Heart Disease News and Research

Latest Heart Disease News and Research

DES: friend or foe?

The current FDA approved stents (CYPHER and TAXUS) have been associated with late stent thrombosis (LST) (>30days following implantation) however, the mechanisms predictive of LST are poorly understood. Pathologic studies are one of the best methods for detailed analysis of morphologic changes that occur after placement of Drug Eluting Stents to determine the causes of LST.

3 Sep 2007

The burden of diabetes in heart disease in Europe

Diabetes is becoming one of the major health problems in the European and US populations. It is frequently associated with overweight, hypertension and high serum cholesterol levels, representing a dangerous combination of risk factors for the development of heart and vascular diseases.

2 Sep 2007

Risk stratification in acute heart failure

Hospitalization for acute heart failure is the most relevant burden for the health systems in both Europe and North America. Despite its dramatic impact on patient survival, quality of life and health costs, relatively few studies have been conducted in patients with this clinical condition in order to identify effective therapeutic strategies able to improve not only symptoms but also patient survival.

2 Sep 2007

Long term follow up of additional Swedish registry data does not indicate an increased

Four years of follow up including additional patients in the Swedish Coronary angiography and angioplasty registry (SCAAR) does no longer indicate any increased mortality in patients treated with drug eluting stents compared to patients treated with bare metal stents.

2 Sep 2007

Blood pressure drugs cut death rate in diabetes

The largest-ever study of treatments for diabetes has shown that a fixed combination of two blood pressure lowering drugs reduces the risk of death, as well as the risks of heart and kidney disease. Results from the ADVANCE (Action in Diabetes and Vascular Disease) Study were presented today at the European Society of Cardiology Congress 2007 in Vienna.

2 Sep 2007

The first clinically available oral direct renin inhibitor shows promise in heart failure

Drugs that block a hormonal cascade, known as the renin-angiotensin-aldosterone system (RAAS), help patients with heart failure. Direct renin inhibitors (DRIs) block the RAAS at its first and rate-limiting step.

2 Sep 2007

Clinical reality of coronary prevention in Europe : A comparison

Dr Kornelia Kotseva, Consultant Cardiologist and the Project Manager for the EUROASPIRE III survey commented "despite the increase in prophylactic drug therapy, the majority of coronary patients in Europe have still not achieved the blood pressure target and two out of five are not achieving the total cholesterol goal".

2 Sep 2007

Efficacy of non-invasive ventilation in patients with acute cardiogenic pulmonary oede

Acute cardiogenic pulmonary oedema, or "fluid on the lung", is a common, extremely distressing and often fatal condition that is a major consumer of health care resources. The aim of the 3CPO trial was to establish whether high-pressure oxygen, given by a simple facemask, could help reduce the death rate in patients with this condition.

2 Sep 2007

Are there gender differences in management modalities?

There are major differences in the risk profile and characteristics of female patients treated for acute heart failure. Female patients are underrepresented in management trials on Heart Failure. According to data from the Euro Heart Survey on acute Heart Failure 2004-2005 in Europe, however, medical treatment has improved.

2 Sep 2007

Survey to evaluate arrhythmia rate in so-called high-risk MI patients

Sudden cardiac death is the leading cause of mortality in European and North-American countries. Studies have been attempting to identify the right population of patients at high risk of Sudden Cardiac Death ever since the introduction of the Implantable Cardioverter Defibrillators (ICD).

2 Sep 2007

Does physical activity provide a molecular key to longevity?

Fitness and physical exercise are among the most neglected means to improve prognosis. They are the healthiest cardiovascular intervention. Even cardiologists focus on pharmacological treatment and evaluate classical risk factors without asking about daily exercise or objective measures of physical capacity. It is surprising considering the strong data that underscores the survival benefit of regular exercise training.

2 Sep 2007

Many city convenience stores lacking health foods

A survey of convenience stores in the south west section of Rochester has revealed that 95% offer little or no healthy foods.

30 Aug 2007

Triage guidelines for emergency heart patients studied

Two new studies led by researchers at the University of Iowa and the Department of Veterans Affairs Iowa City Health Care System provide reassuring findings for patients evaluated in the emergency room for possible acute coronary syndrome (ACS) and the physicians who treat them.

30 Aug 2007

Small animal imaging facility is big boon to research

When powerful magnets line up the body's protons before radiofrequency waves can grab their attention away, it's called spin physics.

30 Aug 2007

New evidence links discontinuation of statin therapy to increased death rates in stroke survivors

Patients who stop taking cholesterol-lowering drugs within a year of surviving a stroke had a two-fold increased risk of death, researchers reported in Stroke: Journal of the American Heart Association.

30 Aug 2007

Discovery of novel cause of iron overload in patients with thalassemia

According to the study, thalassemia patients overproduce a protein called GDF15, which suppresses the production of a liver protein, hepcidin, which in turn leads to an increase in the uptake of dietary iron in the gut.

30 Aug 2007

Inhaling nitric oxide helps transplant success

Administering inhaled nitric oxide (NO) during surgery helps protect liver transplant patients from organ failure, according to a new study from researchers at the University of Alabama at Birmingham (UAB).

30 Aug 2007

FDA approves Somatuline Depot to treat acromegaly

The U.S. Food and Drug Administration has approved Somatuline Depot (lanreotide acetate injection) for the treatment of acromegaly, a rare and potentially life threatening disease in adults caused by abnormal secretion of growth hormone (GH), commonly from a benign tumor located in the pituitary gland located in the brain.

30 Aug 2007

COPD can no longer be judged as only a disease of the lungs

Chronic Obstructive Pulmonary Disease (COPD) can no longer be judged as only a disease of the lungs, say authors of a Viewpoint in this week's COPD special edition of The Lancet.

30 Aug 2007

Prevalence of algatoxin in the marine environment appears to be increasing

If ingested, for example in seafood, these toxins can lead to discomfort or even illness. The algatoxin yessotoxin (YTX), which is found in both mussels and scallops in Norway, may be a potential disease risk factor in the consumption of seafood. "We don't know the long-term effects of YTX on people", says Monica Suarez Korsnes of the Norwegian School of Veterinary Science (NVH).

30 Aug 2007