Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Acute Fatty Liver of Pregnancy Treatment

Fatty Liver Diagnosis

Uncovering the hidden metabolic effects of soybean oil

Soybean oil, the most widely consumed cooking oil in the United States and a staple of processed foods, contributes to obesity, at least in mice, through a mechanism scientists are now beginning to understand.

27 Nov 2025

Combined healthy eating and exercise linked to greater reductions in visceral fat

Improving diet and increasing physical activity levels together may be more effective at preventing weight gain – particularly harmful fat inside the abdomen – than just changing one of these behaviours, new research from the University of Cambridge suggests.

21 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

BMI is failing to detect dangerous obesity as people age

A landmark study finds waist-to-height ratio more effective than BMI in identifying obesity risk, as central fat levels rise across the UK population.

19 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to advance precision diagnostics and significantly improve chronic disease outcomes for at-risk patients, today announced a collaboration with a leading global pharmaceutical company recognized for its expertise in precision medicine and biomarker-guided drug development.

From Mursla Bio 13 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

How artificial light interferes with liver health

People who work against their internal clock over a long period of time increase the risk of fatty liver. The correlations are complex, but one research team in Bochum is trying to get to the bottom of the issue.

4 Nov 2025

Liver alterations associated with MASLD can directly affect the brain and behavior

A multidisciplinary research team has discovered that liver alterations associated with metabolic dysfunction-associated fatty liver disease (MASLD) can directly cause cognitive and neurological impairments, and that these effects can be reversed by a therapy exclusively targeting the liver.

30 Oct 2025

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

Athletes may gain health and performance advantages from time-restricted eating

According to a study by researchers at the Universitat Oberta de Catalunya (UOC), time-restricted feeding can have a positive impact on athletes in terms of both their health and performance.

8 Oct 2025

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

A major new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD).

6 Oct 2025

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third of the adult population. This disorder is characterized by the accumulation of fat in liver cells, which has severe liver consequences and is also associated with a high mortality rate from cardiovascular disease.

6 Oct 2025

New quintuple agonist shows promise for treating obesity and type 2 diabetes

Much excitement has built in recent years on the new class of incretin drugs that include glucagon-like-peptide-1 inhibitor (single agonists such as semaglutide) and also dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonists (dual agonists such tirzepatide).

21 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Fatty Liver

Overview

Fatty Liver Pathology

Acute Fatty Liver of Pregnancy Treatment

Fatty Liver Diagnosis

Latest Fatty Liver News and Research

Uncovering the hidden metabolic effects of soybean oil

Combined healthy eating and exercise linked to greater reductions in visceral fat

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

BMI is failing to detect dangerous obesity as people age

Understanding leptin's dual function in MAFLD pathogenesis

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

How artificial light interferes with liver health

Liver alterations associated with MASLD can directly affect the brain and behavior

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

Scientists question the safety and efficacy of the diet for metabolic health

Study links gut dysbiosis with severe steatosis in MASLD

Athletes may gain health and performance advantages from time-restricted eating

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

New quintuple agonist shows promise for treating obesity and type 2 diabetes

PANoptosis emerges as a promising strategy against liver cancer

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Fatty Liver

Overview

Latest Fatty Liver News and Research

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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