Gene News and Research

Latest Gene News and Research

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome.

2 Jul 2021

Researchers highlight easily adoptable methods to improve outcomes for patients with gastroesophageal cancer

Two Roswell Park Comprehensive Cancer Center experts were invited to present new insights on treatment of gastroesophageal cancers during the European Society for Medical Oncology World Congress on Gastrointestinal Cancer 2021.

2 Jul 2021

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress.

2 Jul 2021

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

In cancer research, it's a common goal to find something about cancer cells -- some sort of molecule -- that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. Even better: The molecule isn't present in healthy cells, so they remain untouched by the new therapy.

2 Jul 2021

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

A year after University at Buffalo scientists demonstrated that it was possible to produce millions of mature human cells in a mouse embryo, they have published a detailed description of the method so that other laboratories can do it, too.

2 Jul 2021

Salivary markers of oxidative stress during severe COVID-19

An interesting study from researchers at the University of Sharjah, Sharjah, United Arab Emirates, presents evidence that an elevated level of expression of oxidant molecules may be correlated with severe infection and lung injury.

2 Jul 2021

New study to test the scalability of offering preventive DNA screening to young adults for cancer risk

A landmark new DNA screening study to identify cancer risk in young adults will go ahead, after Monash University researcher Associate Professor Paul Lacaze was awarded a $2.97 million Medical Research Future Fund (MRFF) grant today.

2 Jul 2021

Tell-tale signs of high stroke risk may appear a decade in advance

The tell-tale signs of a person’s susceptibility to a stroke may appear up to 10 years before the event, suggests research published online in the Journal of Neurology Neurosurgery & Psychiatry.

2 Jul 2021

Genetic variants in a neuro-associated gene cause neurodevelopmental disorder, finds study

Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect how the brain functions.

2 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Researchers in Italy have shown that leaf extract from the common grapevine – Vitis vinifera – exhibits significant antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

1 Jul 2021

Researchers evaluate tools for identification of microRNAs in plants

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

1 Jul 2021

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.

1 Jul 2021

Study offers clues for earlier diagnosis of folate deficiency

As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who carry certain genetic variants, dealing with folate deficiency can be a life-long struggle which can lead to serious neurological and heart problems and even death.

1 Jul 2021

Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

Lowering levels of a hormone called PTHrP can prevent metastases and improve survival in mice with pancreatic cancer and could lead to a new way to treat patients, according to a study from cancer researchers at Columbia University Vagelos College of Physicians and Surgeons and Herbert Irving Comprehensive Cancer Center and with collaborators at the University of Pennsylvania.

1 Jul 2021

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, and Nippon Gene Co., Ltd (Nippon Gene), a manufacturer of genetic engineering research reagents and diagnostic reagents for humans, animals, and plants, today announced a non-exclusive license agreement granting Nippon Gene access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

1 Jul 2021

New software tool can help identify gene regulators more efficiently

A team of scientists at the University of Illinois Chicago has developed a software tool that can help researchers more efficiently identify the regulators of genes. The system leverages a machine learning algorithm to predict which transcription factors are most likely to be active in individual cells.

1 Jul 2021

Cancer cells become more aggressive when exposed to tissue stiffening

In cases of breast cancer, bone metastasis - when cancer cells spread to new sites in the bone - causes the most breast cancer-related harm and is often incurable in advanced disease. A new study by University of Arizona Health Sciences researchers found that cancer cells become more aggressive when exposed to tissue stiffening and that these changes persist over time.

1 Jul 2021

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

Researchers from collaborating universities in Virginia have recently utilized transgenic mice to explore the effects of SARS-CoV-2 on associated lung injury.

30 Jun 2021

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis.

30 Jun 2021

Gene News and Research

Latest Gene News and Research

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Researchers highlight easily adoptable methods to improve outcomes for patients with gastroesophageal cancer

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

Salivary markers of oxidative stress during severe COVID-19

New study to test the scalability of offering preventive DNA screening to young adults for cancer risk

Tell-tale signs of high stroke risk may appear a decade in advance

Genetic variants in a neuro-associated gene cause neurodevelopmental disorder, finds study

Is there a link between circadian rhythms and COVID-19 severity?

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Researchers evaluate tools for identification of microRNAs in plants

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Study offers clues for earlier diagnosis of folate deficiency

Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

New software tool can help identify gene regulators more efficiently

Cancer cells become more aggressive when exposed to tissue stiffening

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)