Gout

Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.

Overview

Feature Articles

Latest Gout News and Research

Inhibition of NLRP3 complex  can reduce inflammation in melanoma patients

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

Scientists seek Covid treatment answers in cheap, older drugs

Scientists seek Covid treatment answers in cheap, older drugs

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

Can early use of colchicine reduce COVID-19 mortality?

Can early use of colchicine reduce COVID-19 mortality?

Crafoord Laureate uncovered a new group of rare autoinflammatory diseases

Crafoord Laureate uncovered a new group of rare autoinflammatory diseases

Colchicine may have therapeutic potential against COVID-19

Colchicine may have therapeutic potential against COVID-19

Rheumatoid arthritis may increase risk of dying from COVID-19

Rheumatoid arthritis may increase risk of dying from COVID-19

Telemedicine appointment cancellations were almost zero during the COVID phase

Telemedicine appointment cancellations were almost zero during the COVID phase

Oral methotrexate can be an effective intervention for people with knee OA

Oral methotrexate can be an effective intervention for people with knee OA

Study explains the global burden of disability from musculoskeletal conditions

Study explains the global burden of disability from musculoskeletal conditions

Extreme levels of serum uric acid linked to substantial reduction in patient survival

Extreme levels of serum uric acid linked to substantial reduction in patient survival

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

New multiplexed test with a low-cost sensor may enable at-home COVID diagnosis

New multiplexed test with a low-cost sensor may enable at-home COVID diagnosis

Study finds how different strategies may impact clinical trial enrollment

Study finds how different strategies may impact clinical trial enrollment

High fructose corn syrup increases risk factors for heart disease, diabetes

High fructose corn syrup increases risk factors for heart disease, diabetes

Gout medication reduces major cardiovascular events in heart patients

Gout medication reduces major cardiovascular events in heart patients

Gout drug may improve heart function in individuals with congenital heart disease

Gout drug may improve heart function in individuals with congenital heart disease

Combination of gout and diabetes carries increased risk of amputation

Combination of gout and diabetes carries increased risk of amputation

Gout diagnoses increased dramatically from 1990 to 2017, shows new analysis

Gout diagnoses increased dramatically from 1990 to 2017, shows new analysis