Gene News and Research

Latest Gene News and Research

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled trial of the drug, which is being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).

31 Mar 2020

New blood test accurately detects more than 50 types of cancer

Researchers have developed a blood test that could accurately detect up to 50 types of cancers, and some of these detections could be even before the symptoms appear. The test would help physicians detect the origin or the source of cancer within the body explain the researchers from the European Society of Oncology. The study titled, "Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA," was published in the latest issue of the journal Annals of Oncology.

30 Mar 2020

New microfluidic chip can mimic hypoxic conditions after a heart attack

Researchers led by biomedical engineers at Tufts University invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack - specifically when an artery is blocked in the heart and then unblocked after treatment.

30 Mar 2020

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Paternal alcohol consumption before conception could affect child development

Scientists at the University of California, Riverside, have explored the relationship between parental alcohol consumption -- before conception in the case of fathers and during pregnancy in the case of mothers -- and offspring development.

30 Mar 2020

Zebrafish can provide genetic clues to human nicotine addiction

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic clues to smoking, a complex human behavior.

30 Mar 2020

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year.

30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

New method to treat blindness using retinal cell production

Scientists in Sweden have innovated a method of treating blindness using embryonic stem cells to produce retinal cells.

30 Mar 2020

Researchers discover new way to refine production of retinal cells to treat blindness

Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly.

30 Mar 2020

Gene that could affect the progress of ALS discovered

Researchers from the Zuckerman Institute at Columbia University have successfully found a gene that could work towards accelerating the progression of ALS or amyotrophic lateral sclerosis. The study titled, "The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice," was published in the latest issue of the journal Neuron.

29 Mar 2020

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio.

27 Mar 2020

Genetic mutation found to improve cognitive flexibility in mice

Researchers at the National Institutes of Health have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility--the ability to adapt to changing situations.

27 Mar 2020

Researchers examining gene coexpression and brain connectivity in females with ASD

Allison Jack, Assistant Professor, Psychology, is examining gene coexpression and brain connectivity in females with autism spectrum disorder.

27 Mar 2020

Study shows how copper boosts pig growth

Pigs have better feed conversion rates with copper in their diets, but until now, scientists didn't fully understand why.

27 Mar 2020

Scientists discover a completely new antibiotic resistance gene

Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria.

27 Mar 2020

Gene therapy investigators can greatly benefit from National Gene Vector Biorepository

Gene therapy investigators can greatly benefit from the resources and services provided by the National Gene Vector Biorepository, housed at the Indiana University School of Medicine.

27 Mar 2020

Maintaining VDR levels in pancreatic cells could protect against diabetes

Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of the disease.

27 Mar 2020

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Oncotarget Volume 11, Issue 12 reported that using the HL-60 human non-APL AML model where ATRA causes nuclear enrichment of c-Raf that drives differentiation/G0-arrest, the research team now observe that roscovitine enhanced nuclear enrichment of certain traditionally cytoplasmic signaling molecules and enhanced differentiation and cell cycle arrest.

26 Mar 2020

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW-Madison study shows.

26 Mar 2020

Gene News and Research

Latest Gene News and Research

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

New blood test accurately detects more than 50 types of cancer

New microfluidic chip can mimic hypoxic conditions after a heart attack

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

Paternal alcohol consumption before conception could affect child development

Zebrafish can provide genetic clues to human nicotine addiction

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Research could open up new therapeutic strategies for some lung and kidney cancers

New method to treat blindness using retinal cell production

Researchers discover new way to refine production of retinal cells to treat blindness

Gene that could affect the progress of ALS discovered

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Genetic mutation found to improve cognitive flexibility in mice

Researchers examining gene coexpression and brain connectivity in females with ASD

Study shows how copper boosts pig growth

Scientists discover a completely new antibiotic resistance gene

Gene therapy investigators can greatly benefit from National Gene Vector Biorepository

Maintaining VDR levels in pancreatic cells could protect against diabetes

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)