Genetics News and Research

Latest Genetics News and Research

Vertex, Genomics team up to improve discovery of precision medicines

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Genomics plc today announced a three-year collaboration, extendable to five years, to use human genetics and machine learning to improve discovery of targets for precision medicines, and to advance understanding of the clinical impact of human genetic variation and patient stratification in diseases with significant unmet need.

30 Aug 2018

$Genetics study uncovers key factors for fracture risk in osteoporosis$

Genetics study uncovers key factors for fracture risk in osteoporosis

The largest study ever to investigate the genetics of osteoporosis and fracture risk determined that only two examined factors - bone mineral density and muscle strength - play a potentially causal role in the risk of suffering osteoporotic fracture, a major health problem affecting more than 9 million people worldwide very year.

30 Aug 2018

Study opens new avenues for engineering smells and tastes

Every smell, from a rose to a smoky fire to a pungent fish, is composed of a mixture of odorant molecules that bind to protein receptors inside your nose.

30 Aug 2018

$Genome-wide association study provides insight into biologic mechanisms leading to fractures$

Genome-wide association study provides insight into biologic mechanisms leading to fractures

A paper titled "Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomization study" appeared today in the British Medical Journal.

30 Aug 2018

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Stephen Elledge, PhD, and his team did not set out to find therapies that could render tumors less resistant to therapy or make existing drugs more potent against a rare form of cancer. But these are precisely the clinical insights that their most recent study has yielded.

29 Aug 2018

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing - the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors.

29 Aug 2018

Research shows proteomics can be used to predict evolution of triple negative breast cancer

The rarest, but also the most aggressive and hard to treat form of breast cancer, is known as triple negative. For this type of cancer, researchers have so far been unable to identify markers that can classify patients by prognosis or probability of responding to different treatments.

29 Aug 2018

New study suggests chemotherapy may cause early menopause in women with lung cancer

A new study suggests chemotherapy may cause acute amenorrhea leading to early menopause in women with lung cancer.

29 Aug 2018

The connection between brain anatomy, genes and obesity

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

29 Aug 2018

Cannabis use and mental illness link found

A large new study has found that people with mental ailments such as schizophrenia are more genetically inclined to use cannabis.

29 Aug 2018

Pediatric researchers discover gene mutation that causes lymphatic disorder

Pediatric researchers have identified a gene mutation that causes a serious lymphatic condition, and used that knowledge to restore normal lymphatic vessels in model animals. The laboratory findings may lead to a new therapy for patients with this type of abnormal lymphatic circulation.

28 Aug 2018

Research solves mystery on nature of EGFR signaling and how it drives development

What do cancer and the growing legs of a fruit fly have in common? They can both be influenced by a single molecule, a protein that tends to call the shots inside of embryos as they develop into living, breathing animals.

28 Aug 2018

Studies on fruit flies reveal new findings of how neurons in the brain function

Studies of the song of the fruit flies reveal new findings of how the neurons in the brain function. These results can be used to uncover new knowledge on how brains in general function which in the longer term may have medical significance.

25 Aug 2018

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Inhibition of miR-24-3p reduced growth of cancer cells and was found to regulate proteins as a potential treatment target for Mesothelioma.

25 Aug 2018

Research into biology behind sperm development could offer hope for solving male infertility

Nearly one in eight couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner.

24 Aug 2018

MSU researchers move one step closer to solving arthritic disease in teenagers

A new Michigan State University study has found that a malfunctioning gene associated with a common arthritic disease that often starts in teenagers is now directly linked to the loss of vital immune cells that may prevent it.

24 Aug 2018

Genetic interindividual variability influences nutritional requirements

Approximately 0.1%: that is the average genetic difference between two individuals. This small percentage is responsible for the variations of certain physical traits, such as eyes, hair, and height, but also for differences in our susceptibility to certain diseases and our capacity to absorb vitamins and phytomicronutrients, involved in the prevention of chronic disease.

24 Aug 2018

Advanced microscopes determine structure of molecular complex implicated in several cancers

In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers.

24 Aug 2018

People fall into trap of greater inactivity during middle age, research reveals

People are falling into a trap of greater inactivity during middle age, according to new research from The University of Texas Health Science Center at Houston, which calls for its findings to be considered in future national physical activity guidelines.

24 Aug 2018

Genetics News and Research

Latest Genetics News and Research

Vertex, Genomics team up to improve discovery of precision medicines

Genetics study uncovers key factors for fracture risk in osteoporosis

Study opens new avenues for engineering smells and tastes

Genome-wide association study provides insight into biologic mechanisms leading to fractures

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Research shows proteomics can be used to predict evolution of triple negative breast cancer

New study suggests chemotherapy may cause early menopause in women with lung cancer

The connection between brain anatomy, genes and obesity

Cannabis use and mental illness link found

Pediatric researchers discover gene mutation that causes lymphatic disorder

Research solves mystery on nature of EGFR signaling and how it drives development

Studies on fruit flies reveal new findings of how neurons in the brain function

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Research into biology behind sperm development could offer hope for solving male infertility

MSU researchers move one step closer to solving arthritic disease in teenagers

Genetic interindividual variability influences nutritional requirements

Advanced microscopes determine structure of molecular complex implicated in several cancers

People fall into trap of greater inactivity during middle age, research reveals

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