Gene News and Research

Latest Gene News and Research

Aspartame triggers genetic changes tied to glioblastoma severity

Study shows aspartame affects gut microbiome and gene expression in glioblastoma, highlighting potential links to cancer progression and treatment strategies.

8 Jul 2025

Landmark discovery reshapes understanding of key cancer protein MCL-1

Landmark research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some promising cancer treatments are causing serious side effects, and offers a roadmap for designing safer, more targeted therapies.

8 Jul 2025

New gene editing approach targets mutation behind common genetic heart disease

Fourteen million people worldwide suffer from enlarged hearts, or hypertrophic cardiomyopathy (HCM), a genetic disease that thickens the heart's walls, making it harder for the organ to pump blood - but many of them don't know it.

8 Jul 2025

Developmental timing shapes fluoxetine’s effects on brain energy and mood behavior

Researchers have found that the timing of when fluoxetine (commonly known by its brand name, Prozac) is administered is vital in determining the impact it has on long-lasting mood behavior and accompanying changes in the prefrontal cortex.

7 Jul 2025

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases.

7 Jul 2025

Reversing immune fatigue offers new hope for cancer treatment

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

7 Jul 2025

Synthetic Biology and the Pursuit of Living Diagnostics and Therapeutics

In this interview, Professor James J. Collins, founder of the field of Synthetic Biology, discusses his journey to founding the field of synthetic biology and the potential of living diagnostics.

From Pittcon 7 Jul 2025

ADA2 regulates inflammation through lysosomal and extracellular mechanisms

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and activation.

7 Jul 2025

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs).

7 Jul 2025

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

By using a genetic technique developed at UT Southwestern Medical Center that forces cells to rid themselves of mitochondria, researchers are gaining new insights into the function of these critical organelles.

7 Jul 2025

Eating habits directly influence vaginal microbiome, research finds

A cross-sectional study of young Italian women found that higher intake of animal protein and alcohol is associated with vaginal microbiota dysbiosis, while linolenic acid (a plant-based omega-3) and dietary fiber support beneficial Lactobacillus communities.

7 Jul 2025

Study reveals hidden cause of treatment failure in acute promyelocytic leukemia

Researchers at Zhejiang University School of Medicine have identified a single point mutation in the normal PML gene that can block the effect of arsenic trioxide, a frontline drug for acute promyelocytic leukemia.

4 Jul 2025

XPR1 silencing enhances immune response and reduces ovarian tumor growth

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression.

4 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

Chemist awarded NSF grant to study DNA nanoparticles for gene therapy

Case Western Reserve University chemist Divita Mathur was awarded a National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) grant for her research in synthetic DNA nanoparticles, which have potential applications in gene therapy.

4 Jul 2025

Flawed coronavirus model prompts urgent reassessment for drug developers

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections.

4 Jul 2025

Restoring neuron balance in the amygdala reverses anxiety in mice

The Synaptic Physiology laboratory, led by Juan Lerma at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University (UMH) of Elche, has discovered that a specific group of neurons in the amygdala, a brain region involved in emotion regulation, plays a key role in the emergence of conditions such as anxiety, depression, and altered social behavior.

4 Jul 2025

New insights into nature's most remarkable innovation- the ability to sustain a successful pregnancy

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Gene News and Research

Latest Gene News and Research

Aspartame triggers genetic changes tied to glioblastoma severity

Landmark discovery reshapes understanding of key cancer protein MCL-1

New gene editing approach targets mutation behind common genetic heart disease

Developmental timing shapes fluoxetine’s effects on brain energy and mood behavior

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Reversing immune fatigue offers new hope for cancer treatment

Synthetic Biology and the Pursuit of Living Diagnostics and Therapeutics

ADA2 regulates inflammation through lysosomal and extracellular mechanisms

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

Eating habits directly influence vaginal microbiome, research finds

Study reveals hidden cause of treatment failure in acute promyelocytic leukemia

XPR1 silencing enhances immune response and reduces ovarian tumor growth

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

Chemist awarded NSF grant to study DNA nanoparticles for gene therapy

Flawed coronavirus model prompts urgent reassessment for drug developers

Restoring neuron balance in the amygdala reverses anxiety in mice

New insights into nature's most remarkable innovation- the ability to sustain a successful pregnancy

NAD+ supplementation could be a potential treatment for accelerated aging diseases

New study moves closer to defeating dormant tuberculosis cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics