Gene News and Research

Latest Gene News and Research

Humans are not the first to exploit benefits of CRISPR technique, research shows

In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have learned how to harness these clever natural systems in the biotech and pharmaceutical industries, among other areas.

24 Mar 2020

Research reveals important mechanism in the repair of DNA double-strand breaks

Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife.

24 Mar 2020

Researchers rejuvenate aged human cells with stem cell technology

Scientists have used stem cell technology to force old human cells to rejuvenate, reversing the impact that aging has on cells.

24 Mar 2020

Old human cells regain youthful strength after rejuvenating protein treatment, study finds

Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development, according to a new study by researchers at the Stanford University School of Medicine.

24 Mar 2020

ELS can be useful in measuring outcomes for treatment studies in intellectual disabilities

A multi-university team of researchers found that expressive language sampling can be useful in measuring outcomes in clinical trials targeting fragile X syndrome.

24 Mar 2020

Celltrion announces key milestones in its efforts to fight COVID-19

Celltrion Group today announced key milestones in its efforts to fight the 2019 novel coronavirus (COVID-19) pandemic.

23 Mar 2020

UNC researchers look to NGS for better understanding of COVID-19

It might be the future of diagnostic testing for common infections, and could prove to be a crucial tool for understanding and fighting novel viruses.

23 Mar 2020

OncoMX knowledgebase improves exploration of cancer biomarkers and related evidence

The OncoMX knowledgebase will improve the exploration and research of cancer biomarkers in the context of related evidence, according to a recent article from the George Washington University.

23 Mar 2020

3D chromatin landscapes in T cell acute lymphoblastic leukemia important beyond DNA code changes

Children with aggressive blood cancers have differences -- not just in the DNA code of their blood cells -- but also in the heavily twisted protein superstructure that controls access to genes.

23 Mar 2020

Fatty acid-binding protein 4 plays an important role in kidney stone formation

Kidney stone disease has a high prevalence worldwide, ranging up to 13% in North America, 9% in Europe, and 5% in Asia. They are painful for patients, often lead to surgery, and impart a significant economic impact.

23 Mar 2020

CAR macrophages can be used to effectively fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors.

23 Mar 2020

Neurotensinergic neurons in the brainstem regulate non-REM sleep

Mammals experience rapid eye movement and non-REM sleep. While the hypothalamus and brainstem are known to be a critical regulators of sleep, the precise mechanism is not fully understood.

23 Mar 2020

Melinjo seed extract may improve obesity and diabetes

In Southeast Asia, the fruit, flowers, and leaves of Indonesia's "Melinjo" tree are traditional foods.

23 Mar 2020

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

A study found that children with aggressive blood cancers have different superstructures of the proteins that control gene access.

23 Mar 2020

A review of the literature on acute promyelocytic leukemia

Oncotarget Volume 11, Issue 11 reported that relapsed APL, particularly in the high-risk subset of patients, remains an important clinical problem.

22 Mar 2020

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Oncotarget Volume 11, Issue 11 reported that in order to understand the molecular mechanism of the dependency in MM, the research team examined gene expression changes upon DOT1L inhibition in sensitive and insensitive cell lines and discovered that genes belonging to the endoplasmic reticulum stress pathway and protein synthesis machinery were specifically suppressed in sensitive cells.

22 Mar 2020

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

MingKuan Lin, Research Assistant Professor, INOVA Neuroscience, School of Systems Biology, is working to measure gene expression levels in blood from patients undergoing treatment with buprenorphine for opioid use disorder.

22 Mar 2020

Study uncovers a new childhood-onset neurodegenerative disorder

A study has uncovered a new neurodegenerative disorder in which children experience developmental regression and severe epilepsy.

21 Mar 2020

DSI alumni use computational design to quickly discover treatments for COVID-19

Two graduates of the Data Science Institute at Columbia University are using computational design to quickly discover treatments for the coronavirus.

21 Mar 2020

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

Researchers at the Centro Nacional de Investigaciones Cardiovasculares, working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cells, the cells that line the interior of blood vessels.

21 Mar 2020

Gene News and Research

Latest Gene News and Research

Humans are not the first to exploit benefits of CRISPR technique, research shows

Research reveals important mechanism in the repair of DNA double-strand breaks

Researchers rejuvenate aged human cells with stem cell technology

Old human cells regain youthful strength after rejuvenating protein treatment, study finds

ELS can be useful in measuring outcomes for treatment studies in intellectual disabilities

Celltrion announces key milestones in its efforts to fight COVID-19

UNC researchers look to NGS for better understanding of COVID-19

OncoMX knowledgebase improves exploration of cancer biomarkers and related evidence

3D chromatin landscapes in T cell acute lymphoblastic leukemia important beyond DNA code changes

Fatty acid-binding protein 4 plays an important role in kidney stone formation

CAR macrophages can be used to effectively fight solid tumors

Neurotensinergic neurons in the brainstem regulate non-REM sleep

Melinjo seed extract may improve obesity and diabetes

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

A review of the literature on acute promyelocytic leukemia

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

Study uncovers a new childhood-onset neurodegenerative disorder

DSI alumni use computational design to quickly discover treatments for COVID-19

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research