Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Regulation of fat production is abnormal in obesity, shows study

Gut hormones play an important role in regulating fat production in the body. One key hormone, released a few hours after eating, turns off fat production by regulating gene expression in the liver, but this regulation is abnormal in obesity, researchers at the University of Illinois Urbana-Champaign found in a new study.

25 Nov 2020

Bariatric surgery linked to lower risk of hospital and intensive care unit admission

A Cleveland Clinic study shows that among patients who have obesity and who tested positive for COVID-19, a past history of bariatric surgery was significantly associated with a lower risk of hospital and intensive care unit admission.

24 Nov 2020

Antimicrobial found in soaps worsens fatty liver disease in mice

University of California San Diego School of Medicine researchers found evidence that triclosan -- an antimicrobial found in many soaps and other household items -- worsens fatty liver disease in mice fed a high-fat diet.

23 Nov 2020

Scientists find significant differences in liver-related mortality rates in the U.S

When they set out to study local levels of death from liver diseases in the U.S., University of Miami Miller School of Medicine and Emory researchers found significant differences in death rates even within the same state, according to a recently published study in Gastroenterology.

19 Nov 2020

UC researcher receives $443,000 NIH grant to study antiviral drugs

University of Cincinnati pharmaceutical sciences researcher Bingfang Yan, DVM, has received a $443,000 grant from the National Institutes of Health to study how common medicines against viral infections are genetically impacted for therapeutic effectiveness and safety through metabolic conversions in the body.

18 Nov 2020

Study identifies new factor that offers potential strategy for treating obesity

Obesity is a serious global health problem and a risk factor for diseases such as type II diabetes, heart disease and fatty liver disease.

17 Nov 2020

Short bursts of intense exercise could help people get fit in time for summer

Short bursts of intense exercise – known as HIIT – could help you get back into shape by summer and stay that way, a UNSW Sydney exercise physiology researcher says.

17 Nov 2020

A substantial minority of middle-aged adults have liver fibrosis

A substantial minority of participants from the Framingham Heart Study, (nearly nine percent), had potentially clinically significant liver fibrosis (scarring). This the first study of this size and scale done in the United States.

9 Nov 2020

RA guidelines stress on minimizing steroids and maximizing methotrexate, biologics

The American College of Rheumatology (ACR) will preview its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the ACR's annual meeting. The comprehensive, clinical recommendations for pharmacologic treatment of RA includes important updates to the previous guideline released in 2015.

9 Nov 2020

Dietary supplement helps prevent fatty liver disease in rats

A recent study by researchers at the University of Jyväskylä was successful in partially preventing fatty liver disease in rats.

4 Nov 2020

Scientists use new approach to analyze millions of chemical-gene interactions

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan.

29 Oct 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

CN Bio announces launch of drug metabolism and safety toxicity testing services

CN Bio, a leading 3D cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced the commercial launch of its Drug Metabolism and Safety Toxicity Testing Services.

28 Oct 2020

Researchers discover novel protocol to detect lipid production in microalgae

Dietary supplementation of fatty acids produced from microalgae have wide-reaching health benefits for humans, including the ability to reduce obesity, diabetes and fatty liver disease, preventing hair loss, and assisting wounds to heal.

16 Oct 2020

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Inlighta Biosciences, LLC, a start-up company led by Jenny Yang, Regents' Professor of Chemistry at Georgia State University, has been awarded a National Institute of Health grant to accelerate development of a magnetic resonance imaging contrast agent to detect liver fibrosis, formation of scar tissue in the liver caused by alcoholic and non-alcoholic fatty liver disease.

15 Oct 2020

Even mild fatty liver disease associated with higher risk of all-cause mortality

Non-alcoholic fatty liver disease, NAFLD, affects nearly one in four adults in Europe and the U.S. Earlier research has demonstrated an increased risk of death in patients with NAFLD and advanced fibrosis or cirrhosis.

12 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease.

6 Oct 2020

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

Fatty Liver

Overview

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Latest Fatty Liver News and Research

Regulation of fat production is abnormal in obesity, shows study

Bariatric surgery linked to lower risk of hospital and intensive care unit admission

Antimicrobial found in soaps worsens fatty liver disease in mice

Scientists find significant differences in liver-related mortality rates in the U.S

UC researcher receives $443,000 NIH grant to study antiviral drugs

Study identifies new factor that offers potential strategy for treating obesity

Short bursts of intense exercise could help people get fit in time for summer

A substantial minority of middle-aged adults have liver fibrosis

RA guidelines stress on minimizing steroids and maximizing methotrexate, biologics

Dietary supplement helps prevent fatty liver disease in rats

Scientists use new approach to analyze millions of chemical-gene interactions

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

CN Bio announces launch of drug metabolism and safety toxicity testing services

Researchers discover novel protocol to detect lipid production in microalgae

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Even mild fatty liver disease associated with higher risk of all-cause mortality

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

NIH awards grants for using bioengineered models to improve clinical trial design

Could beta-blockers be a potential treatment for COVID-19?

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

The Prospects of Semaglutide for Treatment of Type 2 Diabetes Patients

Fatty Liver

Overview

Latest Fatty Liver News and Research

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