Gene News and Research

Latest Gene News and Research

DNA sequencing helps confirm breast cancer link between Leicester sisters

Two Leicester sisters who had their entire genomes sequenced in the hope of finding answers to their family history of breast cancer have learnt they both carry a genetic variant that significantly increases their risk of developing the disease.

27 Sep 2019

Anxiety-related behavior associated with disturbances in the cells' powerhouses

The powerhouse of the cell, the mitochondria, provides energy for cellular functions. But those activities can become disturbed when chronic stress leads to anxiety symptoms in mice and humans.

26 Sep 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Researcher aims to make CRISPR-Cas9 system safer and more precise

The mere mention of gene editing and DNA altering might conjure up images of designer babies, but that is not what researcher Jin Liu has in mind.

26 Sep 2019

University of Minnesota study finds link between stress and circadian clock health

The human body has an internal biological clock that is constantly running. Our well-being is dependent on the function of that clock. New research from the University of Minnesota Medical School found a little stress can make the circadian clock run better and faster.

26 Sep 2019

New discovery sheds light on how pancreatic cancer fuels its growth

A new discovery about pancreatic cancer sheds light on how the cancer fuels its growth and may help explain how promising cancer drugs work - and for whom they will fail.

26 Sep 2019

New NIH program aims to improve lives for people with inherited blood and immune diseases

People with inherited diseases of the blood and immune system can now receive treatment at the National Institutes of Health Clinical Center through a new, streamlined program that integrates expertise from many medical specialties and related basic science disciplines.

26 Sep 2019

Metabolite may predict cancer versus autism risk in PTEN patients

In a new study published in American Journal of Human Genetics, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may predict whether individuals with PTEN mutations will develop cancer or autism spectrum disorder.

26 Sep 2019

Temporal fluctuations in protein concentrations can determine fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount of certain proteins play a direct and significant role on biological processes.

26 Sep 2019

Study identifies 44 genes linked to age-related hearing loss

A new study published today in The American Journal of Human Genetics has identified 44 genes linked to age-related hearing loss giving a much clearer understanding of how the condition develops and potential treatments.

26 Sep 2019

AI technique helps detect people at risk of heart failure

Researchers have recently used an artificial intelligence (AL) technique to examine how MRI scans can validate how hereditary factors can impact heart function.

26 Sep 2019

Personal Genome Diagnostics applies CE mark to PGDx elio tissue complete assay

Personal Genome Diagnostics Inc. (PGDx), a leader in cancer genomics, today announced that it has applied the CE mark to the PGDx elio™ tissue complete assay.

26 Sep 2019

Late-breaking TAILORx data to be presented at ESMO Congress 2019

New data from TAILORx, the federally funded, phase three clinical trial, will be presented as late-breaking information at the European Society for Medical Oncology (ESMO) 2019 Congress in Barcelona, Spain.

26 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Pesticide exposure on the job related to more strokes, heart attacks

A new study published in the Journal of the American Heart Association, September 25, 2019, reports that the risk of cardiovascular disease (CVD) is increased by 42% in Japanese-American men exposed to high levels of pesticide. This is the first time this outcome has been explored in this group, and indicates that the role played by occupational pesticide exposure in the pathogenesis of CVD needs to be examined.

25 Sep 2019

Experimental treatment shows early promise to help nearly half of DMD patients

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy.

25 Sep 2019

Dormant HIV reservoirs could be killed with RNA switch

Researchers from the University of California San Diego School of Medicine have found cellular triggers within the immune cells that could be controlled in order to kill dormant HIV-1 reservoirs in individuals with HIV-1.

25 Sep 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Johns Hopkins researchers link a gene to melanoma growth and spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3.

From Johns Hopkins Medicine 25 Sep 2019