Heart Disease News and Research

Latest Heart Disease News and Research

Study: Protein's structural arrangement can change its signaling function

In a joint study, scientists from the California and Florida campuses of The Scripps Research Institute have shown that changes in a protein's structure can change its signaling function and they have pinpointed the precise regions where those changes take place.

8 Sep 2011

Adding azithromycin to usual daily treatment for COPD reduces acute exacerbations by 27%

Richard Casaburi, Ph.D., M.D., principal investigator at Los Angeles Biomedical Research Institute (LA BioMed), is co-author of a recent study that should help improve the condition for the millions of individuals who suffer from chronic obstructive pulmonary disease, better known as COPD.

8 Sep 2011

Top-line results from Teva-Alcobra MG01CI Phase II trial for ADHD

Teva Pharmaceutical Industries Ltd. and Alcobra Ltd. announced today top-line results from a six week, randomized, placebo-controlled, Phase II multi-center study designed to assess the safety and efficacy of MG01CI in adults with attention deficit hyperactivity disorder (ADHD).

7 Sep 2011

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

Ardea Biosciences, Inc. announced that it has completed formal End-of-Phase 2 meetings with the U.S. Food and Drug Administration (FDA) and successfully reached agreement on the following key aspects of its proposed lesinurad Phase 3 development plan: the overall size and design of the planned Phase 3 clinical studies, the primary endpoints, the total safety database proposed for NDA filing, manufacturing plans for both drug substance and drug product, the preclinical toxicology program and the clinical pharmacology program.

7 Sep 2011

St. Jude Medical receives approval for CRT-D quadripolar pacing system in India

St. Jude Medical, Inc., a global medical device company, today announced the approval of the industry's first quadripolar pacing system for cardiac resynchronization therapy defibrillators (CRT-Ds) in India. The Promote Quadra CRT-D offers physicians the ability to more effectively and efficiently manage the ever-changing pacing needs of patients with heart failure.

7 Sep 2011

International researchers to assess role of pre-clinical animal models in drug discovery

The New York Academy of Sciences and the Global Medical Excellence Cluster (GMEC), in collaboration with Imperial College London and King's College London, will host a two-day scientific conference, "Animal Models and Their Value in Predicting Drug Efficacy and Toxicity," that will provide a forum to critically examine the role of pre-clinical animal models in drug discovery.

7 Sep 2011

Individuals with excess BMI more likely to develop type 2 diabetes

Obesity is a known risk factor for developing type 2 diabetes. But it hasn't been clear whether the "dose" of obesity—how much excess weight a person has, and for how long—affects the risk of diabetes.

7 Sep 2011

Patient quality, care coordination programs surface in California

The University of California, San Francisco's heart failure program is an effort to reduce repeat hospitalizations by giving patients plenty of information and support to help them after they are discharged. Since the program began three years ago, the hospital's readmission rate has dropped by 30 percent. The hospital says the program has also saved Medicare at least $1 million a year.

7 Sep 2011

Cheap medicines could prevent huge number of deaths from heart attacks, strokes

A major new international study involving researchers from the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital has revealed that aspirin, statins, beta blockers and ACE inhibitors are prescribed far too infrequently. They are cheap, preventive medicines that could prevent a huge number of deaths from heart attacks and strokes.

7 Sep 2011

New Vital Signs report finds decline in cigarette smoking among American adults

Fewer American adults are smoking cigarettes, according to a new Vital Signs report from the Centers for Disease Control and Prevention. Also, daily smokers are smoking fewer cigarettes each day, it says.

7 Sep 2011

March of Dimes urges all pregnant women to get influenza immunization

Getting a flu shot during pregnancy protects the mom-to-be from what could be a very serious – even fatal – illness and can protect her newborn who is too young to receive his or her own immunization.

7 Sep 2011

Researchers investigate special diets that could help youngsters keep the weight off

A shocking 17 per cent of boys and 15 per cent of girls aged two to 15 years are obese in the UK, putting them at risk of serious, long-term health problems. Now a team of Aberdeen researchers are investigating special diets which could help youngsters keep the weight off, thanks to a grant from children's charity Action Medical Research.

7 Sep 2011

Diabetes prevention in five steps: Study

According to a new study meeting just one of five key health goals reduces the odds of developing diabetes in middle age by roughly one-third. The report adds that the more goals are met the lower the risk falls, even if there is a family history of diabetes.

6 Sep 2011

U.S. smoking rates on slow decline: CDC report

Roughly 45 million adult Americans smoke and this is much lesser than the figures a few years back. Even those who still smoke have cut back on the number of cigarettes they smoke, but the rate of decline has begun to slow, U.S. health experts said on Tuesday. Smoking and exposure to secondhand smoke is the leading cause of preventable death and disease in the United States, killing an estimated 443,000 Americans each year.

6 Sep 2011

FDA stalls the blood-thinner Xarelto’s approval citing inadequate evidence

The Food and Drug Administration (FDA) said in a staff report released today that “there is insufficient information about the drug to determine whether it is safe for use with its proposed labeling.” Their report questions its safety and effectiveness, saying a new study is needed.

6 Sep 2011

Discovery of a key protein’s role in cell clearance could impact future treatments of autoimmune diseases, obesity and atherosclerosis

The healthy human body is extremely efficient at cleaning house. Every day, we purge 100 to 200 billion dead or dying cells – a process called cell clearance, which is fundamental in our ability to maintain a healthy physiological balance and prevent a number of chronic diseases. Professional cleaning cells, called phagocytes, are responsible for ridding the body of dead, or ‘apoptotic,’ cells.

6 Sep 2011

Chocolate protects heart but stirs debate on intake

A new study shows that chocolates are beneficial for heart health. The study published in the British Medical Journal and presented at the European Cardiology Society's annual congress in Paris analyzed data from seven studies involving 114,009 adults, ages 25 to 93, and including information on their diets and occurrences of cardiovascular disease over periods from eight to 16 years.

6 Sep 2011