Gene News and Research

Latest Gene News and Research

Celltrion announces key milestones in its efforts to fight COVID-19

Celltrion Group today announced key milestones in its efforts to fight the 2019 novel coronavirus (COVID-19) pandemic.

23 Mar 2020

UNC researchers look to NGS for better understanding of COVID-19

It might be the future of diagnostic testing for common infections, and could prove to be a crucial tool for understanding and fighting novel viruses.

23 Mar 2020

OncoMX knowledgebase improves exploration of cancer biomarkers and related evidence

The OncoMX knowledgebase will improve the exploration and research of cancer biomarkers in the context of related evidence, according to a recent article from the George Washington University.

23 Mar 2020

3D chromatin landscapes in T cell acute lymphoblastic leukemia important beyond DNA code changes

Children with aggressive blood cancers have differences -- not just in the DNA code of their blood cells -- but also in the heavily twisted protein superstructure that controls access to genes.

23 Mar 2020

Fatty acid-binding protein 4 plays an important role in kidney stone formation

Kidney stone disease has a high prevalence worldwide, ranging up to 13% in North America, 9% in Europe, and 5% in Asia. They are painful for patients, often lead to surgery, and impart a significant economic impact.

23 Mar 2020

CAR macrophages can be used to effectively fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors.

23 Mar 2020

Neurotensinergic neurons in the brainstem regulate non-REM sleep

Mammals experience rapid eye movement and non-REM sleep. While the hypothalamus and brainstem are known to be a critical regulators of sleep, the precise mechanism is not fully understood.

23 Mar 2020

Melinjo seed extract may improve obesity and diabetes

In Southeast Asia, the fruit, flowers, and leaves of Indonesia's "Melinjo" tree are traditional foods.

23 Mar 2020

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

A study found that children with aggressive blood cancers have different superstructures of the proteins that control gene access.

23 Mar 2020

A review of the literature on acute promyelocytic leukemia

Oncotarget Volume 11, Issue 11 reported that relapsed APL, particularly in the high-risk subset of patients, remains an important clinical problem.

22 Mar 2020

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Oncotarget Volume 11, Issue 11 reported that in order to understand the molecular mechanism of the dependency in MM, the research team examined gene expression changes upon DOT1L inhibition in sensitive and insensitive cell lines and discovered that genes belonging to the endoplasmic reticulum stress pathway and protein synthesis machinery were specifically suppressed in sensitive cells.

22 Mar 2020

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

MingKuan Lin, Research Assistant Professor, INOVA Neuroscience, School of Systems Biology, is working to measure gene expression levels in blood from patients undergoing treatment with buprenorphine for opioid use disorder.

22 Mar 2020

Study uncovers a new childhood-onset neurodegenerative disorder

A study has uncovered a new neurodegenerative disorder in which children experience developmental regression and severe epilepsy.

21 Mar 2020

DSI alumni use computational design to quickly discover treatments for COVID-19

Two graduates of the Data Science Institute at Columbia University are using computational design to quickly discover treatments for the coronavirus.

21 Mar 2020

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

Researchers at the Centro Nacional de Investigaciones Cardiovasculares, working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cells, the cells that line the interior of blood vessels.

21 Mar 2020