEUTICALS, INC., a biopharmaceutical company leveraging its proprietary drug-delivery platforms to develop treatments in areas of oncology, diabetes, and RNAi, announced that its MuGard partner in China, Rhei Pharmaceuticals HK Ltd., received regulatory and marketing approval for MuGard in China from the State Food and Drug Administration, or SFDA, to treat oral mucositis in cancer patients.

24 Feb 2012

Endo fourth quarter total revenues increase 57% to $803.4 million

Endo Pharmaceuticals today reported financial results for the fourth quarter of 2011.

24 Feb 2012

Ipsen, Active Biotech report data from tasquinimod Phase II study on CRPC

Active Biotech's and Ipsen's castrate resistant prostate cancer project, TASQ, will be presented at the 27th Annual EAU Congress held in Paris on 24-28 February 2012.

24 Feb 2012

Scientists identify specific mechanisms by which vitamin D inhibits inflammation

Researchers at National Jewish Health have discovered specific molecular and signaling events by which vitamin D inhibits inflammation. In their experiments, they showed that low levels of Vitamin D, comparable to levels found in millions of people, failed to inhibit the inflammatory cascade, while levels considered adequate did inhibit inflammatory signaling.

24 Feb 2012

'Good-times' pumps warn cells of approaching starvation

Sugar, cholesterol, phosphates, zinc - a healthy body is amazingly good at keeping such vital nutrients at appropriate levels within its cells. From an engineering point of view, one all-purpose model of pump on the surface of a cell should suffice to keep these levels constant: When the concentration of a nutrient, say, sugar, drops inside the cell, the pump mechanism could simply go into higher gear until the sugar levels are back to normal.

23 Feb 2012

DIRECT project to focus on stratification of patients with type 2 diabetes

Gathering experts from 21 European academic institutions and key players of the pharmaceutical industry, the DIRECT project (DIabetes REsearch for patient straTification) will focus on the stratification of patients with type 2 diabetes in order to develop personalized treatments, that would therefore be more efficient.

23 Feb 2012

Elevated levels of two TLRs can trigger heart disease and diabetes

UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases.

23 Feb 2012

Pediatricians should screen all children for vitamin D deficiency

As study after study shows the fundamental role vitamin D plays in disease and health, vitamin D deficiency — which often develops insidiously in childhood — should be on every parent's and pediatrician's radar, say physicians from the Johns Hopkins Children's Center.

23 Feb 2012

New Herman & Walter Samuelson Children's Hospital at Sinai to be dedicated on March 1

The new Herman & Walter Samuelson Children's Hospital at Sinai will be dedicated on Thursday, March 1. The 23,200-square-foot facility features 26 all-private rooms that support the very heart of the family-centered care philosophy. This method of care embraces the family as an integral part of the child's treatment and recovery. The family works alongside the clinical team to ensure the best outcomes for their sick child.

23 Feb 2012

State roundup: Calif. HMO report cards, Ore. family planning bills challenged, Texas managed care

Gov. Corbett's new budget proposal would cost the city $42 million in mostly mental health and addiction treatment funding, but city officials say the impact will be worsened by ensuing needs for emergency shelter, child welfare, and other services. … The city Health Department faces an additional $7 million in state cuts. That would reduce the number of beds in the city nursing home and cost hospice beds for AIDS victims, officials said.

23 Feb 2012

New kind of on-off switch for cortisol release in the brain discovered

After we sense a threat, our brain center responsible for responding goes into gear, setting off a chain of biochemical reactions leading to the release of cortisol from the adrenal glands.

23 Feb 2012

U.S. Surgeon General, SEMBC join to launch Fighting D in the D campaign

In her advocacy for effective disease prevention and health promotion programs, U.S. Surgeon General Regina M. Benjamin, M.D., joined the Southeast Michigan Beacon Community (SEMBC) today to launch the "Fighting D in the D" campaign during a kickoff event, attended by over 225 guests, at the Westin Book Cadillac in downtown Detroit.

23 Feb 2012

Novel test identifies toxic foods which, when avoided, will help lose weight

Why did Oprah say, "I hope he can show me how to stop craving potato chips" during her Tony Robbins' segment this week? Does she really think that her potato chip binging and craving causes all of her weight fluctuations? Researchers at the University of Miami Miller School of Medicine may have the answer hidden in a novel laboratory test called a Bloodprint® and published this month in the Journal of Obesity and Weight Loss Therapy.

23 Feb 2012

Silent & atypical heart attacks more dangerous & fatal in young women

It is known that chest pain or discomfort is the most common heart attack symptom. In addition, fatigue, nausea, shortness of breath and pain or numbness in the jaw, arms or back can also signal a blocked artery cutting off vital oxygen and nutrients from the heart.

22 Feb 2012

Southeast Minnesota Beacon Community to demonstrate HIE technology at HiMSS Conference

Medical records are an invaluable tool in treating patients. When a caregiver has ample information regarding a person's medical history, treatments are more effective and efficient. Unfortunately, few people have complete medical records -- due, in large part, to a lack of any universal repository tools for keeping those records.

22 Feb 2012

Endocrinology News and Research

Latest Endocrinology News and Research

Lung function, obstructive airway diseases linked with increased risk of heart failure

Exelixis announces cabozantinib preclinical data on pancreatic cancer

FDA panel votes in favor of earlier rejected anti-obesity drug Qnexa

Helmholtz Association grant for research on diseases caused by protein misfolding

Combined bioactive peptides successfully stimulate wound healing

Rhei granted marketing approval for MuGard in China

Endo fourth quarter total revenues increase 57% to $803.4 million

Ipsen, Active Biotech report data from tasquinimod Phase II study on CRPC

Scientists identify specific mechanisms by which vitamin D inhibits inflammation

'Good-times' pumps warn cells of approaching starvation

DIRECT project to focus on stratification of patients with type 2 diabetes

Elevated levels of two TLRs can trigger heart disease and diabetes

Pediatricians should screen all children for vitamin D deficiency

New Herman & Walter Samuelson Children's Hospital at Sinai to be dedicated on March 1

State roundup: Calif. HMO report cards, Ore. family planning bills challenged, Texas managed care

New kind of on-off switch for cortisol release in the brain discovered

U.S. Surgeon General, SEMBC join to launch Fighting D in the D campaign

Novel test identifies toxic foods which, when avoided, will help lose weight

Silent & atypical heart attacks more dangerous & fatal in young women

Southeast Minnesota Beacon Community to demonstrate HIE technology at HiMSS Conference

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Endocrinology News and Research

Latest Endocrinology News and Research

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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