Epilepsy News and Research

Latest Epilepsy News and Research

UCLA's non-invasive pre-surgical testing approach leads to seizure-free surgical outcome in TSC patients

When medication fails to control seizures in children with tuberous sclerosis complex (TSC), a rare genetic disorder that affects multiple organ systems and frequently causes epilepsy, surgery to remove part of the brain is often necessary. But pre-surgical testing, which involves the implanting of electrodes into a child's head, can lead to longer hospital stays and greater risks from surgery.

29 Jan 2010

Patients with epilepsy who take Ginkgo herbal medicines face increased risk of seizures

Restrictions should be placed on the use of Ginkgo biloba (G. biloba) - a top-selling herbal remedy - because of growing scientific evidence that Ginkgo may increase the risk of seizures in people with epilepsy and could reduce the effectiveness of anti-seizure drugs, a new report concludes.

28 Jan 2010

Sepracor's STEDESA NDA: FDA extends PDUFA action date

Sepracor Inc. today announced that it has received notification from the U.S. Food and Drug Administration (FDA) that the agency now anticipates completing its review of the STEDESA™ (eslicarbazepine acetate) New Drug Application (NDA) on April 30, 2010, which is a three-month extension to the original Prescription Drug User Fee Act (PDUFA) date of January 30, 2010.

28 Jan 2010

Large research gap exists in effectiveness, mechanism and safety of drugs in children

Only a few anti-spasticity medications used for children with cerebral palsy are backed by sufficient research to justify their use, according to a new review of scientific literature headed by a UT Southwestern Medical Center neurologist and conducted by a national panel of interdisciplinary experts nationwide.

27 Jan 2010

US PTO grants new allowances to intellectual property covering Neurologix' GAD based delivery systems

Neurologix, Inc., a biotechnology company engaged in the development of innovative therapies for the brain and central nervous system, announced that the U.S. Patent and Trademark Office (US PTO) has expanded the intellectual property protections enabled by a previously issued patent that is central to Neurologix’s Parkinson’s disease program. The new allowances to U.S. Patent Number 765,446, entitled “Glutamic acid decarboxylase (GAD) based delivery systems,” broaden the patent’s coverage beyond Parkinson’s disease to include the use of GAD65 in the treatment of other neurological and related disorders.

27 Jan 2010

Depomed plans additional Serada Phase 3 trial for treatment of menopausal hot flashes

Depomed, Inc. announced today it has received guidance from the FDA in formal meeting minutes from a meeting held in December regarding SeradaTM, the company’s extended release gabapentin product candidate for the treatment of menopausal hot flashes. Based on guidance reflected in the meeting minutes, Depomed plans to conduct a single additional pivotal Phase 3 trial evaluating Serada for the treatment of menopausal hot flashes.

20 Jan 2010

Dopamine replacement therapy causes brain dysfunction in patients with Parkinson disease, study says

People with Parkinson's Disease are more likely to display abnormal social behaviour and make poor decisions in ambiguous circumstances if they are pathological gamblers, according to research in the January issue of the European Journal of Neurology.

18 Jan 2010

New neuroprotective drug trial for people with traumatic brain injuries

A clinical trial of a new neuroprotective drug for people with traumatic brain injuries will be offered to patients seen in UC Davis Medical Center's level-1 trauma center, through an $8 million grant funded by the Congressionally Directed Medical Research Program of the U.S. Department of Defense.

18 Jan 2010

New discovery likely to have significant influence on cell replacement therapies

MIT neuroscientists have discovered that when it comes to new neurons in the adult brain, the squeakiest wheels get the grease.

18 Jan 2010

New research shows migraine and depression may share common genetic pathways

New research shows that migraine and depression may share a strong genetic component. The research is published in the January 13, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

18 Jan 2010

Zassi Medical Evolutions forms new company to develop electrical stimulation technology

Zassi Medical Evolutions, a privately held organization that innovates, designs and develops high technology medical devices and software announced today that it has successfully spun out and formed a new company with Tucson, Arizona based Research Corporation Technologies (RCT) to pursue the continued development of a novel electrical stimulation technology for the gastrointestinal continence control market.

13 Jan 2010

MedGenesis Therapeutix enters into license agreement with Amgen

MedGenesis Therapeutix Inc. ("MedGenesis"), a biopharmaceutical company developing and commercializing innovative treatments for patients with serious central nervous system (CNS) diseases, announced today that it has successfully entered into an agreement with Amgen Inc. ("Amgen"), granting MedGenesis an exclusive, worldwide license for glial cell line-derived neurotrophic factor (GDNF) protein in CNS and non-CNS indications, subject to the rights of a co-exclusive licensee for CNS indications in certain countries, as further described below.

12 Jan 2010

Web-based lesson voted "Educational Product of the Year"

"Principles of Rational Prescribing," a web-based lesson developed by faculty at Wake Forest University School of Medicine, was voted "Educational Product of the Year" recently among products developed by 40 academic geriatrics programs in the United States.

12 Jan 2010

Vertex Pharmaceuticals plans proof-of-concept clinical trials in RA and epilepsy

Vertex Pharmaceuticals Incorporated today provided an update on key 2010 business priorities in conjunction with the 28th Annual J.P. Morgan Healthcare Conference in San Francisco. The company also discussed recent progress in its lead development programs in hepatitis C virus (HCV) infection and cystic fibrosis (CF) and outlined proof-of-concept clinical trials planned in other serious diseases for 2010.

11 Jan 2010

Autism spectrum disorders result from miswiring of connections in developing brain

Studying a rare disorder known as tuberous sclerosis complex (TSC), researchers at Children's Hospital Boston add to a growing body of evidence suggesting that autism spectrum disorders, which affect 25 to 50 percent of TSC patients, result from a miswiring of connections in the developing brain, leading to improper information flow.

10 Jan 2010

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

Scientists have identified a gene underlying a disease that causes temporary paralysis of skeletal muscle. The finding, they say, illustrates how investigations of rare genetic diseases can drive insights into more common ones.

8 Jan 2010

Educational sessions and special workshops highlight advancements in molecular imaging

SNM's Conjoint Mid-Winter Meetings, Jan. 27-Feb. 2, 2010, in Albuquerque, N.M., will bring together four scientific meetings under one umbrella. The meeting, which provides attendees with the opportunity to earn up to 25 continuing education credits, will highlight the latest advancements in molecular imaging and nuclear medicine. The educational sessions will conclude with special workshops on nanomedicine and clinical trials.

7 Jan 2010

UV LED therapy can be used for treating focal epilepsy in humans

Researchers from the University of Minnesota Medical School discovered that light from an ultraviolet diode (UV LED) reduced "seizure-like" activity in a rat epilepsy model. During the study, UV light released gamma aminobutyric acid (GABA) from the "caged" compound carbonyl amino butanoic acid (BC204).

7 Jan 2010

New tools show potential for treating brain disorders

Neuroscientists at MIT have developed a powerful new class of tools to reversibly shut down brain activity using different colors of light.

7 Jan 2010

Talampanel slows progression of amyotrophic lateral sclerosis

A drug already used to treat symptoms of epilepsy has potential to slow the muscle weakening that comes with amyotrophic lateral sclerosis (ALS), scientists report after completing a Phase II clinical trial-an early, small-scale test to show if the drug works and continues to be safe.

5 Jan 2010

Epilepsy News and Research

Latest Epilepsy News and Research

UCLA's non-invasive pre-surgical testing approach leads to seizure-free surgical outcome in TSC patients

Patients with epilepsy who take Ginkgo herbal medicines face increased risk of seizures

Sepracor's STEDESA NDA: FDA extends PDUFA action date

Large research gap exists in effectiveness, mechanism and safety of drugs in children

US PTO grants new allowances to intellectual property covering Neurologix' GAD based delivery systems

Depomed plans additional Serada Phase 3 trial for treatment of menopausal hot flashes

Dopamine replacement therapy causes brain dysfunction in patients with Parkinson disease, study says

New neuroprotective drug trial for people with traumatic brain injuries

New discovery likely to have significant influence on cell replacement therapies

New research shows migraine and depression may share common genetic pathways

Zassi Medical Evolutions forms new company to develop electrical stimulation technology

MedGenesis Therapeutix enters into license agreement with Amgen

Web-based lesson voted "Educational Product of the Year"

Vertex Pharmaceuticals plans proof-of-concept clinical trials in RA and epilepsy

Autism spectrum disorders result from miswiring of connections in developing brain

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

Educational sessions and special workshops highlight advancements in molecular imaging

UV LED therapy can be used for treating focal epilepsy in humans

New tools show potential for treating brain disorders

Talampanel slows progression of amyotrophic lateral sclerosis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Epilepsy News and Research

Latest Epilepsy News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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