Gene News and Research

Latest Gene News and Research

Researchers identify a novel vulnerability in advanced prostate cancer

Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy.

3 Nov 2020

Blood vessel malformations originate in vein cells

In the condition known as cavernoma, lesions arise in a cluster of blood vessels in the brain, spinal cord or retina. Researchers from Uppsala University can now show, at molecular level, that these changes originate in vein cells.

3 Nov 2020

Study: 1 in 8 patients with cancer have inherited gene mutations

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine.

2 Nov 2020

Two studies find age as a primary factor in melanoma treatment resistance

Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.

2 Nov 2020

Study analyzes the viral load on Halloween candy handled by COVID-19 patients

Like a specter, the question looms: How risky is trick-or-treating with SARS-Cov-2, the virus that causes COVID-19, in the air -- and possibly on the candy?

30 Oct 2020

Researchers identify distinct link between autism and brain cell abnormalities

Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.

30 Oct 2020

"Training" the immune system with β-glucan compound may improve immune recovery

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer.Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Research projects receive BTCA grants to develop novel drugs for various diseases

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

30 Oct 2020

Time machine suggests a drug testing approach for pancreatic cancer

Many patients with pancreatic cancer have only about a 10% chance of survival within five years of their diagnosis because they tend to become resistant to chemotherapy, past studies have indicated.

30 Oct 2020

Scientists use new approach to analyze millions of chemical-gene interactions

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

A2B-COVID: Rapid identification of SARS-CoV-2 transmission

A new study published on the preprint server medRxiv in October 2020 reports a method to assess transmission potential for any event in the current pandemic, using what is known about the virus's spread, data on the mobility of individuals, and new ways of processing genomic sequencing data. The outcome is to determine whether cases are linked or not so as to take action to prevent further spread.

29 Oct 2020

SARS-CoV-2 load varies widely in the community and over time

A new study published on the preprint server medRxiv* in October 2020 reports that there are large differences in the viral load in different communities. Moreover, the authors say that the cycle threshold values required to obtain a positive result for viral RNA by polymerase chain reaction may provide an early warning of an outbreak.

29 Oct 2020

UH and CWRU announce Phase 3 trial of Astrazeneca's investigational COVID-19 vaccine

University Hospitals and Case Western Reserve University announced today that UH Cleveland Medical Center has been selected as a clinical trial site for the Phase 3 global study of an investigational vaccine against SARS-CoV-2, sponsored by AstraZeneca.

29 Oct 2020

Toxin-carrying virus implicated in the emergence of new Salmonella strain in pigs

Researchers at the Quadram Institute have implicated a toxin-carrying virus in the emergence of a new strain of Salmonella in pigs.

29 Oct 2020

Study reveals how gene control mechanisms define the identity of developing brainstem neurons

A recent study at the University of Helsinki reveals how gene control mechanisms define the identity of developing neurons in the brainstem.

29 Oct 2020

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.

29 Oct 2020

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan.

29 Oct 2020

Antiviral inhibitor DDX42 shows broad activity against Chikungunya, HIV and SARS-CoV-2

By exploiting type 1 interferon's ability to foster an antagonistic cellular environment for viral replication, a research group from France pinpointed DEAD-box RNA helicase DDX42 as an intrinsic inhibitor of HIV, but also other pathogenic viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Chikungunya virus.

29 Oct 2020

Tumor suppressor gene represses 'jumping genes'

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or "jumping genes," from hopping around the human genome.

29 Oct 2020

Study sheds new light on cell division fidelity, can impact future regenerative medicine

Researchers discover that a specialized part of the chromosomes, essential for a correct cell division, is smaller and weaker in stem cells, when compared to the ones of differentiated cells.

29 Oct 2020

Gene News and Research

Latest Gene News and Research

Researchers identify a novel vulnerability in advanced prostate cancer

Blood vessel malformations originate in vein cells

Study: 1 in 8 patients with cancer have inherited gene mutations

Two studies find age as a primary factor in melanoma treatment resistance

Study analyzes the viral load on Halloween candy handled by COVID-19 patients

Researchers identify distinct link between autism and brain cell abnormalities

"Training" the immune system with β-glucan compound may improve immune recovery

Research projects receive BTCA grants to develop novel drugs for various diseases

Time machine suggests a drug testing approach for pancreatic cancer

Scientists use new approach to analyze millions of chemical-gene interactions

A2B-COVID: Rapid identification of SARS-CoV-2 transmission

SARS-CoV-2 load varies widely in the community and over time

UH and CWRU announce Phase 3 trial of Astrazeneca's investigational COVID-19 vaccine

Toxin-carrying virus implicated in the emergence of new Salmonella strain in pigs

Study reveals how gene control mechanisms define the identity of developing brainstem neurons

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Antiviral inhibitor DDX42 shows broad activity against Chikungunya, HIV and SARS-CoV-2

Tumor suppressor gene represses 'jumping genes'

Study sheds new light on cell division fidelity, can impact future regenerative medicine

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