Estrogen News and Research

Latest Estrogen News and Research

Stress on a daily basis protects against breast cancer

According to recently published research, women with high levels of stress in their everyday lives, are at less risk than others of developing primary breast cancer.

10 Sep 2005

Putting the risk of breast cancer and postmenopausal Hormone Therapy (HT) into perspective

Two similar comprehensive literature reviews and an editorial about the varying risk with different postmenopausal hormone therapy regimens have been published this month in Human Reproduction Update.

7 Sep 2005

Methoxychlor (MXC) may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women

The researchers found that MXC, which was manufactured as a safer replacement for the now-banned DDT, alters the estrogen-regulated gene Hoxa10 in the reproductive tract and reduces the ability of the uterus to support embryo implantation. The researchers used mice and then human cell lines to confirm their findings.

7 Sep 2005

Letrozole following tamoxifen may benefit women with breast cancer

Switching to the drug letrozole following 5 years of treatment with tamoxifen reduces the risk of hormone-dependent breast cancer recurrence, but not overall survival, among postmenopausal women, according to a new study in the September 7 issue of the Journal of the National Cancer Institute.

7 Sep 2005

Fine-tuning fertility testing with take-home technology

A take-home fertility-testing kit under development in a Massey University laboratory will give women and couples further control over pregnancy planning.

6 Sep 2005

For post-menopausal women light to moderate exercise is best

A British expert says that although exercise is important for reducing the risk of osteoporosis and heart disease in post-menopausal women, too much exercise in pre-menopausal women may actually increase the risks.

5 Sep 2005

Recent evidence suggests caution in prescribing hormone therapy for breast cancer

One of the most effective new treatments for breast cancer is a hormone therapy. Aromatase inhibitors work by powerfully blocking the conversion of androgen precursors into estrogens, which lowers estradiol levels in the bloodstream and estrogen levels in peripheral tissues.

4 Sep 2005

Long-term hormone therapy used earlier in menopause is associated with fewer wrinkles

Long-term hormone therapy used earlier in menopause is associated with fewer wrinkles and less skin rigidity in postmenopausal women, Yale School of Medicine researchers report in the August issue of Fertility and Sterility.

28 Aug 2005

UCI study helps identify one reason why women have lower stroke risk than men

Estrogen's role as an inhibitor of toxic-free radicals in cerebral blood vessels may be a key reason why premenopausal women have a lower stroke risk than men.

26 Aug 2005

Analytical tool to help detect cancer

Scientists have long used ultra-fine glass tubes known as capillaries to analyze the chemical makeup of substances. Called capillary electrophoresis, or CE, the method applies high voltage to the capillaries, and by measuring the rate that the various materials move through the capillaries, researchers are able to identify individual compounds.

16 Aug 2005

Effects of estrogen on heart disease prevention

Researchers at Yale School of Medicine and seven other national institutions are recruiting patients to participate in the Kronos Early Estrogen Prevention Study (KEEPS) to look at the effects of estrogen on heart disease prevention.

15 Aug 2005

MiRNA is opening up a whole new way of understanding carcinogenesis

Scientists mining vast, largely unexplored regions of the human genome have identified a small handful of mini-molecules that play a major role in the development of cancer and perhaps many other diseases.

15 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Important breast cancer discovery

Scientists at the McGill University Health Centre (MUHC) have made an important discovery that will advance our understanding of how the female hormone estrogen causes growth of breast cancer cells. The research, in collaboration with scientists at the Institut de Recherches Cliniques de Montreal (IRCM) identifies 153 genes that respond to estrogen and one in particular that can be used to halt the growth of breast cancer cells.

10 Aug 2005

Study results reaffirm cyclin D1 as a candidate target for molecular therapeutic control of breast tumor development

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases arise from these genetic miscues, about half of which are linked to the abnormal functioning of BRCA1.

9 Aug 2005

New study says HRT risks far lower

Women battling to deal with the miserable effects of the menopause, will be even more confused by the release of a new Australian study, which says that a woman's risk of developing breast cancer after taking hormone replacement therapy (HRT) might be lower than previously thought.

7 Aug 2005

Hormone replacement therapy and breast cancer

A woman's risk of developing breast cancer while taking hormone replacement therapy may be lower than we think, suggest researchers in this week’s British Medical journal (BMJ).

4 Aug 2005

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1.

2 Aug 2005

Bone marrow may be source of new egg-cell generation

Last year a group of Massachusetts General Hospital (MGH) researchers announced surprising findings that female mice - contrary to longstanding theories of mammalian reproductive physiology - retained the ability to make new egg cells or oocytes into adulthood.

27 Jul 2005

Plaques in the brain more likely to be expressed as dementia in women than in men

Researchers from the Rush Alzheimer's Disease Center found that plaques and tangles in the brain, the changes seen in people with Alzheimer's disease (AD), are more likely to be expressed as dementia in women than in men.

25 Jul 2005