Immunology News and Research

Latest Immunology News and Research

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

Purdue University-led researchers determine structure of Zika virus

A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines.

1 Apr 2016

Study points to possible new genetic risk factor for celiac disease

Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing celiac disease in people with celiac disease risk genes.

1 Apr 2016

Baricitinib drug shows significant success in treatment of rheumatoid arthritis

In a clinical phase-3-study, an international research cooperation of MedUni Vienna and Stanford University has achieved significant success with the drug Baricitinib for the treatment of rheumatoid arthritis. The test persons exhibited significantly less symptoms of the disorder. The results are now published in the top scientific journal "New England Journal of Medicine".

31 Mar 2016

Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

The risk in terms of the Olympics, especially for travelling populations remains low – with the notable exception of pregnant women.

31 Mar 2016

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

Researchers at the University of Georgia and Sanofi Pasteur, the vaccines division of Sanofi, announced today the development of a vaccine that protects against multiple strains of both seasonal and pandemic H1N1 influenza in mouse models.

30 Mar 2016

Researchers clarify potential transmissibility of Alzheimer's disease

MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer's disease. Although the protein associated with Alzheimer's disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer's disease. The affected persons develop no clinical symptoms of the disease.

29 Mar 2016

KAIST researchers develop bio-medical imaging tool to view, analyze live cells

Professor YongKeun Park of the Physics Department at the Korea Advanced Institute of Science and Technology and his research team have developed a powerful method for 3D imaging of live cells without staining. The researchers announced the launch of their new microscopic tool, the holotomography (HT)-1, to the global marketplace through a Korean start-up that Professor Park co-founded, TomoCube.

29 Mar 2016

Oral administration of cyclotide may improve symptoms of multiple sclerosis

MedUni Vienna has made a crucial development in the treatment of Multiple Sclerosis (MS): Together with his team and the research group led by Gernot Schabbauer, international partners from Australia, Germany and Sweden, Christian Gruber, Chief Researcher at the Center for Physiology and Pharmacology has demonstrated in an animal model that, following treatment with a specially synthesized plant peptide (cyclotide), there is no further progression of the usual clinical signs of multiple sclerosis.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

New drug regimens could significantly improve treatment for tuberculosis

Researchers from UCLA and Shanghai Jiao Tong University have made an important step toward a substantially faster and more effective treatment for tuberculosis, which infects some 10 million people and causes 1.5 million deaths each year.

29 Mar 2016

Engineered HIV vaccine protein may prevent HIV infection

Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and scientists are working to develop a vaccine capable of inducing such "broadly neutralizing" antibodies that can prevent HIV infection.

28 Mar 2016

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Infections with bacterium Clostridium difficile have rapidly become a significant medical problem in hospitals and long-term care facilities. The bacteria cause diarrhea and life-threatening inflammation of the colon by producing toxins that kill the endothelial cells that form the lining of the gut.

26 Mar 2016

Researchers develop rapid yet inexpensive test for TB

Although tuberculosis (TB) is commonly thought of as being a disease that mainly affects nineteenth century poets and Victor Hugo characters, it is still the second-most common cause of mortality from an infectious disease in the world, killing nearly three people every minute. Every March 24, on World TB Day, the global health community recognizes the work of Robert Koch, who announced on that date in 1882 his discovery of Mycobacterium tuberculosis, the bacteria that causes TB.

25 Mar 2016

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated.

24 Mar 2016

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Distinguished Professor Jae Jung, PhD, chair of the Department of Molecular Microbiology & Immunology and the director of the University of Southern California Institute for Emerging Pathogens and Immune Diseases at the Keck School of Medicine of USC, is among this year's recipients of the National Cancer Institute Outstanding Investigator Award.

23 Mar 2016

Metabolite in gut microbiome could improve outcomes after bone marrow transplant

Could playing better defense make bone marrow transplants more successful? With this question in mind, researchers began looking at whether the trillions of little bugs and bacteria living in our gastrointestinal tract could be the key to playing defense.

22 Mar 2016

Researchers use DNA sequencing technology to identify gene variants that affect susceptibility to SLE

Demonstrating the potential of precision medicine, an international study based at UT Southwestern Medical Center used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to systemic lupus erythematosus (SLE).

21 Mar 2016

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Cancer cells have the ability to grow in an acidic tumor environment that is detrimental to other cells, including immune cells. In a Cancer Research cover article published this week, Moffitt Cancer Center reported that neutralizing the acidic tumor environment increases the efficacy of several immune-targeting cancer therapies.

19 Mar 2016

Newly developed computer models can simulate stem cell transplant recovery

Scientists at Virginia Commonwealth University have developed computer models that can simulate the recovery of the immune system in patients undergoing stem cell transplants.

18 Mar 2016

Immunology News and Research

Latest Immunology News and Research

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Purdue University-led researchers determine structure of Zika virus

Study points to possible new genetic risk factor for celiac disease

Baricitinib drug shows significant success in treatment of rheumatoid arthritis

Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

Researchers clarify potential transmissibility of Alzheimer's disease

KAIST researchers develop bio-medical imaging tool to view, analyze live cells

Oral administration of cyclotide may improve symptoms of multiple sclerosis

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

New drug regimens could significantly improve treatment for tuberculosis

Engineered HIV vaccine protein may prevent HIV infection

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Researchers develop rapid yet inexpensive test for TB

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Metabolite in gut microbiome could improve outcomes after bone marrow transplant

Researchers use DNA sequencing technology to identify gene variants that affect susceptibility to SLE

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Newly developed computer models can simulate stem cell transplant recovery

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