Immunology News and Research

Latest Immunology News and Research

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature

A Loyola University Chicago study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a similar ability to cause damage when they invade brain cells.

23 May 2017

Scientists report promising approach to combat influenza and improve survival

The influenza virus turns infected lung cells into factories that churn out thousands of copies of the virus to spread the infection. St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu-infected mice.

23 May 2017

Study describes novel T cell population that recognizes and kills tumor cells

Scientists at the University of Basel in Switzerland have, for the first time, described a new T cell population that can recognize and kill tumor cells. The open access journal eLife has published the results.

23 May 2017

Experimental treatment tempers HLH, MS symptoms in mouse models, study shows

Immune diseases like multiple sclerosis and hemophagocytic lymphohistiocytosis unleash destructive waves of inflammation on the body, causing death or a lifetime of illness and physical impairment.

23 May 2017

Cancer drug may help treat food allergies

A cancer drug for patients with certain types of leukemia and lymphoma can also prevent reactions to some of the most common airborne allergies, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.

22 May 2017

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Scientists have shown how diesel fumes trigger respiratory reflexes which could potentially worsen underlying conditions, such as asthma.

22 May 2017

New findings could lead to first broadly effective ebolavirus therapies and vaccines

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.

19 May 2017

New clinical trial offers hope for patients with hard-to-treat cancer caused by asbestos

Patients with a hard-to-treat type of cancer are being given new hope in a ground-breaking clinical trial. Researchers at the University of Southampton and the University of Leicester are trialing a drug that could boost the body's immune system to fight off mesothelioma, which can be caused by asbestos.

19 May 2017

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Adding the injectable drug mepolizumab to standard treatment for eosinophilic granulomatosis with polyangiitis (EGPA), a rare immunologic disease, significantly improved clinical outcomes among participants in an advanced clinical trial, scientists report.

18 May 2017

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus.

18 May 2017

Researchers develop new imaging technique to ensure complete removal of tumor during surgery

Of the quarter-million women diagnosed with breast cancer every year in the United States, about 180,000 undergo surgery to remove the cancerous tissue while preserving as much healthy breast tissue as possible.

18 May 2017

Recovery from bacterial pneumonia changes the infected lung cells, study shows

When people develop a respiratory infection, recovery from their illness leaves behind an immunological memory that influences how they will respond to later infections.

17 May 2017

Researchers develop new strategy that can revolutionize HIV vaccine design

Vaccines are an essential tool for preventing and treating serious infectious diseases such as polio, chicken pox and measles. But so far it has not been possible to develop vaccines capable of contributing to the treatment and prevention of chronic infectious diseases such as HIV and hepatitis C.

17 May 2017

Scientists identify gene linked to incurable bowel disorders

A key gene that helps to explain an underlying cause of incurable bowel disorders such as Crohn's disease has been identified by scientists.

17 May 2017

New research could be first step toward drug to treat Zika infections

New research led by Alexey Terskikh, Ph.D., associate professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Alex Strongin, Ph.D., professor at SBP, could be a first step toward a drug to treat Zika infections. Publishing in Antiviral Research, the scientific team discovered a compound that prevents the virus from spreading.

16 May 2017

Scientists develop world's first smartphone app to collect large data for people with MS

What if a single smartphone app could help solve the enigma of multiple sclerosis and move new treatments ahead at lightning speed? That was the bold idea that led Keck Medicine of USC neurologist Daniel Pelletier, MD, professor of neurology at the Keck School of Medicine of USC and division chief of the Neuro-Immunology and USC Multiple Sclerosis Center, to develop myMS, the world's first smartphone app capable of collecting large amounts of clinical, imaging and genetic data for people with MS. Enrollment is now underway for a pilot study of the app.

16 May 2017

Scientists discover simple way to use light for steering killer immune cells toward tumors

The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors.

15 May 2017

Scientists uncover potential strategy to shock and kill HIV virus

Scientists at the Gladstone Institutes discovered that an enzyme called SMYD2 could be a new therapeutic target for flushing out the HIV that hides in infected individuals. Overcoming this latent virus remains the most significant obstacle to a cure.

15 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Immunology News and Research

Latest Immunology News and Research

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature

Scientists report promising approach to combat influenza and improve survival

Study describes novel T cell population that recognizes and kills tumor cells

Experimental treatment tempers HLH, MS symptoms in mouse models, study shows

Cancer drug may help treat food allergies

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

New findings could lead to first broadly effective ebolavirus therapies and vaccines

New clinical trial offers hope for patients with hard-to-treat cancer caused by asbestos

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

Researchers develop new imaging technique to ensure complete removal of tumor during surgery

Recovery from bacterial pneumonia changes the infected lung cells, study shows

Researchers develop new strategy that can revolutionize HIV vaccine design

Scientists identify gene linked to incurable bowel disorders

New research could be first step toward drug to treat Zika infections

Scientists develop world's first smartphone app to collect large data for people with MS

Scientists discover simple way to use light for steering killer immune cells toward tumors

Scientists uncover potential strategy to shock and kill HIV virus

Study findings could pave way for better drugs to fight against parasitic infections

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