Gene News and Research

Latest Gene News and Research

ARMC5 regulates saturated and unsaturated fatty acid levels in fat cells

Researchers at Osaka University identified a degradation factor for SREBP1 as essential for maintaining the balance of saturated and unsaturated fatty acids in adipose tissue.

2 Dec 2024

Gut transit time and pH shape microbiome individuality and dietary responses

Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.

1 Dec 2024

RNA enzyme found key to heart cell energy shift after birth

Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.

29 Nov 2024

Scientists identify drug-resistant bone marrow cells linked to poor outcomes in fast-growing leukemia

Researchers explore treatment resistance and relapse in T-cell acute lymphoblastic leukemia.

29 Nov 2024

STAG2 loss linked to increased aggression in Ewing sarcoma

Ewing sarcoma is a tumor of the bones and soft tissues that occurs in children and young people. Like all childhood cancers, it is rare – 9 to 10 cases per million inhabitants per year – but it is very aggressive. 25% of patients do not respond well to regular therapy and they often experience relapses.

29 Nov 2024

Advanced microscopy reveals how ribosomes attach to mRNA for protein synthesis

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA.

28 Nov 2024

Research highlights long-term health effects of hormone therapy in transgender individuals

New research from Karolinska Institutet shows that long-term sex hormone treatment in transgender individuals can lead to significant changes in body composition and risk factors for cardiovascular disease, particularly in transgender men.

28 Nov 2024

Better maternal diet boosts brain growth and IQ in kids

Higher maternal diet quality during early pregnancy is associated with larger brain volumes and higher IQ scores in offspring aged 10 and 14. Editorial explains why prenatal nutrition plays a crucial role in long-term brain and cognitive development.

27 Nov 2024

Targeting intracellular checkpoints to enhance NK cell immunotherapy

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

27 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Stanford team uses natural cell death mechanism to kill cancer cells

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

27 Nov 2024

Study reveals protein mobility defect as a key factor in chronic diseases

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

27 Nov 2024

TRiC mutations found to cause developmental brain malformations in children

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

27 Nov 2024

Research shows "Alzheimer's in a dish" model can accelerate drug discovery

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks.

27 Nov 2024

Culturally appropriate interventions strengthen healthcare responses to domestic violence

Culturally appropriate women-centred interventions can help healthcare systems respond to domestic violence, research has found.

27 Nov 2024

New insights into cationic polymer structure in RNA drug delivery

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

27 Nov 2024

Depression increases chances of experiencing menstrual pain

Scientists investigate the genetic relationship between depression and dysmenorrhea.

27 Nov 2024

Unveiling INST10's role in neural development and cell identity

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development - which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

Cardiovascular disease risk linked to early brain decline in men

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier - from their mid 50s to mid 70s - than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Nov 2024