Immunology News and Research

Latest Immunology News and Research

Study highlights the need for caution while using CRISPR-based gene therapies

A comprehensive study - conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups - has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer.

11 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Scientists at Oxford University have identified the gene responsible for doubling the risk of respiratory failure from COVID-19.

9 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis. ICI-induced myocarditis represents a new clinical syndrome because of the novelty and considerable usage of ICIs.

7 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which travel from the bone marrow.

6 Nov 2021

Key link between chronic stress and cancer discovered

Stress can have a significant negative effect on health, but our understanding of how stress impacts the development and progression of cancer is just beginning.

6 Nov 2021

Cross-reactive immunity against coronaviruses

Researchers review the heterologous immunity to coronaviruses and the extent of immune cross-reactivity against SARS-CoV-2.

3 Nov 2021

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

A new study aimed to identify several potent neutralizing RBD-directed and NTD-directed mAbs that used a nanoparticle displaying the S glycoprotein to capture SARS-CoV-2-specific B cells.

2 Nov 2021

New genetic epidemiology tool provides detailed information about viruses, coinfections

With mask wearing and social distancing on the decline and the cold and flu season upon us, researchers have developed a viral panel that enables the simultaneous testing for SARS-CoV-2 along with numerous common respiratory viruses, that tells us whether other viruses also are at play in patients hard hit by COVID.

1 Nov 2021

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences.

1 Nov 2021

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

Research reveals how gut macrophages respond to prior infection by shielding enteric neurons

A simple stomach bug could do a lot of damage. There are 100 million neurons scattered along the gastrointestinal tract - directly in the line of fire - that can be stamped out by gut infections, potentially leading to long-term GI disease.

30 Oct 2021

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

A decades-long friendship and a shared passion for basic science has inspired a $15 million gift to the Division of Biology & Biomedical Sciences (DBBS) at Washington University in St. Louis to fund undergraduate programs and graduate student fellowships in the life sciences.

30 Oct 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Scientists develop new approach to combat treatment-resistant melanoma

Researchers from the Centenary Institute have developed a new approach to fighting melanomas that fail to respond – or are resistant – to standard treatments. The deadliest form of skin cancer, melanoma is responsible for more than 1,700 deaths each year in Australia.

30 Oct 2021

Study discovers inflammatory mediator critically involved in bacterial pneumonia

Researchers at Karolinska Institutet in Sweden report that a recently discovered inflammatory mediator, interleukin-26, appears to have an important role in pneumonia and contribute to the killing of bacteria.

29 Oct 2021

Immunology News and Research

Latest Immunology News and Research

Study highlights the need for caution while using CRISPR-based gene therapies

New discovery could lead to the creation of a pan-coronaviruses vaccine

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Key link between chronic stress and cancer discovered

Cross-reactive immunity against coronaviruses

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

New genetic epidemiology tool provides detailed information about viruses, coinfections

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

Research reveals how gut macrophages respond to prior infection by shielding enteric neurons

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

Researchers decipher when and why T cells become non-responsive to immunotherapy

Scientists develop new approach to combat treatment-resistant melanoma

Study discovers inflammatory mediator critically involved in bacterial pneumonia

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