Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Concomitant use of dexlansoprazole and other PPIs with Plavix: TGRD U.S. initiates trial

Takeda Global Research & Development Center, Inc., U.S., (TGRD U.S.) announced today that it has initiated a trial to study how dexlansoprazole and several other proton pump inhibitors (PPIs) affect the pharmacokinetics and pharmacodynamics of Plavix (clopidogrel bisulfate) in healthy subjects. Takeda has been evaluating all published data and communications from the U.S. Food and Drug Administration (FDA) regarding the potential risks associated with concomitant use of clopidogrel and PPIs.

10 Feb 2010

Study provides new data about potential risk of gastric cancer in patients with intestinal metaplasia

Gastric cancer remains a significant problem globally. The relationship between intestinal metaplasia (IM) and gastric cancer has always been controversial. Generally IM is divided into subtypes on the basis of histochemical characteristics; however, this classification is confusing.

10 Feb 2010

Study explores link between HBV genotype C and liver cirrhosis

Hepatitis B virus (HBV) genotypes have distinct geographical distributions, and have been shown to differ with regard to clinical outcome and prognosis. However, the relationship between HBV genotypes and liver cirrhosis remains controversial and no study on exploring the association between HBV genotypes and subclinical cirrhosis in community-based population has been reported.

10 Feb 2010

Elan announces fourth-quarter and full-year financial results ended December 31, 2009

Elan Corporation, plc today reported its fourth quarter and full-year 2009 financial results and provides financial guidance for 2010.

10 Feb 2010

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Helicobacter pylori (H. pylori) are considered to be the most important etiological agents of chronic gastritis. The eradication of H. pyloridepends on the combination of antibiotics and acid suppression drugs.

10 Feb 2010

Data provide key information about epigenetic profiles for gastric cancer

Gastric cancer, one of the most common types of cancer, is associated with high mortality rates. In the last decades, a decrease in the worldwide incidence has been observed with some changes in the therapeutic and diagnostic options.

10 Feb 2010

TI commences Phase IIa clinical trial for its lead molecule in CDH

Trigemina, Inc. (TI), a Mountain View based startup, has begun a Phase IIa clinical trial for its lead molecule in Chronic Daily Headache (CDH) in collaboration with Dr. Egilius Spierings at MedVadis Research Corporation located outside of Boston.

10 Feb 2010

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

Previous studies have shown that assessment of immunoglobulin subclasses in plasma cells by immunohistochemistry (IHC) may be useful in the histopathologic evaluation of autoimmune liver diseases. However, further studies are necessary in order to validate the diagnostic utility of IgM and IgG immunohistochemistry in this specific scenario.

10 Feb 2010

Leading researchers discuss latest breakthroughs and best forms of cancer prevention

Eating a balanced diet and preparing your food in the correct way may be your best defense against developing cancer, according to top cancer researchers

9 Feb 2010

Thymosin β4 exhibits potential as new therapeutic agent for liver failure due to chronic HBV infection

REGENERX BIOPHARMACEUTICALS, INC. announced today that researchers have correlated Tβ4 levels with the clinical course of patients with hepatitis B virus-related liver failure. It was reported that serum thymosin β4 levels were significantly lower in patients with chronic hepatitis B infection and that the magnitude of the reduction of thymosin β4 was closely related to the severity of the hepatic injury and to patient death. Since patients with higher Tβ4 levels survived the disease, changes in Tβ4 values could reflect outcome in some liver failure patients.

9 Feb 2010

A novel way to identify color choice in healthy, anxious and depressed individuals

People with anxiety and depression are most likely to use a shade of gray to represent their mental state. Researchers writing in the open access journal BMC Medical Research Methodology describe the development of a color chart, The Manchester Color Wheel, which can be used to study people's preferred pigment in relation to their state of mind.

9 Feb 2010

Study may provide new intervention strategies for esophageal adenocarcinoma

Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus.

6 Feb 2010

Study suggests environmental factors play a significant role in the etiology of Crohn's disease

Although inflammatory bowel disease (IBD) [comprising mainly Crohn's disease (CD) and ulcerative colitis (UC)] is thought to affect about 150 000 people in the United Kingdom, the prevalence of severe IBD is not known. Mortality following hospitalization for IBD is significant but little has been reported on long-term follow-up.

6 Feb 2010

Endoscopic surveillance could be an appropriate strategy for subepithelial lesions

Although several studies pertaining to the natural history of subepithelial tumors have been published, they have been limited by small sample size and relatively short follow-up. The natural history of subepithelial lesions has not been clearly elucidated, and the appropriate management strategy for small subepithelial tumors is still controversial.

6 Feb 2010

CREON effective in improving CFA and CNA in pediatric patients with EPI due to CF

Solvay Pharmaceuticals, Inc. announced that Phase IIIb data published in the January issue of Clinical Therapeutics confirm that CREON® (pancrelipase) Delayed-Release Capsules significantly improves a key measure of fat absorption in children aged 7-11 years who have exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF), EPI is a condition resulting from a deficiency in the production and/or secretion of pancreatic enzymes that are necessary to digest nutrients in food.

5 Feb 2010

Survey finds majority of patients are interested in video recording of colonoscopy procedure

Colonoscopy is operator-dependent and substantial numbers of pre-cancerous polyps are missed during colonoscopy. Colonoscopies are often poorly documented, with only a few still photographs taken of anatomic landmarks and abnormal findings.

5 Feb 2010

NIH panel convened to increase the use and quality of colorectal cancer screening in the U.S.

Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Despite evidence and guidelines supporting the value of screening for this disease, rates of screening for colorectal cancer are consistently lower than those for other types of cancer, particularly breast and cervical.

5 Feb 2010

Researchers evaluate ethical and legal issues of volunteers who participate in endoscopy-based studies

The involvement of healthy volunteers (HV) in clinical and preclinical research, especially in the gastroenterology, has grown dramatically over the past few years. However, many issues of ethical, methodological or even legal concerns have not been systematically studied.

5 Feb 2010

Use of laparoscopic hepatectomy in treating HCC patients achieves complete resection

Conventional hepatectomy is an effective way to treat hepatocellular carcinoma (HCC). However, it is invasive and stressful. Laparoscopic surgery, a kind of minimally invasive surgery, has recently gained considerable advances.

5 Feb 2010

New research may help adopt acupuncture as a treatment option for NHS patients

Important new research about the effects of acupuncture on the brain may provide an understanding of the complex mechanisms of acupuncture and could lead to a wider acceptability of the treatment.

4 Feb 2010

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Concomitant use of dexlansoprazole and other PPIs with Plavix: TGRD U.S. initiates trial

Study provides new data about potential risk of gastric cancer in patients with intestinal metaplasia

Study explores link between HBV genotype C and liver cirrhosis

Elan announces fourth-quarter and full-year financial results ended December 31, 2009

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Data provide key information about epigenetic profiles for gastric cancer

TI commences Phase IIa clinical trial for its lead molecule in CDH

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

Leading researchers discuss latest breakthroughs and best forms of cancer prevention

Thymosin β4 exhibits potential as new therapeutic agent for liver failure due to chronic HBV infection

A novel way to identify color choice in healthy, anxious and depressed individuals

Study may provide new intervention strategies for esophageal adenocarcinoma

Study suggests environmental factors play a significant role in the etiology of Crohn's disease

Endoscopic surveillance could be an appropriate strategy for subepithelial lesions

CREON effective in improving CFA and CNA in pediatric patients with EPI due to CF

Survey finds majority of patients are interested in video recording of colonoscopy procedure

NIH panel convened to increase the use and quality of colorectal cancer screening in the U.S.

Researchers evaluate ethical and legal issues of volunteers who participate in endoscopy-based studies

Use of laparoscopic hepatectomy in treating HCC patients achieves complete resection

New research may help adopt acupuncture as a treatment option for NHS patients

Pittcon Keynote Speaker Highlights eBook

Evolving spectrophotometry for modern biopharma workflows

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Fluidics in Modern Healthcare & Medical Device Innovation

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Pittcon Keynote Speaker Highlights eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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