Immunology News and Research

Latest Immunology News and Research

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

10 May 2017

Researchers uncover structure of embryo-protecting protein

Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.

10 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Researchers discover that microRNA can prevent excessive intestinal inflammation

An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine.

9 May 2017

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Researchers have identified a metabolite 'signature' that can accurately distinguish typhoid from other fever-inducing tropical diseases using patient blood samples.

9 May 2017

Dendritic cells develop from specialized progenitors, research shows

Dendritic cells are gatekeepers of Immunity and are crucial for the detection and initiation of Immunity against pathogens and foreign substances. Up to now dendritic cell subtypes were thought to develop from one common progenitor.

5 May 2017

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Immunotherapy, which has achieved remarkable results in late-stage lung cancer patients, can also hold great hope for newly diagnosed patients, cutting the deadly disease off before it has the chance to take hold and offering a potential cure, according to a new Mount Sinai study published today in Cell.

4 May 2017

Scientists identify how key skin barrier protein drives development of eczema

Scientists have uncovered evidence that a deficiency in the skin's barrier is key to triggering eczema. The team at Newcastle University, in collaboration with scientists at Stiefel, a GSK company, have identified how a key skin barrier protein called filaggrin impacts on other proteins and pathways in the skin, which in turn drive the development of eczema.

4 May 2017

Phthalate exposure linked to increased risk of allergies among children

Phthalates, which are used as plasticizers in plastics, can considerably increase the risk of allergies among children.

3 May 2017

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Shire plc and Parion Sciences, Inc. have announced they have entered into an agreement granting Shire exclusive worldwide rights to develop and commercialize P-321. Shire will lead development of P-321, an investigational epithelial sodium channel (ENaC) inhibitor for the potential treatment of dry eye disease in adults, with the opportunity for Parion to co-fund.

3 May 2017

New study shows that gene editing technology can shut down HIV-1 replication in animals

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecular Therapy, scientists at the Lewis Katz School of Medicine at Temple University and the University of Pittsburgh show that they can excise HIV DNA from the genomes of living animals to eliminate further infection.

2 May 2017

Different doses of resistance exercises could aid recovery from infection, injury

Having your healthcare professional prescribe you a dose of bench presses to ward off an infection or help heal an injury may sound like shonky healthcare but could actually be the advice of the near future, according to Griffith University scientists.

29 Apr 2017

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly $1.4 million in funding from the National Library of Medicine of the U.S. National Institutes of Health and more than $1 million from Penn State.

28 Apr 2017

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a team of researchers at the Medical University of South Carolina and the Dartmouth-Hitchcock Norris Cotton Cancer Center In the April 14, 2017, Science Immunology.

28 Apr 2017

Pregnancy does not have adverse effect on prognosis of melanoma in expectant mothers

Expectant mothers need not be concerned that they are more prone to develop melanoma, or will have a worse prognosis if they do get this serious skin cancer, than women who are not pregnant, according to study results published online as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.

27 Apr 2017

Unique microscope reveals clues to destructive autoimmune disease

Using a unique microscope capable of illuminating living cell structures in great detail, researchers at the University of Colorado Anschutz Medical Campus have found clues into how a destructive autoimmune disease works, setting the stage for more discoveries in the future.

26 Apr 2017

Neurobiologists use skin stem cells to generate new microglia

Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.

25 Apr 2017

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.

24 Apr 2017

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

21 Apr 2017

Immunology News and Research

Latest Immunology News and Research

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Researchers uncover structure of embryo-protecting protein

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Researchers discover that microRNA can prevent excessive intestinal inflammation

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Dendritic cells develop from specialized progenitors, research shows

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Scientists identify how key skin barrier protein drives development of eczema

Phthalate exposure linked to increased risk of allergies among children

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

New study shows that gene editing technology can shut down HIV-1 replication in animals

Different doses of resistance exercises could aid recovery from infection, injury

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

Pregnancy does not have adverse effect on prognosis of melanoma in expectant mothers

Unique microscope reveals clues to destructive autoimmune disease

Neurobiologists use skin stem cells to generate new microglia

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

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