Gene News and Research

Latest Gene News and Research

Cell biologists and bioimaging expert team up to solve fourth dimension secrets

Cell biologists at the University of Illinois at Urbana-Champaign and Bar-Ilan University at Israel and a bioimaging expert at the University of Central Florida are teaming up in what they hope may lead to a major breakthrough in understanding of the three-dimensional organization of the nucleus over time and their role in certain diseases.

29 Oct 2020

Study reveals complex and vast diversity of African genetic variation

The study, in which six Wits researchers were involved, show that these newly discovered variants were found mostly among newly sampled ethnolinguistic groups.

29 Oct 2020

Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

A key hurdle in treating breast cancers is intratumoral heterogeneity, or the presence of multiple different cell populations within the same tumor that have distinct characteristics such as gene expression, metabolism and ability to divide, spread and grow.

29 Oct 2020

Mouth may be primary route of SARS-CoV-2 infection and transmission

A new study published on the preprint server medRxiv in October 2020 shows that the virus also multiplies robustly in the oral cavity, indicating that saliva plays a role in viral transmission.

29 Oct 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

Genome-wide CRISPR screens reveal resistance and sensitization mechanisms of drugs used in COVID-19

By leveraging nucleotide triphosphate analog-induced cell death, Chinese researchers unveiled genes that affect the import, export, and metabolism of pervasively used antiviral drugs in the treatment of coronavirus disease (COVID-19). This exciting study is currently available on the bioRxiv* preprint server.

28 Oct 2020

Cognitive disorders associated with risk for developing severe COVID-19

Dementia and other cognitive disorders now appear to be risk factors for developing severe COVID-19, according to research from the University of Georgia. The findings highlight the need for special care for populations with these preexisting conditions during the pandemic.

28 Oct 2020

Penn researchers awarded $5.4 million to find genetic risk markers for testicular cancer

The international hunt to find more genetic risk markers for testicular cancer is expanding. A team of researchers led by Katherine L. Nathanson, MD, deputy director of the Abramson Cancer Center and the Pearl Basser Professor for BRCA-Related Research in the Perelman School of Medicine at the University of Pennsylvania, was recently awarded $5.4 million over five years from the National Institutes of Health to continue the long-standing genomics work of the TEsticular CAncer Consortium (TECAC).

28 Oct 2020

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Genetic factors that reduce the placenta's capacity to protect the fetus from the zika virus are described by Brazilian researchers in an article published in PLOS Neglected Tropical Diseases.

28 Oct 2020

Scientists use experimental approach to identify genes and interactions

A phage is a virus that invades a bacterial cell. While harmless to human cells, phages are potentially deadly to bacteria since many phages enter a cell in order to hijack its machinery in order to reproduce itself, thus destroying the cell.

28 Oct 2020

Researchers demonstrate potent antibody that fights against coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Genetic analysis with RNA sequencing can increase diagnostic yield, shows study

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

28 Oct 2020

Researchers identify physiological mechanism that maintains regenerative capacity of muscle stem cells

Researchers at UPF, the National Centre for Cardiovascular Research, ICREA and Ciberned have identified a physiological mechanism that maintains the regenerative capacity of muscle stem cells, and surprisingly resists the passage of time far more than expected, until geriatric age.

28 Oct 2020

Specific genes of infant gut bacterium determine its symbiotic function in the infant's gut

While an infant's genes distinguish her from other newborns, a new peer-reviewed study reports that specific genes of a particular infant gut bacterium determine its symbiotic function in the infant's gut.

28 Oct 2020

Gut's immune response to SARS-CoV-2 very different from the lung

Megan L. Stanifer et al. study the immune response in the human gut upon SARS-CoV-2 infection. The study published as a bioRxiv* preprint reveals a robust proinflammatory response: a cell type-specific or a tissue-specific regulation of interferon-mediated signaling during SARS-CoV-2 infection.

27 Oct 2020

WSU research sheds new light on a drug that may be used to treat hypertrophic cardiomyopathy

Research at Washington State University sheds new light on one molecule that may be used to treat a heart condition that can lead to stroke, heart attack and other forms of heart disease.

27 Oct 2020

Inflammasome may play a key role in triggering immune response to cancer

The inflammasome — a protein signaling network that is activated to rid the body of virus or bacteria-infected cells — may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers.

27 Oct 2020

Scientists uncover surprising players in acute liver failure

Acute liver failure is a devastating, rapidly progressing disease that results in death in 80% of cases, unless an emergency liver transplant is performed. In the developed world, its leading cause is a substantial overdose of acetaminophen, also known as paracetamol.

27 Oct 2020

Study shows how a genetic mutation causes common sleep syndrome

A new study by researchers at UC Santa Cruz shows how a genetic mutation throws off the timing of the biological clock, causing a common sleep syndrome called delayed sleep phase disorder.

27 Oct 2020

Proton regulator of essential cancer miRNA discovered

MicroRNAs (miRNAs) are evolutionarily conserved small noncoding RNAs - bits of genetic code that serve as critical gene regulators in many aspects of biological processes important for human health.

27 Oct 2020

Gene News and Research

Latest Gene News and Research

Cell biologists and bioimaging expert team up to solve fourth dimension secrets

Study reveals complex and vast diversity of African genetic variation

Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

Mouth may be primary route of SARS-CoV-2 infection and transmission

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Genome-wide CRISPR screens reveal resistance and sensitization mechanisms of drugs used in COVID-19

Cognitive disorders associated with risk for developing severe COVID-19

Penn researchers awarded $5.4 million to find genetic risk markers for testicular cancer

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Scientists use experimental approach to identify genes and interactions

Researchers demonstrate potent antibody that fights against coronavirus

Genetic analysis with RNA sequencing can increase diagnostic yield, shows study

Researchers identify physiological mechanism that maintains regenerative capacity of muscle stem cells

Specific genes of infant gut bacterium determine its symbiotic function in the infant's gut

Gut's immune response to SARS-CoV-2 very different from the lung

WSU research sheds new light on a drug that may be used to treat hypertrophic cardiomyopathy

Inflammasome may play a key role in triggering immune response to cancer

Scientists uncover surprising players in acute liver failure

Study shows how a genetic mutation causes common sleep syndrome

Proton regulator of essential cancer miRNA discovered

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)