Genetics News and Research

Latest Genetics News and Research

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

An investigational drug is producing powerful responses in patients resistant to Gleevec, the targeted therapy that helps most people diagnosed with chronic myeloid leukemia (CML), an international research team headed by investigators at The University of Texas M. D. Anderson Cancer Center is reporting.

23 Apr 2005

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Maxim Pharmaceuticals have announced the United States Patent and Trademark Office issued U.S. patent number 6,828,091 B2, entitled "Method of Identifying Immunosuppressive Agents."

23 Apr 2005

Canadian Diabetes Association, UBC partner on funding for childhood diabetes research

A new partnership announced by the Canadian Diabetes Association and the University of British Columbia (UBC) will help fund research in childhood diabetes. Not only will this research further investigate type 1 diabetes, it will also explore the areas of type 2 diabetes and obesity in children, a problem of growing concern and proportions.

23 Apr 2005

Breakthrough technology that identifies molecular markers in early lung cancer

The new technology, created in collaboration with SEQUENOM, developers of genetic analysis products, and Methexis Genomics, uses a DNA analysis technique called methylation profiling to detect cells in the lung that are likely to become cancerous.

23 Apr 2005

Pregnant women with epilepsy face dilemma - continue treatment and risk birth defects

An article in the journal Epilepsia reviewed recent data on the risks associated with continuation of medical treatment of women with epilepsy during their pregnancies.

22 Apr 2005

Genetic variation linked to alcohol dependence

The same gene that accounts for part of a genetic risk for developing alcoholism in a U.S. population is found in a Russian population, according to a published study by a Yale School of Medicine researcher.

22 Apr 2005

Brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism

A new mouse study suggests that a brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism. Mice with a mutation in a gene called "Clock," which helps drive circadian rhythm, ate significantly more and gained more weight.

22 Apr 2005

One step closer to personalized medical treatment

A new study by 64 renowned scientists may bring us one step closer to personalized medical treatment--that is, medical treatment tailored to each person's unique genetic make-up and medical condition.

22 Apr 2005

New strategy to identify differences between non-metastatic and highly metastatic breast cancer cells

Researchers at the University of California, San Diego have used a new strategy to identify differences between non-metastatic and highly metastatic breast cancer cells. The article by Valerie Montel et al., "Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model," appears in the May 2005 issue of The American Journal of Pathology and is accompanied by a commentary.

22 Apr 2005

Enzyme that helps trigger the development of leukemia

Scientists at the University of North Carolina at Chapel Hill have identified an enzyme that helps trigger the development of leukemia, a cancer of blood cells.

21 Apr 2005

Discovery may lead to new drugs to prevent sexually transmitted HIV infection

Scientists have long suspected that HIV hijacks immune cells called dendritic cells to infiltrate the immune system. Now UCLA AIDS Institute researchers have shown that blocking HIV's access to a naturally occurring molecule on dendritic cells may cut their ability to smuggle the virus into other immune cells.

21 Apr 2005

Neural tube defects decrease with folic acid fortification

A new study published online April 21, 2005 in the American Journal of Medical Genetics Part A examines whether the recent decline in neural tube defects in Chile was due to the addition of folic acid to wheat flour in that country or to pre-existing decreasing trends. The journal is available online via Wiley InterScience.

21 Apr 2005

First time video capture of chemical signals that traverse human cells messaging

Researchers at UCSD and UC Irvine have captured on video for the first time chemical signals that traverse human cells in response to tiny mechanical jabs, like waves spreading from pebbles tossed into a pond. The scientists released the videos and technical details that explain how the visualization effect was created as part of a paper published in the April 21 issue of Nature.

21 Apr 2005

Body's 24-hour internal clock linked to obesity and diabetes

Obesity and diabetes in both adults and children are rising at alarming rates and a wide range of culprits -- super-sized food portions, lack of exercise due to television, computers, suburban sprawl and loss of gym classes, high-fat and fast foods, sugar-laden drinks and psychological trauma -- have been blamed.

21 Apr 2005

Gene may boost schizophrenia risk

Clues about how a suspect version of a gene may slightly increase risk for schizophrenia are emerging from a brain imaging study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). The gene variant produced a telltale pattern of activity linked to production of a key brain messenger chemical.

21 Apr 2005

Genes influence how heart failure patients respond to drugs

Genes dictate the color of our hair and eyes. They factor into whether we get cancer or heart disease. And, scientists increasingly recognize, they also ensure some patients will benefit from a prescription drug, while others develop adverse reactions or simply fail to respond at all.

21 Apr 2005

Inherited variations in mitochondrial DNA linked to renal and prostate cancer

More than 20 million men in the United States with a particular signature set of inherited characteristics and mutations in mitochondrial DNA (mtDNA) are at significantly increased risk for developing renal and prostate cancers, according to research at Emory University.

20 Apr 2005

RNA interference permanently silences key breast cancer gene

In laboratory mouse experiments, researchers at The University of Texas M. D. Anderson Cancer Center have developed a way to use RNA interference (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences activated STAT3, a crucial gene found in some human breast tumors, thus reducing the cancer's ability to become invasive.

20 Apr 2005

New gene linked to familial cancer

Scientists have identified a new gene that appears to be linked to a small but significant percentage of familial cancer cases – as well as seemingly randomly occurring malignancies.

20 Apr 2005

Green tea appears to prevent cancer in men

After a year's oral administration of green tea catechins (GTCs), only one man in a group of 32 at high risk for prostate cancer developed the disease, compared to nine out of 30 in a control, according to a team of Italian researchers from the University of Parma and University of Modena and Reggio Emilia led by Saverio Bettuzzi, Ph.D.

20 Apr 2005

Genetics News and Research

Latest Genetics News and Research

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Canadian Diabetes Association, UBC partner on funding for childhood diabetes research

Breakthrough technology that identifies molecular markers in early lung cancer

Pregnant women with epilepsy face dilemma - continue treatment and risk birth defects

Genetic variation linked to alcohol dependence

Brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism

One step closer to personalized medical treatment

New strategy to identify differences between non-metastatic and highly metastatic breast cancer cells

Enzyme that helps trigger the development of leukemia

Discovery may lead to new drugs to prevent sexually transmitted HIV infection

Neural tube defects decrease with folic acid fortification

First time video capture of chemical signals that traverse human cells messaging

Body's 24-hour internal clock linked to obesity and diabetes

Gene may boost schizophrenia risk

Genes influence how heart failure patients respond to drugs

Inherited variations in mitochondrial DNA linked to renal and prostate cancer

RNA interference permanently silences key breast cancer gene

New gene linked to familial cancer

Green tea appears to prevent cancer in men

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