Gene News and Research

Latest Gene News and Research

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Professor Ronald Evans will receive $1.2 million over four years as part of a Network Grant from the Larry L. Hillblom Foundation to examine a molecular pathway that regulates blood sugar and fat independent of insulin.

6 Jan 2022

Comparison of neutralization of SARS-CoV-2 variants of concern Omicron and Delta

The purpose of this study was to determine the breadth of neutralizing activity generated by exposure to certain SARS-CoV-2 variants, vaccinations, or both.

6 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

Cryo-ET reveals molecular mechanisms underlying gene mutations within the eye

For the first time, University of California, Irvine researchers in collaboration with the Max-Planck Institute of Biochemistry, have revealed, at a molecular level, key structural determinants of the highly specialized rod outer segment (ROS) membrane architecture of the eye, which is instrumental to vision.

5 Jan 2022

Scientists discover a division of labor between genetic switches

Two X chromosomes are actually one too many. Female mammalian cells hence switch off one of them – but only when the cells start to specialize into tissues.

5 Jan 2022

Analyzing cell-free RNA could reliably predict preeclampsia

Imaging techniques such as ultrasound technologies and minimally invasive procedures are powerful tools for assessing pregnancy health and progression.

5 Jan 2022

Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

The first comprehensive analysis of viral horizontal gene transfer (HGT) illustrates the extent to which viruses pick up genes from their hosts to hone their infection process, while at the same time hosts also co-opt useful viral genes.

5 Jan 2022

New compound could combat multidrug-resistant pathogens in healthcare settings

For years, public-health experts have been sounding the alarm about the next phase in humanity's co-existence with bacteria - a dark future where emerging strains have rendered once-powerful antibiotics useless.

5 Jan 2022

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

5 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

The Wistar Institute announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

5 Jan 2022

Hospitalization and death associated with SARS-CoV-2 Omicron variant compared to Delta variant

Researchers evaluate the rates of hospitalization and deaths associated with the SARS-CoV-2 Omicron variant as compared to the Delta variant.

5 Jan 2022

Nucleocapsid protein preferentially binds to structured and longer RNA to deliver viral proteins in host circulation

Results from a new study could be crucial in studying the molecular and biochemical basis of SARS-CoV-2 infection at a more granular level and help in strategizing therapeutic solutions to treat and manage COVID-19 effectively.

5 Jan 2022

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

A new preprint research paper posted to the medRxiv* server reports the induction of high neutralizing activity in these patients against the Omicron VOC with a booster dose.

5 Jan 2022

New gene therapy addresses primary cellular deficit associated with limb-girdle muscular dystrophy 2B

Children's National Hospital experts developed a new pre-clinical gene therapy for a rare disorder, known as limb-girdle muscular dystrophy (LGMD) 2B, that addresses the primary cellular deficit associated with this disease.

4 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

Novel insight into the immune characteristics of bats

Many studies have indicated that bats are significant reservoirs of innumerable viruses, such as influenza, coronaviruses, and rabies. These studies have also reported that bats predominantly remain asymptomatic or develop mild diseases during viral infections caused by henipaviruses, Ebola virus, coronaviruses, etc.

4 Jan 2022

Research provides compelling insights into the complex nature of genomic imprinting in mice

Mammalian offspring inherit two versions, or alleles, of each gene with one allele from each biological parent. However, gene expression is tightly regulated and certain genes undergo the phenomenon of "genomic imprinting", which is where only the allele received by the male or the female parent is expressed.

4 Jan 2022

New insights into how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Very high rates of asymptomatic infection with Omicron compared to prior SARS-CoV-2 variants

The advent of the B.1.1.529 (Omicron) severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) variant, detected initially in Botswana and South Africa and now found in over 135 countries as of January 3, 2022, has sparked fears of a new global wave of infections and hospitalizations

3 Jan 2022

Gene News and Research

Latest Gene News and Research

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Comparison of neutralization of SARS-CoV-2 variants of concern Omicron and Delta

SARS-CoV-2 appears to persist in organs throughout the body for months

Cryo-ET reveals molecular mechanisms underlying gene mutations within the eye

Scientists discover a division of labor between genetic switches

Analyzing cell-free RNA could reliably predict preeclampsia

Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

New compound could combat multidrug-resistant pathogens in healthcare settings

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

Hospitalization and death associated with SARS-CoV-2 Omicron variant compared to Delta variant

Nucleocapsid protein preferentially binds to structured and longer RNA to deliver viral proteins in host circulation

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

New gene therapy addresses primary cellular deficit associated with limb-girdle muscular dystrophy 2B

Unique nanoparticle can deliver genome editing technology to endothelial cells

Novel insight into the immune characteristics of bats

Research provides compelling insights into the complex nature of genomic imprinting in mice

New insights into how tiny bacteria from the environment have adapted to live inside humans

Very high rates of asymptomatic infection with Omicron compared to prior SARS-CoV-2 variants

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting