Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Cirrhosis patients with low musle mass more apt to die

Medical researchers at the University of Alberta reviewed the medical records of more than 100 patients who had a liver scarring condition and discovered those who were losing muscle were more apt to die while waiting for a liver transplant. These cirrhosis patients were placed at a lower spot on the transplant list because they had a higher functioning liver and were seemingly less sick than others with the same condition, based on scoring systems physicians commonly use today.

8 Feb 2012

Takeda launches EDARBYCLOR in the U.S. for treatment of hypertension

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., announced EDARBYCLOR (azilsartan medoxomil and chlorthalidone) is now available by prescription in U.S. pharmacies for the treatment of hypertension to lower blood pressure in adults.

6 Feb 2012

Binge drinking and moderate drinking do not differ in risk for ischemic heart disease or mortality

Most studies have found that binge drinking is associated with a loss of alcohol's protective effect against ischemic heart disease (IHD) and most studies have found an increase of coronary risk among binge drinkers.

3 Feb 2012

$Heart burn drugs and hip fractures in postmenopausal women smokers: Study establishes link$

Heart burn drugs and hip fractures in postmenopausal women smokers: Study establishes link

A new study shows that postmenopausal women with a history of smoking who take heartburn drugs called proton pump inhibitors (PPIs) for two years or longer may be more likely to sustain a hip fracture. The risk rises with longer use say researchers. But the risk does disappear after women stop taking these drugs for two years. Further women who never smoked were not at increased risk for hip fracture even if they took PPIs regularly, the study showed. The new findings appear in the journal BMJ.

2 Feb 2012

Takeda, SPI announce that lubiprostone phase 3 trial on OBD meets primary endpoint

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that lubiprostone met the primary endpoint in a phase 3 clinical trial for the treatment of opioid-induced bowel dysfunction (OBD) in patients with chronic, non-cancer pain, excluding those taking methadone.

2 Feb 2012

Study identifies norovirus as major cause of all infection outbreaks in U.S. hospitals

Norovirus, a pathogen that often causes food poisoning and gastroenteritis, was responsible for 18.2 percent of all infection outbreaks and 65 percent of ward closures in U.S. hospitals during a two-year period, according to a new study published in the February issue of the American Journal of Infection Control (AJIC), the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

1 Feb 2012

Novartis' Gleevec receives FDA approval for use in patients with CD117-positive GIST

The U.S. Food and Drug Administration today granted Gleevec (imatinib) regular approval for use in adult patients following surgical removal of CD117-positive gastrointestinal stromal tumors.

1 Feb 2012

Tobacco smoking may increase risk of esophageal cancer in Barrett's patients

Barrett's esophagus (BE) patients who smoke tobacco are at a two-fold increased risk of developing esophageal cancer, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. BE patients who smoke also double their risk for developing advanced precancerous cells.

31 Jan 2012

Study: Live liver donor transplantation safer than previously believed

People who donate a portion of their livers for transplant to a relative or friend whose liver is failing can generally expect to live long, healthy lives and recover safely from the donation surgery, Johns Hopkins researchers have found.

27 Jan 2012

Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

Major surgery to donate a portion of liver does not interfere with long, healthy life

26 Jan 2012

Heartburn drugs ineffective in kids with asthma: Study

A drug used to treat acid reflux has often been used for hard-to-treat asthma. A new study finds that it does not help children with the breathing disease and may cause side effects.

24 Jan 2012

Pernix obtains marketing rights to new gastroenterology product in the U.S.

Pernix Therapeutics Holdings, Inc., a specialty pharmaceutical company, today announced it has entered into a license and supply agreement with a private company for a new FDA-approved prescription product to treat gastroenterology disease.

24 Jan 2012

Researchers evaluate colonoscopy quality performance and reporting in daily practice

Researchers in the Netherlands assessed the quality of colonoscopy reporting in daily clinical practice and evaluated the quality of colonoscopy performance. They found that colonoscopy reporting varied significantly in clinical practice.

24 Jan 2012

High-fiber diet may raise risk of diverticulosis

For more than 40 years, scientists and physicians have thought eating a high-fiber diet lowered a person's risk of diverticulosis, a disease of the large intestine in which pouches develop in the colon wall. A new study of more than 2,000 people reveals the opposite may be true.

24 Jan 2012

Luteolin interferes with cell signaling in colon cancer cells

Luteolin is a flavonoid commonly found in fruit and vegetables. This compound has been shown in laboratory conditions to have anti-inflammatory, anti-oxidant and anti-cancer properties but results from epidemiological studies have been less certain. New research published in BioMed Central's open access journal BMC Gastroenterology shows that luteolin is able to inhibit the activity of cell signaling pathways (IGF and PI3K) important for the growth of cancer in colon cancer cells.

23 Jan 2012

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

MSD today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending the use of REMICADE (infliximab) in the treatment of severely active ulcerative colitis (UC) in pediatric patients ages 6 to 17 years, who have had an inadequate response to conventional therapy, including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies.

21 Jan 2012

FDA allows marketing of Stratify JCV Antibody ELISA test for PML

Today, the U.S. Food and Drug Administration allowed marketing of the first test to help determine the risk for a rare brain infection called progressive multifocal leukoencephalopathy (PML) in people using the drug Tysabri (natalizumab) to treat multiple sclerosis (MS) or Crohn's disease.

21 Jan 2012

New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced updated data from the Phase 1b portion of an ongoing Phase 1b/2 clinical trial of saridegib in combination with the chemotherapy gemcitabine in patients with previously untreated, metastatic pancreatic cancer.

20 Jan 2012

Inflammation enhances pancreatic cancer cell progression

Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab, discovered that pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected.

20 Jan 2012

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Cirrhosis patients with low musle mass more apt to die

Takeda launches EDARBYCLOR in the U.S. for treatment of hypertension

Binge drinking and moderate drinking do not differ in risk for ischemic heart disease or mortality

Heart burn drugs and hip fractures in postmenopausal women smokers: Study establishes link

Takeda, SPI announce that lubiprostone phase 3 trial on OBD meets primary endpoint

Study identifies norovirus as major cause of all infection outbreaks in U.S. hospitals

Novartis' Gleevec receives FDA approval for use in patients with CD117-positive GIST

Tobacco smoking may increase risk of esophageal cancer in Barrett's patients

Study: Live liver donor transplantation safer than previously believed

Strong link between high HuR protein levels and malignancy of HCC

Major surgery to donate a portion of liver does not interfere with long, healthy life

Heartburn drugs ineffective in kids with asthma: Study

Pernix obtains marketing rights to new gastroenterology product in the U.S.

Researchers evaluate colonoscopy quality performance and reporting in daily practice

High-fiber diet may raise risk of diverticulosis

Luteolin interferes with cell signaling in colon cancer cells

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

FDA allows marketing of Stratify JCV Antibody ELISA test for PML

New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer

Inflammation enhances pancreatic cancer cell progression

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Microbiology eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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