Estrogen News and Research

Latest Estrogen News and Research

Researchers identify potential therapeutic target for ER-negative breast cancer

Using a new in vivo screening system, Whitehead Institute researchers have identified a protein in the serine biosynthesis pathway that is essential in estrogen receptor (ER)-negative breast cancer—a notoriously difficult disease to treat associated with low five-year survival rates.

19 Jul 2011

Scientists identify new metabolic pathway for breast cancer

Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the rapidly emerging field of cancer metabolism, announced today a publication in the journal Nature that identifies dysregulated activity of the serine pathway as a novel metabolic target in certain breast cancers.

15 Jul 2011

CLEOPATRA Phase III study on HER2-positive mBC meets primary endpoint

Genentech, a member of the Roche Group, today announced that CLEOPATRA, a pivotal Phase III study, met its primary endpoint.

15 Jul 2011

Treatment with estrogen dramatically lowers rates of stomach cancer in male mice

Several types of cancer, including stomach, liver and colon, are far more common in men than in women. Some scientists have theorized that differences in lifestyle, such as diet and smoking, may account for the discrepancy, but growing evidence suggests that the differences are rooted in basic biological differences between men and women.

14 Jul 2011

Progesterone could fight against neuroblastoma

High doses of the hormone progesterone can kill neuroblastoma cells while leaving healthy cells unscathed, scientists at Emory University School of Medicine have found in laboratory research.

14 Jul 2011

Penis size linked to finger length: Study

A new South Korean study shows that the ratio of the length of a man's index finger to that of his ring finger is linked with penis size. The lower the ratio the longer the penis, say researchers. The study was published in the Asian Journal of Andrology.

7 Jul 2011

Women more likely to survive after major gastrointestinal surgeries than men

In the first study to consider the impact of gender on patient outcomes in major gastrointestinal surgeries, researchers at UC San Diego Health System have found that women are more likely to survive after the procedure than men.

1 Jul 2011

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified has important implications for treatment and outcomes for women diagnosed with breast cancer. Its findings are published online in the June 28 Journal of Clinical Oncology.

28 Jun 2011

Researchers demonstrate how Runx3 protein could suppress breast cancer tumor growth

Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, accomplishes this feat.

27 Jun 2011

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

NJIT Research Professor Mike Jaffe's recent book chapter about sugar-based chemicals is topping the American Chemical Society (ACS) book series' must-read list.

22 Jun 2011

GTx commences Capesaris Phase IIb trial in advanced prostate cancer

GTx, Inc., announced today that it initiated a Phase IIb clinical trial evaluating Capesaris, a selective estrogen receptor alpha agonist, compared to Lupron Depot for first line treatment of advanced prostate cancer.

20 Jun 2011

Scientists create first roadmap to understand estrogen signaling in breast cancer cells

The first roadmap to mathematical modeling of a powerful basic "decision circuit" in breast cancer has been developed and published in Nature Reviews Cancer.

18 Jun 2011

Food-based soy products safe for breast cancer survivors, expert says

There has been widespread concern about whether it is safe for women with breast cancer to eat soy. An excellent source of fiber, vitamin B6 and protein, soy is usually associated with a health-conscious diet, but research concerning its safety has been mixed.

17 Jun 2011

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Synta Pharmaceuticals Corp. today presented results at the Annual Meeting of the American Society for Clinical Oncology (ASCO) from a Phase 2 single agent clinical trial of ganetespib in gastrointestinal stromal tumors (GIST) and a Phase 1 trial of ganetespib in solid tumors evaluating a twice-weekly administration schedule.

7 Jun 2011

Flaxseed of no use in menopausal hot flashes: Study

Flaxseed has been the latest agent that has been tried in treating menopausal hot flashes and it is seen that it does not reduce the incidence of the unpleasant symptoms.

7 Jun 2011

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Estrogen therapy improves low bone density due to anorexia nervosa in teenage girls with the disease when given as a patch or as a low oral dose that is physiological.

6 Jun 2011

$Skin wrinkles may allow identification of fracture risk in early menopausal women$

Estrogen News and Research

Latest Estrogen News and Research

Researchers identify potential therapeutic target for ER-negative breast cancer

Scientists identify new metabolic pathway for breast cancer

CLEOPATRA Phase III study on HER2-positive mBC meets primary endpoint

Treatment with estrogen dramatically lowers rates of stomach cancer in male mice

Progesterone could fight against neuroblastoma

Penis size linked to finger length: Study

Women more likely to survive after major gastrointestinal surgeries than men

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

Researchers demonstrate how Runx3 protein could suppress breast cancer tumor growth

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

GTx commences Capesaris Phase IIb trial in advanced prostate cancer

Scientists create first roadmap to understand estrogen signaling in breast cancer cells

Food-based soy products safe for breast cancer survivors, expert says

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Flaxseed of no use in menopausal hot flashes: Study

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Skin wrinkles may allow identification of fracture risk in early menopausal women

NCIC CTG's exemestane clinical trial data on breast cancer presented at ASCO 2011

New study shows Bisphenol A exposure through diet has been underestimated

Study suggests strong link between dying from breast cancer and being obese

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Estrogen News and Research

Latest Estrogen News and Research

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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