Gout News and Research

Latest Gout News and Research

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

While hospitalizations related to rheumatoid arthritis have dropped considerably over the past two decades, hospitalizations primarily associated with gout have increased dramatically.

8 Jun 2016

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Drinking tart Montmorency cherry juice significantly reduces high blood pressure at a level comparable to that achieved by medication, according to new research from Northumbria University, Newcastle.

6 May 2016

High-fructose diet during pregnancy may affect fetal growth

Consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life, according to research in mice and people by a team at Washington University School of Medicine in St. Louis.

5 May 2016

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

A multi-institutional study led by a Massachusetts General Hospital investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, sometimes life-threatening adverse reaction to the most commonly prescribed medication. The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

16 Apr 2016

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

Using a combination of newly developed methods, researchers led by Ludwig-Maximilians-Universitaet (LMU) in Munich immunologist Veit Hornung have defined a previously unknown pathway that triggers inflammation.

31 Mar 2016

New thematic issue highlights link between hyperuricemia, gout and kidney disease

The increasing prevalence of both gout and chronic kidney disease has led to a growing interest in the association between hyperuricemia (an abnormally high level of uric acid in the blood) and kidney disease.

29 Mar 2016

Intense physical work helped Michelangelo combat arthritis

Prolonged hammering and chiselling accelerated degenerative arthritis in the hands of Michelangelo Buonarroti, sculptor, painter and one of the greatest artists of all time. But the intense work probably helped him keep the use of his hands right up until he died. That is the conclusion of doctors writing in the Journal of the Royal Society of Medicine who analysed three portraits of the artist to reach their diagnosis.

5 Feb 2016

LMU researchers reveal how crystalline deposits induce cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now elucidated how the insoluble deposits induce cell death.

29 Jan 2016

Study throws light on why gout not well managed in many patients

A study published online this month in the Arthritis Care and Research journal is shedding light on why gout, a painful and common form of arthritis, is not well managed in many patients. The journal is published by the American College of Rheumatology.

22 Jan 2016

Common painkiller diclofenac has significant anti-cancer properties

Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.

12 Jan 2016

Study advances understanding of chronic and progressive nature of gout if treated inadequately

Emeritus professor of medicine, Elisio Pascual, at the Miguel Hernández Univeristy in Elche and former head of the Rheumatology Unit at Alicante University Hospital has published a research paper presenting previously unknown data that contribute to our understanding of gout as a crystal deposition disease.

29 Dec 2015

Positive interim results from TWIB's AC-201 CR Phase 2 study for hyperuricemia and gout

TWi Biotechnology Inc. today announced interim results from the ongoing Phase 2 proof of concept clinical study evaluating AC-201 CR as an oral uricosuric and anti-inflammatory agent for the treatment of hyperuricemia and prevention of gout flares combining with febuxostat, a xanthine oxidase inhibitor.

24 Dec 2015

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body.

22 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

9 Nov 2015

Sleep apnea may increase gout risk

Sleep apnea may increase the risk of developing gout, a new study shows. Among 9865 patients with newly-diagnosed sleep apnea and 43,598 comparators of similar weight, investigators identified 270 new cases of gout over one year of follow-up, resulting in incidence rates of 8.4/1000 and 4.8/1000 person-years, respectively. The increased risk of gout was 60% higher among patients with sleep apnea.

20 Oct 2015

Gout News and Research

Latest Gout News and Research

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

High-fructose diet during pregnancy may affect fetal growth

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

New thematic issue highlights link between hyperuricemia, gout and kidney disease

Intense physical work helped Michelangelo combat arthritis

LMU researchers reveal how crystalline deposits induce cell death

Study throws light on why gout not well managed in many patients

Common painkiller diclofenac has significant anti-cancer properties

Study advances understanding of chronic and progressive nature of gout if treated inadequately

Positive interim results from TWIB's AC-201 CR Phase 2 study for hyperuricemia and gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

NEK7 enzyme acts as on-off switch in innate immune system

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

Sleep apnea may increase gout risk

Experts and researchers develop new classification criteria for gout

UT Southwestern evaluates allopurinol drug to prevent nephropathy in Type I diabetes patients

ACR releases two new publications to improve treatment of polymyalgia rheumatica, gout

ESC publishes new guidelines on pericardial diseases

Industry Focus: Cell & Gene Therapy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Gout News and Research

Latest Gout News and Research

Industry Focus: Cell & Gene Therapy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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