Genetics News and Research

Latest Genetics News and Research

Paper details new target for anti-cancer drug development

In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ends of our DNA.

25 Oct 2012

UNM Cancer Center scientist to continue histone modification study

While every one of our cells contains all of our genetic information, each type of cell uses only specific parts of that information to make its proteins. Uncovering more about the mechanism that directs which particular pieces of genetic information the cell uses is the research focus of Mary Ann Osley, PhD, University of New Mexico Professor of Molecular Genetics and Microbiology and Co-Leader of the Cancer Biology and Biotechnology Program at the UNM Cancer Center.

24 Oct 2012

New biomarker measures aggressiveness of primary prostate tumors

Research out of Roswell Park Cancer Institute (RPCI) supports the adoption of a new biomarker to measure the aggressiveness of primary prostate tumors.

24 Oct 2012

Novel approach to assemble the 'connectome' via genetic barcoding

A team of neuroscientists has proposed a new and potentially revolutionary way of obtaining a neuronal connectivity map (the "connectome") of the whole brain of the mouse. The details are set forth in an essay published October 23 in the open-access journal PLOS Biology.

24 Oct 2012

Link between autism spectrum disorders and schizophrenia

Autism Spectrum Disorders (ASD), a category that includes autism, Asperger Syndrome, and Pervasive Developmental Disorder, are characterized by difficulty with social interaction and communication, or repetitive behaviors. The U.S. Centers for Disease Control and Management says that one in 88 children in the US is somewhere on the Autism spectrum - an alarming ten-fold increase in the last four decades.

24 Oct 2012

Austrian researchers receive $7.4 million award to verify new breast cancer pathways

The innovator's award recognises Josef Penninger's work in identifying a key molecular pathway how hormone replacement therapies and contraceptive pills can lead to breast cancer. His team provided the first genetic proof that a protein called RANKL is the master regulator of bone loss, which has contributed to the development of a novel drug already approved for the treatment of osteoporosis and skeletal related events in multiple cancers.

23 Oct 2012

Breast cancer spread dependent on both environment and genetic changes

A new study from Johns Hopkins researchers suggests that the lethal spread of breast cancer is as dependent on a tumor’s protein-rich environment as on genetic changes inside tumor cells.

23 Oct 2012

Thin ideal internalization: an interview with Jessica Suisman and Kelly Klump

Thin-ideal internalization is the extent to which a person identifies with the cultural ideal that thinness is equivalent to attractiveness.

23 Oct 2012

Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

New approach to prevention of breast cancer wins $7.4M award

A new approach to possible future prevention of breast cancer and slowing the spread of tumours has won Austrian researcher Josef Penninger, director of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) in Vienna, a $7.4 million innovator's award to continue his research, from the USA's Congressionally Directed Medical Research Program.

22 Oct 2012

Insight into calcium pumps in cells

When animals and plants are exposed to influences such as bacterial attack, odour and cold, calcium ions flow into the cells. The calcium provides the cells with a signal about what is going on outside, but as high concentrations of calcium are toxic to the cells, it must be quickly pumped out again.

22 Oct 2012

Epigenetic alteration associated with increased risk of breast cancer

Monozygotic twins have the same genome, that is, the same DNA molecule in both siblings. Despite being genetically identical, both twins may have different diseases at different times. This phenomenon is called "twin discordance". But how can people who have the same genetic sequence present different pathologies and at different ages? The explanation partly lies in the fact that the chemical signals added in the DNA to "switch off" or "switch on" genes can be different. These signals are known as epigenetic marks.

20 Oct 2012

AMP report provides overview of next generation sequencing technology

The Association for Molecular Pathology published the report of the Whole Genome Analysis Working Group of the AMP Clinical Practice Committee in the November 2012 issue of The Journal of Molecular Diagnostics.

20 Oct 2012

Common misconceptions about breast cancer risks

From the food we eat to the products we use, there are a lot of misconceptions about what may increase the risk of developing breast cancer. There are known factors, like genetics, that are well documented. But what about lifestyle issues like having a nightly cocktail or using deodorant? So, what is fact and what is fiction? Wendy Chen, MD, MPH, a breast cancer expert at Dana-Farber Cancer Institute in Boston says an overabundance of information can be confusing, and it often is incorrect to some degree.

20 Oct 2012

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers at the Salk Institute for Biological Studies have identified damage to neural stem cells as a powerful player in the disease.

20 Oct 2012

New video on how to handle Malignant Hyperthermia crisis now available from MHAUS

New video on how to handle a Malignant Hyperthermia crisis is now available from the Malignant Hyperthermia Association of the United States.

20 Oct 2012

Childhood poverty, demographics associated with DNA methylation patterns

A University of British Columbia and Centre for Molecular Medicine and Therapeutics (CMMT) study has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, all leave an imprint on a person's genes. And, that this imprint could play a role in our immune response.

20 Oct 2012

New study decodes complete epigenome of chronic lymphocytic leukemia

Researchers of the University of Oviedo have contributed to decipher the first epigenomes of chronic lymphocytic leukemia.

20 Oct 2012

Two Chicago students develop novel treatment method for fetal alcohol syndrome

Two Chicago high school students have developed a novel treatment method to reduce the negative effects of Fetal Alcohol Syndrome (FAS) and a new understanding of genetics behind the disease.

19 Oct 2012

Book about triple negative breast cancer

Hope, Treatment, and Recovery by Patricia Prijatel is exactly that-an encouraging guide to surviving a disease often referred to as, "a particularly aggressive and difficult to treat form of cancer." Prijatel is a health journalist who, at the age of 60 was diagnosed with triple negative breast cancer [TNBC] a disease which disproportionately affects young women and women of African descent. No book existed on TNBC at the time of Prijatel's diagnosis.

19 Oct 2012