Gene News and Research

Latest Gene News and Research

Engineered blood vessel cells boost islet transplant success in diabetes treatment

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine investigators.

21 Feb 2025

Characterizing the spectrum of mitochondrial DNA deletion disease syndromes

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA deletion disease syndromes.

21 Feb 2025

Antioxidant-enzyme interactions and their role in non-communicable diseases

Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the development of non-communicable diseases (NCDs).

21 Feb 2025

Targeting FGFR mutations offers new hope for bone repair in skeletal disorders

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect craniofacial and mandibular development.

21 Feb 2025

LUC7 proteins play crucial role in efficient RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

New robotic surgery device aims to enhance precision in retinal procedures

When even the most highly trained surgeons perform procedures on the retina-one of the smallest, most delicate parts of the human body-the stakes are high.

21 Feb 2025

Study links fetal acetaminophen exposure to increased risk of ADHD

Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder (ADHD), according to a study published Feb. 6 in Nature Mental Health.

21 Feb 2025

Boston University professor receives grant for preeclampsia drug discovery research

Wendy Kuohung, MD, associate professor of obstetrics & gynecology at Boston University Chobanian & Avedisian School of Medicine, has been awarded a two-year, Discovery Research Grant from March of Dimes.

21 Feb 2025

Breakthrough discovery unveils potential treatment for hepatitis B

In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, research led by Memorial Sloan Kettering Cancer Center (MSK), Weill Cornell Medicine and The Rockefeller University identified a vulnerability that opens the door to new treatments.

20 Feb 2025

Scientists uncover hidden genetic causes of congenital heart disease

Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.

20 Feb 2025

Long-term grape consumption shown to improve muscle health in both men and women

A new study from Western New England University (WNE) has revealed that long-term grape consumption significantly impacts muscle health, with notable benefits for both men and women.

20 Feb 2025

Inhalable gene therapy tested for cystic fibrosis treatment in the UK and Europe

An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis, irrespective of their mutation type, is being tested in human trials in the UK and Europe.

20 Feb 2025

Study shows how exercise counteracts stress-induced high blood pressure

Chronic stress raises blood pressure. New research from Juntendo University, Japan, reveals that voluntary exercise prevents hypertension (high blood pressure) by restoring STAT3 levels in the amygdala.

20 Feb 2025

Unfolded protein response disruptions contribute to colorectal cancer and gut-related disorders

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

20 Feb 2025

Epigenetic inhibitors show promise in malaria treatment

Epigenetic inhibitors as a promising new antimalarial intervention strategy? A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen.

20 Feb 2025

First prenatal treatment for spinal muscular atrophy shows promising results

Spinal muscular atrophy (SMA) is a progressive neurodegenerative disorder set in motion before birth. Scientists at St. Jude Children's Research Hospital led the first in uterotreatment of SMA with the orally administered drug risdiplam.

20 Feb 2025

Breakthrough in gene therapy could help protect against heart arrhythmias

Cardiac arrhythmias affect millions across the world and are responsible for a fifth of all deaths in the Netherlands.

20 Feb 2025

Innovative method improves understanding of cellular and molecular mechanisms in kidney diseases

Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic kidney disease (CKD), at both the cellular and molecular levels.

19 Feb 2025

Newly discovered antigens could speed the development of potent cancer immunotherapies

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

19 Feb 2025

Cancer cells cooperate to source nutrients and support tumor growth

Cancer cells work together to source nutrients from their environment-a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

19 Feb 2025

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Gene News and Research

Latest Gene News and Research

Engineered blood vessel cells boost islet transplant success in diabetes treatment

Characterizing the spectrum of mitochondrial DNA deletion disease syndromes

Antioxidant-enzyme interactions and their role in non-communicable diseases

Targeting FGFR mutations offers new hope for bone repair in skeletal disorders

LUC7 proteins play crucial role in efficient RNA splicing

New robotic surgery device aims to enhance precision in retinal procedures

Study links fetal acetaminophen exposure to increased risk of ADHD

Boston University professor receives grant for preeclampsia drug discovery research

Breakthrough discovery unveils potential treatment for hepatitis B

Scientists uncover hidden genetic causes of congenital heart disease

Long-term grape consumption shown to improve muscle health in both men and women

Inhalable gene therapy tested for cystic fibrosis treatment in the UK and Europe

Study shows how exercise counteracts stress-induced high blood pressure

Unfolded protein response disruptions contribute to colorectal cancer and gut-related disorders

Epigenetic inhibitors show promise in malaria treatment

First prenatal treatment for spinal muscular atrophy shows promising results

Breakthrough in gene therapy could help protect against heart arrhythmias

Innovative method improves understanding of cellular and molecular mechanisms in kidney diseases

Newly discovered antigens could speed the development of potent cancer immunotherapies

Cancer cells cooperate to source nutrients and support tumor growth

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