Fatty Liver News and Research

Latest Fatty Liver News and Research

NIH supports research to understand the genome-metal interactions in nonalcoholic fatty liver disease

Wanqing Liu, Ph.D., professor of pharmaceutical sciences in the Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences and of pharmacology in Wayne State's School of Medicine, received a $3 million, five-year award from the National Institute of Environmental Health Sciences of the National Institutes of Health.

21 Aug 2023

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population.

18 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States.

9 Aug 2023

Spatially-resolved macrophage phenotyping in liver disease-related research

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.

8 Aug 2023

Impact of age-related alterations in lipid metabolism on general health

Scientists provide a detailed overview on age-related alterations in lipid metabolism and its association with age-related chronic diseases.

8 Aug 2023

How do dietary patterns influence inflammatory bowel disease?

Researchers used bibliometrics to analyze studies describing the effects of dietary patterns on inflammatory bowel disease (IBD).

7 Aug 2023

Researchers discover how aging can lead to chronic metabolic disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

3 Aug 2023

AGA announces support for the reintroduced Treat and Reduce Obesity Act

The American Gastroenterological Association (AGA) today announced support for the reintroduced Treat and Reduce Obesity Act (TROA), which would expand Medicare coverage to include screening and treatment of obesity from a diverse range of health care providers who specialize in obesity care.

3 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Researchers evaluated the physiological roles of an antimicrobial peptide.

3 Aug 2023

Review studies relationships between vitamin E intake or circulating α-tocopherol and various health outcomes

In a recent study, researchers examined the relationships between vitamin E or circulating α-tocopherol intake and health outcomes using a meta-analyses.

2 Aug 2023

Fructose identified as central conduit to obesity

Researchers at the University of Colorado Anschutz Medical Campus have officially identified a central conduit to obesity: fructose.

1 Aug 2023

The microbiota connection, gut health linked to metabolic syndrome prevalence

The relationship between gut microbiota and metabolic disorders focused on BA metabolism and immunity.

1 Aug 2023

New method improves prediction of liver disease progression

A research team from the Department of Medicine III at MedUni Vienna and University Hospital Vienna has conducted a large-scale study showing the important value of repeated liver assessments by a novel method that can significantly improve risk assessment in patients with chronic liver disease.

17 Jul 2023

Growth factor study reveals potential breakthrough in obesity management

Study discusses the effects of a growth factor that showed promising results in mice in an obesity trial.

4 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023