Gout

Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.

Overview

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Latest Gout News and Research

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What is the risk of SARS-CoV-2 infection among gout patients?

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Gout medicine fails to improve cardiovascular outcomes in patients with ischemic heart disease

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Researchers unravel a novel molecular target of eicosapentaenoic acid

Gout flares associated with subsequent cardiovascular events

Gout flares associated with subsequent cardiovascular events

Low doses of a less commonly used drug may be a better treatment option for gout

Low doses of a less commonly used drug may be a better treatment option for gout

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Novel genetic mapping study traces links between DNA variations and blood proteins

Probenecid shows activity against respiratory syncytial virus

Probenecid shows activity against respiratory syncytial virus

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Using customized 'mini-antibodies' to mitigate chronic inflammation

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Exploring biomedical literature and clinical trial records to identify new drug combinations for COVID-19 treatment

EULAR develops new recommendations for cardiovascular risk management

EULAR develops new recommendations for cardiovascular risk management

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Colchicine holds promise to reduce the risk of severe COVID-19

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MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

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Anti-inflammatory drug used to treat gout does not reduce the risk of COVID-19 mortality

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Is gout a risk factor for COVID-19?

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Limited evidence colchicine reduces COVID-19 related hospitalization

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UGA research offers hope for a viable therapeutic to combat COVID-19

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