Gout

Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.

Overview

Feature Articles

Latest Gout News and Research

MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

Anti-inflammatory drug used to treat gout does not reduce the risk of COVID-19 mortality

Anti-inflammatory drug used to treat gout does not reduce the risk of COVID-19 mortality

Is gout a risk factor for COVID-19?

Is gout a risk factor for COVID-19?

Limited evidence colchicine reduces COVID-19 related hospitalization

Limited evidence colchicine reduces COVID-19 related hospitalization

UGA research offers hope for a viable therapeutic to combat COVID-19

UGA research offers hope for a viable therapeutic to combat COVID-19

Researchers explore the fate of dietary fructose in the body

Researchers explore the fate of dietary fructose in the body

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

“React and inject”: synthetic peptide-modified nanodiamonds as emergency pan-coronavirus vaccines

“React and inject”: synthetic peptide-modified nanodiamonds as emergency pan-coronavirus vaccines

The impact of COVID-19 on dialysis patients

The impact of COVID-19 on dialysis patients

New recommendations on the use of intra-articular therapies

New recommendations on the use of intra-articular therapies

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

Repurposed gout medication (probenecid) shows potent inhibition of SARS-CoV-2 replication

Repurposed gout medication (probenecid) shows potent inhibition of SARS-CoV-2 replication

Combining two medications doubles gout treatment success, study reveals

Combining two medications doubles gout treatment success, study reveals

Many adults with hypertension may be taking other medications that could raise blood pressure

Many adults with hypertension may be taking other medications that could raise blood pressure

The FDA seeks a new way to review old drugs without causing prices to soar

The FDA seeks a new way to review old drugs without causing prices to soar

Inhibition of NLRP3 complex  can reduce inflammation in melanoma patients

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

Scientists seek Covid treatment answers in cheap, older drugs

Scientists seek Covid treatment answers in cheap, older drugs

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

Can early use of colchicine reduce COVID-19 mortality?

Can early use of colchicine reduce COVID-19 mortality?