Gene News and Research

Latest Gene News and Research

Placental defects linked to congenital heart defects

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them.

26 Nov 2024

Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

First U.S. trial uses non-viral CRISPR to correct sickle cell mutation

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease.

26 Nov 2024

Tagomics announces a multiomic profiling co-marketing agreement with Agilent

Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced it has entered into a strategic co-marketing agreement with Agilent Technologies, a leading tools provider in the genomics sector.

From Tagomics Ltd. 26 Nov 2024

New insights into leptin's role in hypothalamic neural circuit development

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.

25 Nov 2024

Multiomic signatures identified for rapid detection and treatment of high-risk T-ALL

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients with acute lymphoblastic leukemia who have a higher risk version of the disease and are more likely to relapse despite treatment.

25 Nov 2024

Groundbreaking research sheds light on mitochondrial DNA depletion syndrome

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

25 Nov 2024

Researchers develop new approach to effectively deliver therapeutics into the brain

Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach - demonstrated in mouse models and isolated human brain tissue - to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases.

25 Nov 2024

Groundbreaking method profiles gene activity in the living brain

A groundbreaking method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Centre for Translational Brain Science and RCSI University of Medicine and Health Sciences, in collaboration with international partners.

25 Nov 2024

Deep learning revolutionizes RNA 3D structure prediction with RhoFold+

Researchers introduce RhoFold+, a groundbreaking deep learning model that predicts RNA 3D structures with unprecedented accuracy and efficiency, addressing critical challenges in structural biology.

24 Nov 2024

New study challenges the traditional view of gene switches

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA.

22 Nov 2024

Penn engineers cook up a new way for safer, more effective mRNA therapies

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids - key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies.

22 Nov 2024

Gene variant linked to early miscarriages identified

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

22 Nov 2024

Study sheds light on how cells repair damaged DNA

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells.

22 Nov 2024

Why predictive retina models could be the future of IND applications

Discover how retina models are revolutionizing rare disease treatment and accelerating drug development.

From Newcells Biotech 22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Fermented kimchi may help combat obesity by regulating gut microbiota

Kimchi consumption significantly reduces body fat and enhances metabolic indicators in overweight individuals, highlighting its role in obesity management.

22 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

Researchers reveal cellular foundations of functional brain networks in humans

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

21 Nov 2024

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024