Estrogen News and Research

Latest Estrogen News and Research

IMS develops review on weight gain at the menopause

To mark World Menopause Day (18th October) the International Menopause Society has developed a state-of-the-science review on weight gain at the menopause. This report is published in the peer-reviewed journal, Climacteric.

16 Oct 2012

Neurotensin as an indicator for poor health outcomes in women

The satiety hormone neurotensin may provide a novel biomarker for assessing risk for diabetes, cardiovascular disease, and breast cancer among women, report researchers.

12 Oct 2012

Sun protection: an interview with Jane Hanrahan

UV radiation is a form of energy being transmitted. Sunlight is main source of UV radiation, although manmade sources also exist, such as the lamps used in sunbeds. At the earth’s surface sunlight consists of approximately 2 percent UV light, 47 percent visible light and 51 percent IR light.

11 Oct 2012

IspH protein accepts two completely different classes of molecules as partners

The iron-sulfur protein IspH plays a central role in the terpene metabolism of several pathogens. The mechanism of the reaction provides an approach for developing new antibiotics, particularly against malaria and tuberculosis. While researching this enzyme, biochemists at the Technische Universitat Munchen discovered a previously unknown reaction: IspH accepts two completely different classes of molecules as partners.

10 Oct 2012

Clinical trial to investigate safety and effectiveness of Elagolix against endometriosis

According to the Centers for Disease Control (CDC), endometriosis, a gynecological disorder in which cells from the uterus lining grow in other areas of the body, is the number one reason for a hysterectomy in women ages 18-35. Current treatment options for endometriosis are severely limited by side effects of existing medications and surgical options have more risks. A nationwide clinical trial is testing an investigational drug as a potential new option for patients with moderate to severe pain from this disease.

9 Oct 2012

Fertility treatment may increase MS disease activity

Findings published in Annals of Neurology suggest that assisted reproduction technology treatment increases multiple sclerosis disease activity.

8 Oct 2012

Hormone therapy offsets adverse metabolic effects of menopause

Long-term hormone therapy helps prevent the adverse metabolic effects that occur following menopause, research shows.

4 Oct 2012

BPA exposure can impact thyroid hormones in pregnant women and newborns

Bisphenol A (BPA), an estrogen-like compound that has drawn increased scrutiny in recent years, has been linked to changes in thyroid hormone levels in pregnant women and newborn boys, according to a new study by researchers at the University of California, Berkeley.

4 Oct 2012

Estrogen/progesterone treatment started soon after menopause appears safe and effective

Estrogen/progesterone treatment started soon after menopause appears safe and relieves many of the symptoms menopausal women face as well as improving mood and markers of cardiovascular risk, according to a multicenter randomized study presented at the North American Menopause Society (NAMS) Annual Meeting in Orlando, Florida.

4 Oct 2012

Positive results from Noven’s LDMP Phase 3 clinical studies on menopausal VMS

Noven Pharmaceuticals, Inc., a wholly-owned subsidiary of Hisamitsu Pharmaceutical Co., Inc., today announced positive results from two multicenter, double-blind, randomized, placebo-controlled Phase 3 clinical studies evaluating low-dose mesylate salt of paroxetine (LDMP; 7.5 mg/day) for the treatment of moderate to severe vasomotor symptoms (VMS) associated with menopause.

3 Oct 2012

ProStrakan acquires US commercial rights to Fareston for treatment of metastatic breast cancer

ProStrakan Group plc announces today that it has acquired exclusive US commercial rights to Fareston (toremifene citrate) for the treatment of metastatic breast cancer in postmenopausal women.

1 Oct 2012

HR status defines two different subsets of HER2 positive cancers

Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows that women whose HER2 positive cancer was also hormone (estrogen and progesterone) receptor (HR) negative had an increased risk of early death, and that their cancer was less likely to recur in bone than those whose cancer retained hormone sensitivity.

1 Oct 2012

Regular mammography screening can help narrow racial gaps in breast cancer outcomes

Regular mammography screening can help narrow the breast cancer gap between black and white women, according to a retrospective study published in Breast Cancer Research and Treatment in August.

26 Sep 2012

Researchers discover path to identify why genetic variants increase breast cancer risk

Cancer researchers studying 44 known genetic variants associated with breast cancer have found the way to identify why they increase cancer risk, opening the door to future therapeutic applications based on personalized medicine.

25 Sep 2012

Aromatase inhibitors impact sex life of postmenopausal women with breast cancer

Women treated for breast cancer after menopause with aromatase inhibitors have very high levels of sexual difficulties, including low interest, insufficient lubrication, and pain with intercourse. It is an important and underestimated problem, say the authors of a study published online in Menopause, the journal of the North American Menopause Society.

25 Sep 2012

Marijuana and testicular cancer: an interview with Victoria Cortessis

This is a set of malignancies that arise in germ cells of the testicles, the specialized cells that produce sperm. Taken together, testicular cancers are the most common form of malignancy that occurs in young men (approximately 15 to 35 years of age).

24 Sep 2012

Molecular similarity between one sub-type of breast cancer and ovarian cancer

A team of scientists with The Cancer Genome Atlas program reports their genetic characterization of 800 breast tumors, including finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer.

24 Sep 2012

Most basal-like breast and ovarian tumors have similar genetic origins

The most comprehensive analysis yet of breast cancer shows that one of the most deadly subtypes is genetically more similar to ovarian tumors than to other breast cancers.

24 Sep 2012

Women with early menopause more likely to develop coronary heart disease and stroke

Women who go into early menopause are twice as likely to suffer from coronary heart disease and stroke, new Johns Hopkins-led research suggests. The association holds true in patients from a variety of different ethnic backgrounds, the study found, and is independent of traditional cardiovascular disease risk factors, the scientists say.

19 Sep 2012

Study could reveal whether breast cancer patients with BRCA mutations are responsive to Veliparib

Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an investigational drug believed to hamper cancer cells.

15 Sep 2012