Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Lightly roasted coffee: Benefits for overweight individuals

Study found that consuming lightly roasted coffee rich in polyphenols significantly reduced body fat percentage and modestly increased muscle mass in overweight or obese individuals.

1 Sep 2024

EU-funded MASTER project develops first comprehensive database of food metagenomes

The first comprehensive database of food metagenomes has been developed by the EU-funded MASTER project.

30 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Preventing the spread of superbugs in aged care facilities

There's an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic-resistant bacteria or 'superbugs', researchers from Flinders University and SAHMRI warn.

29 Aug 2024

$120 million gift boosts UCLA’s efforts in immunotherapy and innovation

UCLA has received a $120 million commitment from surgeon, inventor and philanthropist Dr. Gary Michelson and his wife, Alya, to kick-start the California Institute for Immunology and Immunotherapy, an innovative public-private partnership aimed at spurring breakthrough discoveries that prevent and cure diseases and catalyze economic growth and innovation in Los Angeles.

27 Aug 2024

Gut microbiota plays a critical role in rotavirus vaccine efficacy

Certain types of gut bacteria can hinder the efficacy of the rotavirus vaccine, according to researchers at the Institute for Biomedical Sciences at Georgia State University.

27 Aug 2024

Should extremely preterm infants be given probiotics?

Researchers found that probiotics similarly impact the gut microbiome in extremely preterm infants as in very preterm infants, suggesting potential benefits for NEC prevention, but further research is needed.

26 Aug 2024

Exploring early detection of Alzheimer's disease through non-cognitive symptoms

The article presents a thorough examination of Alzheimer's disease (AD), emphasizing early detection as critical due to the disease's progression through stages from normal cognition to mild cognitive impairment (MCI) and eventually dementia.

26 Aug 2024

How diet shapes gut microbiota and affects brain function

Researchers discuss the diet-microbiota-gut-brain axis, which describes the role of both diet and gut microbiota composition on cognitive and emotional health.

26 Aug 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

Human gut microbiome: A source of new antibiotic peptides

Researchers identified 323 peptide-based antimicrobials from the human microbiome, with 71% showing significant antibacterial activity, and the lead peptide, prevotellin-2, matching the efficacy of polymyxin B in both in vitro and in vivo models.

25 Aug 2024

Advances in endoscopic treatment for inflammatory bowel disease complications

Inflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions affecting the gastrointestinal tract.

23 Aug 2024

Maternal gut bacteria linked to changes in fetal brain metabolism

The impact of Bifidobacterium breve's presence in the maternal gut during pregnancy on fetal brain metabolism.

23 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

Rising IBD incidence highlights need for non-invasive biomarkers in diagnosis

The global burden of inflammatory bowel diseases (IBD), primarily Crohn's disease (CD) and ulcerative colitis (UC), continues to rise. Recent data show incidence rates of up to 17.8 cases per 100,000 person-years for CD and even higher for UC, reaching 28.4 per 100,000 person-years. These diseases primarily affect older populations and vary geographically, with higher prevalence rates in highly developed countries.

23 Aug 2024

SCARB2 deficiency disrupts bile acid metabolism and gut microbiome

The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut microbiome. This disruption affects the signaling pathway involving FXR, which normally regulates bile acid synthesis and intestinal lipid absorption. The hyperactive FXR in Scarb2-deficient mice leads to a decrease in epithelial cell turnover and lipid malabsorption, particularly impacting the absorption of vitamin E, which is crucial for maintaining neurological health. The researchers further explored the impact of these changes on the gut-liver axis and found alterations in the expression of genes related to bile acid synthesis.

23 Aug 2024

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Lightly roasted coffee: Benefits for overweight individuals

EU-funded MASTER project develops first comprehensive database of food metagenomes

Study reveals key role of A20 protein in controlling inflammation in liver disease

Preventing the spread of superbugs in aged care facilities

$120 million gift boosts UCLA’s efforts in immunotherapy and innovation

Gut microbiota plays a critical role in rotavirus vaccine efficacy

Should extremely preterm infants be given probiotics?

Exploring early detection of Alzheimer's disease through non-cognitive symptoms

How diet shapes gut microbiota and affects brain function

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Human gut microbiome: A source of new antibiotic peptides

Advances in endoscopic treatment for inflammatory bowel disease complications

Maternal gut bacteria linked to changes in fetal brain metabolism

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Rising IBD incidence highlights need for non-invasive biomarkers in diagnosis

SCARB2 deficiency disrupts bile acid metabolism and gut microbiome

Mother's gut bacteria during pregnancy promote healthy brain development in the fetus

Understanding gluten's role in autoimmunity and inflammation

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Fasting and ketogenic diet reveal new vulnerability of pancreatic tumors to existing cancer drug

Your full guide to the gut microbiome eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Your full guide to the gut microbiome eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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