Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

New study helps better understand the pathology of fatty liver disease MASH

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

24 Jul 2024

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

An international study has discovered that people living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time.

17 Jul 2024

Ultrasound techniques for the surveillance, diagnosis, and treatment of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and one of the leading causes of cancer-related deaths worldwide. Early detection and accurate diagnosis are crucial for effective management and improved survival rates.

16 Jul 2024

What is the association of Mediterranean diet–based interventions with cardiometabolic biomarkers in children and adolescents?

Researchers reviewed and meta-analyzed the randomized clinical trials (RCTs) assessing the effects of Mediterranean diet -based interventions on cardiometabolic biomarkers in children and adolescents.

16 Jul 2024

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors.

15 Jul 2024

Do probiotics really benefit healthy people?

Recent research in Advances In Nutrition reviews the benefits of probiotics for healthy individuals, highlighting evidence gaps and the need for further study to support preventive recommendations.

14 Jul 2024

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

A recent meta-analysis in Nutrients examined recent studies on the cornelian cherry, Cornus mas L., for evidence of its cardiometabolic benefit.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Aging aggravates liver fibrosis in Down Syndrome, new study finds

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 12, entitled, "Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome."

10 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

The Korea Research Institute of Standards and Science (KRISS) has developed the world's first reference material to improve the accuracy of body fat measurements conducted through MRI and CT scans.

1 Jul 2024

New study reveals ketogenic diet's role in combating obesity

Researchers showed that ketogenic diet (KD)-induced bile acids (BAs) are protective against obesity.

1 Jul 2024

Using liver biopsies to identify predictors of pancreatic cancer metastasis

Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual's liver or elsewhere, such as the lung.

28 Jun 2024

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

26 Jun 2024

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

Metabolic-associated fatty liver disease (MAFLD) may increase the risk of cardiovascular events. In this study, we assessed the predictive value of pentraxin 3 (PTX3) for severe fibrosis and carotid intima-media thickness (CIMT) in patients with MAFLD.

25 Jun 2024

Early management of gestational diabetes can prevent maternal and child health complications

Speaking at the American Diabetes Association 84th Scientific Sessions, authors of a new Lancet Series challenge current approaches to managing gestational diabetes (a type of diabetes that can be diagnosed during pregnancy) and call for initiating treatment much earlier to prevent complications during pregnancy and beyond.

19 Jun 2024

Empowering communities: Penn Medicine's annual mammogram event and health fair

Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.

13 Jun 2024

Fatty Liver

Overview

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Latest Fatty Liver News and Research

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

New study helps better understand the pathology of fatty liver disease MASH

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

Ultrasound techniques for the surveillance, diagnosis, and treatment of hepatocellular carcinoma

What is the association of Mediterranean diet–based interventions with cardiometabolic biomarkers in children and adolescents?

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Do probiotics really benefit healthy people?

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

Existing drug shows promise for treating common liver disease

Aging aggravates liver fibrosis in Down Syndrome, new study finds

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

No organ is an island: Genetic study shows unique but interconnected aging markers

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

New study reveals ketogenic diet's role in combating obesity

Using liver biopsies to identify predictors of pancreatic cancer metastasis

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

Early management of gestational diabetes can prevent maternal and child health complications

Empowering communities: Penn Medicine's annual mammogram event and health fair

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

Fatty Liver

Overview

Latest Fatty Liver News and Research

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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