Gene News and Research

Latest Gene News and Research

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal.

30 Sep 2019

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications.

30 Sep 2019

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles, according to work from a team of current and former Carnegie biologists led by Chen-Ming Fan and published in Nature Metabolism.

30 Sep 2019

Triplet therapy could benefit patients with BRAF-mutant metastatic colorectal cancer

Results presented today at the ESMO Congress 2019, Barcelona 27 September - 01 October, during the second Proffered Paper Session on Gastrointestinal tumors (colorectal) by VHIO's Director, Josep Tabernero, show that the triplet combination of the BRAF inhibitor, encorafenib, MEK inhibitor, binimetinib, and EGFR inhibitor, cetuximab, not only significantly improves overall survival but also increases objective response rates compared with standard of care in patients with BRAF V600E-mutant metastatic colorectal cancer.

30 Sep 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

Johns Hopkins researchers develop new way to deliver sight-saving gene therapy to the retina

In experiments with rats, pigs and monkeys, Johns Hopkins Medicine researchers have developed a way to deliver sight-saving gene therapy to the retina.

From Johns Hopkins Medicine 30 Sep 2019

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

Researchers at Queen Mary University of London and University College London have shown that using stem cells derived from patients could help find new treatments for a group of congenital muscular dystrophies.

30 Sep 2019

New method can help detect melanoma cells in skin tumors

Melanoma is the least common but one of the most deadly skin cancers. It accounts for only about one percent of all cases globally, but the majority of skin cancer deaths.

30 Sep 2019

Novel therapeutic approach improves survival in patients newly diagnosed with advanced ovarian cancer

An international study demonstrates that administering niraparib after conventional chemotherapy treatment in patients newly diagnosed with advanced ovarian cancer, improves their progression-free survival, and reduces their risk of relapse or death from this disease.

28 Sep 2019

Lifelong choline supplementation holds potential to prevent Alzheimer's disease

In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease.

27 Sep 2019

Human aging processes may hinder cancer development, study finds

A new study, published in Aging Cell, has found that human aging processes may hinder cancer development.

27 Sep 2019

Researchers identify genetic variants related to starting point of Parkinson's disease

Researchers from the Institute of Neurosciences of the University of Barcelona, Hospital Clínic and the August Pi i Sunyer Biomedical Research Institute have identified a group of genetic variants related to the starting point of Parkinson's disease.

27 Sep 2019

Functional three-organoid stem cell system could lead to unprecedented advances for precision medicine

Using iPS cells, a Japanese research group has successfully grown a connected set of organs at the same time, including a liver and a pancreas connected by a bile duct.

27 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Exposure to air pollution during pregnancy associated with reductions in children's lung function

New research by the Centre for Environmental Health and Sustainability (CESH) at the University of Leicester indicates that exposure to air pollution from road traffic as early as the first trimester of pregnancy and in early life is associated with small but significant reductions in children's lung function at the age of eight years.

27 Sep 2019

Study provides new insights on how influenza virus achieves efficient viral RNA replication

New insights on how subunits of the influenza virus polymerase co-evolve to ensure efficient viral RNA replication are provided by a study published October 3 in the open-access journal PLOS Pathogens by Nadia Naffakh of the Institut Pasteur, and colleagues. As the authors note, the findings could lead to novel strategies for antiviral drug development.

From PLOS ONE 27 Sep 2019

Gene News and Research

Latest Gene News and Research

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

Triplet therapy could benefit patients with BRAF-mutant metastatic colorectal cancer

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

Johns Hopkins researchers develop new way to deliver sight-saving gene therapy to the retina

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

New method can help detect melanoma cells in skin tumors

Novel therapeutic approach improves survival in patients newly diagnosed with advanced ovarian cancer

Lifelong choline supplementation holds potential to prevent Alzheimer's disease

Human aging processes may hinder cancer development, study finds

Researchers identify genetic variants related to starting point of Parkinson's disease

Functional three-organoid stem cell system could lead to unprecedented advances for precision medicine

Scientists use ultrasound to detect active genes in live cells

Exposure to air pollution during pregnancy associated with reductions in children's lung function

Study provides new insights on how influenza virus achieves efficient viral RNA replication

Biological clock responds positively to stress

Study may help scientists to learn more about the causes of chronic pain

New study on gene modulation may help prevent blindness

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging