Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

GS-9620 therapy suppresses hepatitis B virus infection

A novel drug developed by Gilead Sciences and tested in an animal model at the Texas Biomedical Research Institute in San Antonio suppresses hepatitis B virus infection by stimulating the immune system and inducing loss of infected cells.

29 Apr 2013

New clinical algorithm to treat complex pediatric patients with ARPKD

A collaborative team of physician-scientists at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease.

29 Apr 2013

Pfizer reports that Prevenar 13 Phase 3 study meets all primary, secondary objectives

Pfizer Inc. presented today the results from a Phase 3 study investigating immunogenicity, tolerability and safety of Prevenar 13 (Pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]) in adults 18 to 49 years of age.

From Pfizer, Inc. 29 Apr 2013

New technologies speed health care delivery, reduce costs, pioneer new therapies

The current special issue of Technology and Innovation - Proceedings of the National Academy of Inventors, devoted to studies on medical technology and health care delivery, focuses on a wide range of topics, from new technologies to reduce the cost of health care to understanding the human microbiome.

25 Apr 2013

Schizophrenia cardiovascular risk under-recognized in primary care

UK researchers have found that despite being a major contributor to premature deaths among patients with schizophrenia, cardiovascular disease is less likely to be recorded on their primary care records than people without schizophrenia.

25 Apr 2013

Higher TMAO blood levels linked to increased risk of heart disease

A microbial byproduct of intestinal bacteria contributes to heart disease and serves as an accurate screening tool for predicting future risks of heart attack, stroke and death in persons not otherwise identified by traditional risk factors and blood tests, according to Cleveland Clinic research published today in The New England Journal of Medicine.

25 Apr 2013

Sofosbuvir is safer than interferon for hepatitis C patients, say scientists

A new drug is offering dramatic cure rates for hepatitis C patients with two subtypes of the infection -- genotype 2 and 3, say a team of scientists led by Weill Cornell Medical College researchers.

25 Apr 2013

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States Food and Drug Administration has approved Sucampo's supplemental new drug application for AMITIZA (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation in adult patients with chronic, non-cancer pain.

24 Apr 2013

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

Janssen R&D Ireland today announced primary efficacy and safety results from two global Phase 3 studies demonstrating that use of the investigational protease inhibitor simeprevir (TMC435) led to sustained virologic response 12 weeks after the end of treatment (SVR12) in 80 and 81 percent, respectively, of treatment-naive genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin.

24 Apr 2013

New screening method detects ovarian cancer by examining neighboring cells

Pioneering biophotonics technology developed at Northwestern University is the first screening method to detect the early presence of ovarian cancer in humans by examining cells easily brushed from the neighboring cervix or uterus, not the ovaries themselves.

23 Apr 2013

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Gilead Sciences, Inc. today announced that detailed results from four Phase 3 clinical trials (NEUTRINO, FISSION, POSITRON and FUSION) evaluating sofosbuvir, the company's investigational once-daily nucleotide NS5B inhibitor for the treatment of chronic hepatitis C virus infection, will be presented this week in oral sessions at the 48th Annual Meeting of the European Association for the Study of the Liver in Amsterdam, The Netherlands.

23 Apr 2013

Circumcision lowers bacterial load, possibly allowing for HIV infection risk reduction, researchers say

"Circumcision reduces a man's risk of acquiring and transmitting HIV and other sexually transmitted diseases, and now researchers have found a possible explanation: the procedure reduces the quantity and diversity of bacteria at the head of the penis," the New York Times' "Well" blog reports (Bakalar, 4/18).

20 Apr 2013

Research findings describe specific profile of patients with ACLF

In this prospective study, led by Dr Richard Moreau, INSERM Research Director (Mixed Research Unit 773 "Centre de Recherche biom-dicale Bichat-Beaujon"; INSERM/Universit- Paris Diderot) who is also a practitioner attached to the Hepatology Department of the Beaujon Hospital (AP-HP), researchers studied a cohort of 1343 patients from 12 European countries.

20 Apr 2013

Parents tend to share more bacteria with their dogs than their children

As much as dog owners love their children, they tend to share more of themselves, at least in terms of bacteria, with their canine cohorts rather than their kids.

18 Apr 2013

Dr. Jeffrey Maisels honored as 2013 Legends of Neonatology Hall of Fame inductee

M. Jeffrey Maisels, M.D., was honored as a 2013 Legends of Neonatology Hall of Fame inductee. He was chosen for a career spanning 47 years of clinical care and research involving management of the jaundiced newborn infant.

18 Apr 2013

Research shows how climate, environmental changes influence spread of dangerous viruses

How are human and animal diseases in general affected by the climate becoming "wilder, wetter and warmer"? Solveig Jore's doctoral research shows that the tick Ixodes ricinus has spread over larger geographical areas in Norway and that climate and environmental changes, access to host animals and demography affect tick distribution in Norway.

17 Apr 2013

Circumcision offers men some protection against HIV, discovers TGen-led study

Male circumcision reduces the abundance of bacteria living on the penis and might help explain why circumcision offers men some protection against HIV, according to a study led by the Translational Genomics Research Institute.

17 Apr 2013

Adult male circumcision reduces bacteria living on penis, study shows

Circumcision drastically alters the microbiome of the penis, changes that could explain why circumcision offers protection against HIV and other viral infections.

17 Apr 2013

COPD phase III study by Almirall and Forest Laboratories announces positive results

Almirall, S.A. (ALM:MC) and Forest Laboratories, Inc. (NYSE:FRX) today announced positive topline results from a six month pivotal phase III clinical trial evaluating the efficacy and safety of fixed dose combinations of aclidinium bromide (LAMA) and formoterol fumarate (LABA) delivered by Almirall’s inhaler Genuair® (Pressair™ in the USA).

16 Apr 2013

Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

Rhythm announced today the initiation of an additional Phase 2 clinical trial for RM-131, the company's novel ghrelin agonist, for the treatment of chronic constipation. Ghrelin is a peptide hormone produced in the stomach that stimulates gastrointestinal motility.

16 Apr 2013

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

GS-9620 therapy suppresses hepatitis B virus infection

New clinical algorithm to treat complex pediatric patients with ARPKD

Pfizer reports that Prevenar 13 Phase 3 study meets all primary, secondary objectives

New technologies speed health care delivery, reduce costs, pioneer new therapies

Schizophrenia cardiovascular risk under-recognized in primary care

Higher TMAO blood levels linked to increased risk of heart disease

Sofosbuvir is safer than interferon for hepatitis C patients, say scientists

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

New screening method detects ovarian cancer by examining neighboring cells

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Circumcision lowers bacterial load, possibly allowing for HIV infection risk reduction, researchers say

Research findings describe specific profile of patients with ACLF

Parents tend to share more bacteria with their dogs than their children

Dr. Jeffrey Maisels honored as 2013 Legends of Neonatology Hall of Fame inductee

Research shows how climate, environmental changes influence spread of dangerous viruses

Circumcision offers men some protection against HIV, discovers TGen-led study

Adult male circumcision reduces bacteria living on penis, study shows

COPD phase III study by Almirall and Forest Laboratories announces positive results

Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

Industry Focus eBook - Microbiology (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Industry Focus eBook - Microbiology (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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