Gene News and Research

Latest Gene News and Research

New gene therapy improves vision in blind mice

Mice born blind have shown significant improvement in vision after undergoing a new gene therapy developed by a team of Japanese scientists.

7 Feb 2020

Research provides new insights into molecular basis of X-chromosome inactivation

Researchers at the European Molecular Biology Laboratory in Heidelberg and Institut Curie in Paris have shown that the protein SPEN plays a crucial role in the process of X-chromosome inactivation, whereby female mammalian embryos silence gene expression on one of their two X chromosomes.

7 Feb 2020

Gene therapy approach could pave the way for treatment of Stargardt disease

A leading Professor of Ophthalmology at the University of Oxford has shared the details of his research which could pave the way for a new treatment for sight loss condition Stargardt disease.

7 Feb 2020

Rejuvenate Bio secures license to commercialize gene therapy for treating age-related diseases in dogs

Rejuvenate Bio has secured a license to commercialize a gene therapy technology developed at the Wyss Institute to treat multiple age-related diseases in dogs, which could open the door to similar treatments for humans in the future.

6 Feb 2020

Coronavirus - pandemic or not?

The coronavirus strain called 2019-nCoV has been causing widespread illness in China, with 28,276 affected by the virus and over 565 deaths worldwide, mostly in China. As of now, it is already more deadly than the SARS epidemic that raged between 2002 and 2004.

6 Feb 2020

Largest genome study sheds light on how genetic glitches trigger tumor formation

It is well-known that when a gene mutates, it triggers tumor formation by stimulating abnormal cell growth and proliferation. Cancer starts from a mutant gene that kickstarts a series of abnormal growth, forming a tumor. However, the exact mechanism of how this happens remains unclear.

6 Feb 2020

Researchers discover new mutational phenomenon chromothripsis in cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.

6 Feb 2020

New insight into genomic alterations associated with telomere maintenance mechanisms in cancer

To gain an infinite lifespan, cancer cells need to maintain the ends of their chromosomes, known as telomeres. They achieve this in various different ways.

6 Feb 2020

Analyzing cancer-specific alterations found in tumor's RNA

Researchers at EMBL-EBI were among the leaders of a large international consortium that carried out a joint analysis of data from over 1000 donors of more than 25 cancer types, studying data on their whole genomes along with tumor transcriptome data, which indicates the genes that are active within a tumor.

6 Feb 2020

Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

Dementia is one of the most debilitating consequences of Parkinson's disease, a progressive neurological condition characterized by tremors, stiffness, slow movement and impaired balance.

6 Feb 2020

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

Breastfeeding women with a pathogenic BRCA1 or BRCA2 genetic mutation face a significant risk, even at a young age, of breast and ovarian cancer.

6 Feb 2020

Researchers discover new genetic drivers of cancer

The discovery of genetic drivers of cancer can have critical implications for the diagnosis and treatment of cancer patients, yet genome analysis has focused primarily on only 1-2% of the whole genome - the part that contains the code for making proteins.

5 Feb 2020

Gut bacteria help regulate contraction and relaxation of colon muscles

Micro-organisms in the gut support healthy digestion by helping nerve cells within the intestine to regulate the contraction and relaxation of the muscle wall of the colon, according to new research from the Crick and Bern University.

5 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Analysis shows overall survival in lung cancer patients harboring 'niche' mutations

Mutations were observed in all genes studied, except c-MET, DDR2, MAP2K1, and RET.

5 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020

Prenatal single cell blood test for gene defects

With the current state of knowledge regarding genetic testing, non-invasive prenatal testing (NIPT) is in favor for genetic testing in unborn babies, using fragments of DNA circulating in the mother’s blood.

4 Feb 2020

Study uncovers more pieces of the autism puzzle

A major international study from the Autism Sequencing Consortium with participation of researchers from the Danish iPSYCH psychiatry project, has recently mapped 102 new autism genes.

4 Feb 2020

RNA affecting skin cancer progression discovered

Researchers at the University of Turku, Turku University Central Hospital, and Western Cancer Center have discovered a new RNA molecule, PRECSIT, which regulates the growth and invasion of squamous cell carcinoma of the skin.

4 Feb 2020

Developing tests for genetic signs could lead to earlier cancer detection

Early signs of cancer can appear years before diagnosis and developing tests for these genetic signs could provide new ways to spot cancer early, according to new research led by the Crick and EMBL-EBI, and supported by an international cancer genomics consortium, the Pan-Cancer Analysis of Whole Genomes Project.

4 Feb 2020

Gene News and Research

Latest Gene News and Research

New gene therapy improves vision in blind mice

Research provides new insights into molecular basis of X-chromosome inactivation

Gene therapy approach could pave the way for treatment of Stargardt disease

Rejuvenate Bio secures license to commercialize gene therapy for treating age-related diseases in dogs

Coronavirus - pandemic or not?

Largest genome study sheds light on how genetic glitches trigger tumor formation

Researchers discover new mutational phenomenon chromothripsis in cancer

New insight into genomic alterations associated with telomere maintenance mechanisms in cancer

Analyzing cancer-specific alterations found in tumor's RNA

Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

Researchers discover new genetic drivers of cancer

Gut bacteria help regulate contraction and relaxation of colon muscles

Study may suggest new therapeutic approaches to control immune responses

Analysis shows overall survival in lung cancer patients harboring 'niche' mutations

Making it all work: brain-dependent immune activation in embryos

Prenatal single cell blood test for gene defects

Study uncovers more pieces of the autism puzzle

RNA affecting skin cancer progression discovered

Developing tests for genetic signs could lead to earlier cancer detection

Genomics - Industry Focus eBook (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research