Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

AstraZeneca commences NKTR-118 Phase III clinical programme for opioid-induced constipation

AstraZeneca today announced enrolment of the first patient in the Phase III clinical programme for NKTR-118, an oral peripherally-acting opioid antagonist being investigated for the treatment of opioid-induced constipation (OIC).

16 Mar 2011

Hydro-stomach CT imaging is not a reliable tool for EGC detection: Study

Traditionally, both air and tap water have been used as oral contrast agents to achieve adequate gastric distension for preoperative computed tomography imaging in patients with early gastric cancer.

16 Mar 2011

Study underscores need for monitoring vitamin D levels in all cirrhosis patients

Vitamin D deficiency is a well reported complication in chronic cholestatic liver disease such as primary biliary cirrhosis. While the prevalence and treatment of this deficiency has been addressed in many articles over the last decades, little is known of the vitamin D status in alcoholic liver cirrhosis.

16 Mar 2011

Repligen reports positive results from RG1068 Phase 3 study to improve MRI of the pancreas

Repligen Corporation reported today positive top-line results from a Phase 3 study to evaluate the safety and efficacy of RG1068, synthetic human secretin, to improve magnetic resonance imaging (MRI) of the pancreas in patients with pancreatic disease using endoscopy (ERCP) as a diagnostic reference.

14 Mar 2011

Life Technologies receives FDA 510(k) clearance for StemPro MSC SFM device

Life Technologies Corporation today announced it has received FDA 510(k) clearance for StemPro MSC SFM – a first for this next-generation stem cell culture medium that is now cleared as a medical device and satisfies a crucial requirement for researchers involved in clinical trials in the United States.

14 Mar 2011

Specialists to provide update on latest advancements in surgical field at UCSD conference

The Department of Surgery at the University of California, San Diego School of Medicine will host the 34th San Diego Postgraduate Assembly in Surgery. The event will take place March 17 to 19, 2011 at the Omni San Diego Hotel.

14 Mar 2011

New study: Alcohol-related chronic pancreatitis is lower than other causes

The relative rate of alcohol-related chronic pancreatitis is lower when compared to other causes, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association Institute.

14 Mar 2011

Scientists discover four new genetic variants in humans linked with NAFLD

Five genetic variants in humans - four new - associate with Nonalcoholic Fatty Liver Disease, according to a study published March 10 in PLoS Genetics.

10 Mar 2011

AGA issues Medical Position Statement on Treatment of Barrett's Esophagus

BARRX Medical, Inc., a leader in developing minimally invasive medical devices to remove precancerous tissue from the gastrointestinal tract, reported today that the American Gastroenterological Association has issued the AGA Medical Position Statement on the Treatment of Barrett's Esophagus.

10 Mar 2011

Despite aspirin therapy, specific inflammatory pathways may influence risk of colorectal cancer

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood.

10 Mar 2011

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood.

10 Mar 2011

Vertex to present telaprevir and VX-222 study results against hepatitis C at EASL annual meeting

Vertex Pharmaceuticals Incorporated announced today that 15 abstracts on the company's medicines in development for hepatitis C, including its protease inhibitor, telaprevir, and polymerase inhibitor, VX-222, were accepted for presentation at the 46th Annual Meeting of the European Association for the Study of the Liver in Berlin, Germany, March 30 to April 3, 2011.

9 Mar 2011

Oral magnesium oxide is a safe treatment for children with chronic constipation

Magnesium-containing cathartics are commonly used to treat chronic constipation. Although hypermagnesemia is a rare clinical condition, it can occur as a side effect of increased intake of magnesium salts.

9 Mar 2011

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced that several new data analyses from Phase III studies of VICTRELIS, its investigational oral hepatitis C protease inhibitor, will be presented at The International Liver CongressTM / 46th European Association for the Study of the Liver annual meeting.

9 Mar 2011

First urinary metabolomic investigation in gastric cancer using gas chromatography/mass spectrometry

Metabolomics is a post-genomic research field for analysis of low molecular weight compounds in biological systems, and its approaches offer an analysis of metabolite level changes in biological samples. Recently, metabolomic method has shown great potentials in identifying the new diagnostic markers and therapeutic targets for cancers. However, metabolomic studies on cancer metastasis remain scarce.

9 Mar 2011

Autoimmune response mediated by T lymphocytes may play vital role in pathogenesis of biliary atresia

Biliary atresia (BA) is an inflammatory obliterative cholangiopathy with unknown etiology, leading to progressive fibrosis and cirrhosis. Microarray technology, emerged as an indispensable research tool for gene expression profiling, has been used to study the mechanism underlying BA, and allows the simultaneous analysis of thousands of transcripts within a single experiment.

9 Mar 2011

Study: HBV infection reduces risk of liver metastasis in CRC patients

Colorectal cancer is the second leading cause of cancer-related deaths in Western countries. Metastatic liver disease more frequently develops metachronous metastasis following treatment of CRC.

9 Mar 2011

UTHealth study: Children with H. pylori infection have lower levels of iron

Children without previous iron deficiencies or anemia who remained infected with Helicobacter pylori had significantly lower levels of iron compared to children who had the infection eradicated, according to researchers at The University of Texas Health Science Center at Houston.

8 Mar 2011

Top-line results from Repligen RG2417 Phase 2b trial results in patients with bipolar depression

Repligen Corporation announced today results of a Phase 2b clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression.

8 Mar 2011

Scientists identify regulatory T cells responsible for limiting immune response

Scientists from the Walter and Eliza Hall Institute have identified the key immune cell population responsible for regulating the body's immune response.

6 Mar 2011

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

AstraZeneca commences NKTR-118 Phase III clinical programme for opioid-induced constipation

Hydro-stomach CT imaging is not a reliable tool for EGC detection: Study

Study underscores need for monitoring vitamin D levels in all cirrhosis patients

Repligen reports positive results from RG1068 Phase 3 study to improve MRI of the pancreas

Life Technologies receives FDA 510(k) clearance for StemPro MSC SFM device

Specialists to provide update on latest advancements in surgical field at UCSD conference

New study: Alcohol-related chronic pancreatitis is lower than other causes

Scientists discover four new genetic variants in humans linked with NAFLD

AGA issues Medical Position Statement on Treatment of Barrett's Esophagus

Despite aspirin therapy, specific inflammatory pathways may influence risk of colorectal cancer

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

Vertex to present telaprevir and VX-222 study results against hepatitis C at EASL annual meeting

Oral magnesium oxide is a safe treatment for children with chronic constipation

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

First urinary metabolomic investigation in gastric cancer using gas chromatography/mass spectrometry

Autoimmune response mediated by T lymphocytes may play vital role in pathogenesis of biliary atresia

Study: HBV infection reduces risk of liver metastasis in CRC patients

UTHealth study: Children with H. pylori infection have lower levels of iron

Top-line results from Repligen RG2417 Phase 2b trial results in patients with bipolar depression

Scientists identify regulatory T cells responsible for limiting immune response

Microbiology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Microbiology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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