Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Acute Fatty Liver of Pregnancy Treatment

Fatty Liver Pathology

Fatty Liver Diagnosis

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

Athletes may gain health and performance advantages from time-restricted eating

According to a study by researchers at the Universitat Oberta de Catalunya (UOC), time-restricted feeding can have a positive impact on athletes in terms of both their health and performance.

8 Oct 2025

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

A major new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD).

6 Oct 2025

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third of the adult population. This disorder is characterized by the accumulation of fat in liver cells, which has severe liver consequences and is also associated with a high mortality rate from cardiovascular disease.

6 Oct 2025

New quintuple agonist shows promise for treating obesity and type 2 diabetes

Much excitement has built in recent years on the new class of incretin drugs that include glucagon-like-peptide-1 inhibitor (single agonists such as semaglutide) and also dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonists (dual agonists such tirzepatide).

21 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

Researchers used drug-target Mendelian randomization to test whether genetically proxied activation of GLP1R and GIPR influences alcohol-related behaviors. They found that GIPR, especially when combined with GLP1R, was linked to lower binge and heavy drinking, healthier food preferences, improved liver markers, and reduced coronary artery disease risk.

15 Sep 2025

Neuritin 1 unlocks new pathway to treat obesity without reducing food intake

Is it possible to treat obesity without reducing food intake? A new study co-led by Dr. Antonio Zorzano and Dr. Manuela Sánchez-Feutrie at the Institute for Research in Biomedicine (IRB Barcelona) suggests that this might be a possibility, at least in animal models.

4 Sep 2025

Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer

Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease.

3 Sep 2025

Visualizing lipid transport inside living cells with fluorescence microscopy

Lipid molecules, or fats, are crucial to all forms of life. Cells need lipids to build membranes, separate and organize biochemical reactions, store energy, and transmit information.

29 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

Promising treatment slows liver cancer by inhibiting fat enzyme

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease.

31 Jul 2025

Promising new treatment helps the immune system attack and destroy liver tumors

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease.

30 Jul 2025

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body.

30 Jul 2025

Rising liver cancer rates highlight need for urgent action worldwide

The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease – previously called non-alcoholic fatty liver disease), suggests an analysis as part of The Lancet Commission on liver cancer.

29 Jul 2025

Substance use disorders increase risk of unplanned hospital readmissions

People with any type of substance use disorder (SUD) stand a 24% higher risk of having an unplanned hospital readmission within 30 days of a previous discharge compared with those without the disorder, new UCLA-led research finds.

23 Jul 2025

Fatty Liver

Overview

Acute Fatty Liver of Pregnancy Treatment

Fatty Liver Pathology

Fatty Liver Diagnosis

Latest Fatty Liver News and Research

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

Scientists question the safety and efficacy of the diet for metabolic health

Study links gut dysbiosis with severe steatosis in MASLD

Athletes may gain health and performance advantages from time-restricted eating

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

New quintuple agonist shows promise for treating obesity and type 2 diabetes

PANoptosis emerges as a promising strategy against liver cancer

Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

Neuritin 1 unlocks new pathway to treat obesity without reducing food intake

Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer

Visualizing lipid transport inside living cells with fluorescence microscopy

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

Natural gut molecule reverses liver damage and repairs gut lining

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

Promising treatment slows liver cancer by inhibiting fat enzyme

Promising new treatment helps the immune system attack and destroy liver tumors

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

Rising liver cancer rates highlight need for urgent action worldwide

Substance use disorders increase risk of unplanned hospital readmissions

Pharmaceutical Manufacturing - Industry Focus eBook eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Fatty Liver

Overview

Latest Fatty Liver News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Newsletters you may be interested in