Genetics News and Research

Latest Genetics News and Research

DNA barcoding shows how cancer cells evade the immune system's defenses

Some cancer cells can deploy parallel mechanisms to evade the immune system's defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.

7 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

UAB researchers report lack of predictability for fecal microbial transplants without prior antibiotic therapy

A fecal microbial transplant - giving a recipient fecal matter from a donor to change the recipient's gut microbial community in the colon - has been a successful last resort therapy for people with recurrent Clostridium difficile infection after multiple rounds of suppressive antibiotics have eliminated the recipient microbial community.

4 Nov 2022

New evaluation data shows the clinical utility of SOPHiA DDM Dx HRD Solution

SOPHiA GENETICS, a cloud-native software company in the healthcare space, debuted new data at the European Society of Gynaecological Oncology (ESGO) Congress as part of a poster (#PA-065) presented by Prof. Alexandre Harlé of the Institut de Cancérologie de Lorraine, France.

3 Nov 2022

Researchers provide insights on how to overcome resistance in cancer therapy

The latest developmental drugs, particularly for the use in oncology, rely on the targeted degradation of harmful pathogenic proteins.

3 Nov 2022

Parental discord linked to children's genetic risk for alcohol problems

Parents can transmit a genetic risk for alcohol problems to their children not only directly, but also indirectly via genetically influenced aspects of the home environment, such as marital discord or divorce, according to a Rutgers researcher.

3 Nov 2022

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse.

2 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

Social and economic inequality associated with differences in children's brain connections

Growing up in a socioeconomically disadvantaged household may have lasting effects on children's brain development, a large new study suggests.

1 Nov 2022

SARS-CoV-2 can disrupt normal mix of gut bacteria to increase risk for other infections

Infection with the pandemic virus, SARS-CoV-2, can reduce the number of bacterial species in a patient's gut, with the lesser diversity creating space for dangerous microbes to thrive, a new study finds.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

Polygenic hazard score could be effective for predicting genetic risk of lethal prostate cancer

Tapping into the Million Veteran Program, an ongoing national research effort to learn how genes, lifestyle and military exposures affect the health of participants, researchers at University of California San Diego School of Medicine and the VA San Diego Healthcare System, with colleagues elsewhere, report that a polygenic hazard score based on 290 genetic variants could be an effective tool for predicting genetic risk of lethal prostate cancer.

31 Oct 2022

Ancient genomes shed light on previously unknown aspect of human evolution

The use of ancient DNA, including samples of human remains around 45,000 years old, has shed light on a previously unknown aspect of human evolution.

31 Oct 2022

Scientists reveal anti-inflammatory molecules that play an important role in aging

Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process - a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

31 Oct 2022

Does maternal obesity impact fetal brain development?

In a new study, researchers assessed the impact of maternal obesity on brain development in the fetus.

31 Oct 2022

The impact of genetic and lifestyle factors on the risk of major cardiovascular and thromboembolic events post-COVID-19 diagnosis

A new study aimed to analyze the association between lifestyle risk factors, PRSs, and their interactions along with the risk of CVE within 90 days post-COVID-19 diagnosis.

31 Oct 2022

Genetics News and Research

Latest Genetics News and Research

DNA barcoding shows how cancer cells evade the immune system's defenses

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

UAB researchers report lack of predictability for fecal microbial transplants without prior antibiotic therapy

New evaluation data shows the clinical utility of SOPHiA DDM Dx HRD Solution

Researchers provide insights on how to overcome resistance in cancer therapy

Parental discord linked to children's genetic risk for alcohol problems

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Social and economic inequality associated with differences in children's brain connections

SARS-CoV-2 can disrupt normal mix of gut bacteria to increase risk for other infections

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

Polygenic hazard score could be effective for predicting genetic risk of lethal prostate cancer

Ancient genomes shed light on previously unknown aspect of human evolution

Scientists reveal anti-inflammatory molecules that play an important role in aging

Does maternal obesity impact fetal brain development?

The impact of genetic and lifestyle factors on the risk of major cardiovascular and thromboembolic events post-COVID-19 diagnosis

Faulty gene may explain why some people gain excessive weight despite normal food intake

Study provides new insights into genetic form of frontotemporal dementia

Brain Canada Foundation funds future leaders in Canadian brain research

Sequencing & Genomics: Elevating Science and Healthcare eBook

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics