Gout

Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.
Gout: an Overview

Gout is a form of arthritis that causes inflammation and severe pain in joints such as the knee, foot, ankle or wrist and particularly in the base of the big toe.

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Overview

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Latest Gout News and Research

The cost of excessive sugar in the diet

The cost of excessive sugar in the diet

Dietary sugar has negative impact on health independent of obesity

Dietary sugar has negative impact on health independent of obesity

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Antihypertensive drug associated with lower risk of gout

Antihypertensive drug associated with lower risk of gout

New wearable sensor for non-invasive gout detection

New wearable sensor for non-invasive gout detection

BU researcher receives NIH grant for clinical research in rheumatology

BU researcher receives NIH grant for clinical research in rheumatology

New genome-wide association study shines light on genetic risk factors for gout

New genome-wide association study shines light on genetic risk factors for gout

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

Common gout medications can kill elephantiasis-causing parasites

Common gout medications can kill elephantiasis-causing parasites

Study: Heart disease is associated with allopurinol-related severe skin reactions

Study: Heart disease is associated with allopurinol-related severe skin reactions

Obesity stigma and yo-yo dieting, not BMI, are behind chronic health conditions, dietitian claims

Obesity stigma and yo-yo dieting, not BMI, are behind chronic health conditions, dietitian claims

Survey says half of people with rheumatoid disease struggle to pay for treatment

Survey says half of people with rheumatoid disease struggle to pay for treatment

Modifiable risk factors play key roles in the development of gout

Modifiable risk factors play key roles in the development of gout

Danish-American researchers find new way to treat chronic inflammation

Danish-American researchers find new way to treat chronic inflammation

Gout patients have higher risk of advanced kidney disease, study finds

Gout patients have higher risk of advanced kidney disease, study finds

Polycystic kidney disease may be preventable

Polycystic kidney disease may be preventable

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

Company expands development plans for drugs which slow progression to dialysis

Company expands development plans for drugs which slow progression to dialysis

Montmorency tart cherry juice may help improve cognitive performance in older adults

Montmorency tart cherry juice may help improve cognitive performance in older adults

Study reports significant link between exposure to inorganic dust and gout in women

Study reports significant link between exposure to inorganic dust and gout in women