Gene News and Research

Latest Gene News and Research

Late-breaking TAILORx data to be presented at ESMO Congress 2019

New data from TAILORx, the federally funded, phase three clinical trial, will be presented as late-breaking information at the European Society for Medical Oncology (ESMO) 2019 Congress in Barcelona, Spain.

26 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Pesticide exposure on the job related to more strokes, heart attacks

A new study published in the Journal of the American Heart Association, September 25, 2019, reports that the risk of cardiovascular disease (CVD) is increased by 42% in Japanese-American men exposed to high levels of pesticide. This is the first time this outcome has been explored in this group, and indicates that the role played by occupational pesticide exposure in the pathogenesis of CVD needs to be examined.

25 Sep 2019

Experimental treatment shows early promise to help nearly half of DMD patients

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy.

25 Sep 2019

Dormant HIV reservoirs could be killed with RNA switch

Researchers from the University of California San Diego School of Medicine have found cellular triggers within the immune cells that could be controlled in order to kill dormant HIV-1 reservoirs in individuals with HIV-1.

25 Sep 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Johns Hopkins researchers link a gene to melanoma growth and spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3.

From Johns Hopkins Medicine 25 Sep 2019

AGS patients more likely to suffer from sexual dysfunction, shows study

AdrenoGenital Syndrome (AGS) encompasses a group of inherited metabolic disorders caused by a disruption in steroid hormone production in the adrenal cortex.

25 Sep 2019

Study on gene mutations may lead to better diagnosis and treatment for cancer

When a cell divides into two daughter cells, it must replicate its DNA according to a very specific scenario. In the presence of some disruptive elements, however, cancer cells are unable to perform this operation optimally; replication then takes place more slowly and less efficiently.

25 Sep 2019

Molecular changes are linked with adverse events following treatment of lymphatic filariasis

The Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported in PLOS Neglected Tropical Diseases that certain changes in gene expression are associated with these adverse events.

From PLOS ONE 25 Sep 2019

Study shows how AF4-MALS-UV can separate and size large AAV aggregates

Postnova Analytics has published a new applications study that reports on how Asymmetric Flow Field Flow Fractionation (AF4) coupled with multi-angle light scattering (MALS) and Ultraviolet (UV) detectors can be used to quantify Adeno-Associated Virus (AAV) aggregation.

From Postnova Analytics 25 Sep 2019

Space-based investigation helps address challenges involved in learning more about the human brain

Researchers studying neurological diseases face several daunting challenges. For one thing, these conditions may take years or even decades to develop.

25 Sep 2019

Love hormone oxytocin linked to hypersexuality

Sex addiction or hypersexual disorder is a behavior characterized by an excessive preoccupation with sexual fantasies, behaviors, or urges that are hard to control, causing negative effects on one’s health and relationships.

25 Sep 2019

7-year-old treated with FDA-approved gene therapy for Leber congenital amaurosis

When Zion Grant was 3 months old his mother Daisy Dodd noticed he wasn't tracking her with his eyes. Zion would fixate on a light in the room, but not on her face.

24 Sep 2019

Researchers identify key switch that eliminates dormant HIV reservoirs

Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned off or deleted, eliminates dormant HIV reservoirs.

24 Sep 2019

Iranian population is highly heterogeneous than previously believed, genome study shows

An international research team including scientists from the University of Cologne, Germany, numerous Iranian universities and the University of Sydney, Australia, has shown that today's Iranian population is composed of partially highly heterogeneous ethnic groups, exhibiting a high degree of genetic variation.

24 Sep 2019

The biological clock modulates immune response efficiency, study shows

According to a recent study published in Proceedings of the National Academy of Sciences of the United States of America, the biological clock influences immune response efficacy. Indeed, CD8 T cells, which are essential to fight infections and cancers, function very differently according to the time of day.

24 Sep 2019

Study identifies factor essential for tendon growth

Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery.

24 Sep 2019

Researchers explore risk of ALL in children with Down syndrome

Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome.

24 Sep 2019

Gene News and Research

Latest Gene News and Research

Late-breaking TAILORx data to be presented at ESMO Congress 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Pesticide exposure on the job related to more strokes, heart attacks

Experimental treatment shows early promise to help nearly half of DMD patients

Dormant HIV reservoirs could be killed with RNA switch

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Johns Hopkins researchers link a gene to melanoma growth and spread

AGS patients more likely to suffer from sexual dysfunction, shows study

Study on gene mutations may lead to better diagnosis and treatment for cancer

Molecular changes are linked with adverse events following treatment of lymphatic filariasis

Study shows how AF4-MALS-UV can separate and size large AAV aggregates

Space-based investigation helps address challenges involved in learning more about the human brain

Love hormone oxytocin linked to hypersexuality

7-year-old treated with FDA-approved gene therapy for Leber congenital amaurosis

Researchers identify key switch that eliminates dormant HIV reservoirs

Iranian population is highly heterogeneous than previously believed, genome study shows

The biological clock modulates immune response efficiency, study shows

Study identifies factor essential for tendon growth

Researchers explore risk of ALL in children with Down syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)