Immunology News and Research

Latest Immunology News and Research

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

Two new studies by cancer scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggest new approaches for treating cancer by inhibiting overactive cancer-promoting genes and by enhancing the activity of sluggish tumor-suppressor genes.

7 Oct 2015

NIH researchers discover why certain immune responses can be harmful to the brain

National Institutes of Health scientists studying inflammation of the brain have discovered why certain immune responses, which typically help cells recognize and fight viral and bacterial infections, can sometimes be harmful to the brain. Many brain disorders involve the death of neurons, or nerve cells, but how these neurons die is not well understood.

7 Oct 2015

Finding could lead to potential new treatment for patients with autoimmune diseases

Antibodies protect the body against diseases - but can also harm their own organism if the reactions are misdirected. Researchers from the University of Zurich have now discovered that a particular sugar in the antibodies determines whether one of the body's own cells is destroyed or not. This result could lead to new treatment possibilities for patients with autoimmune diseases.

6 Oct 2015

FDA accepts Sandoz regulatory submission for a proposed biosimilar etanercept

Sandoz, a Novartis company and the global leader in biosimilars, announced today that the US Food and Drug Administration (FDA) has accepted its Biologics License Application (BLA) under the 351 (k) pathway for its proposed biosimilar to Amgen’s US-licensed Enbrel (etanercept) - a tumor necrosis factor alpha (TNF-α) inhibitor

5 Oct 2015

Four types of gut bacteria can protect infants from asthma

New research by scientists at UBC and BC Children's Hospital finds that infants can be protected from getting asthma if they acquire four types of gut bacteria by three months of age.

1 Oct 2015

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

David Griggs, Ph.D., director of biology at Saint Louis University's Center for World Health & Medicine, has received a $1 million R01 grant from the National Institutes of Health to investigate the development of what could be a new class of drugs to treat bone diseases.

30 Sep 2015

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on the study of one case with aggressive variant of breast cancer - invasive micropapillary carcinoma by researchers from Tomsk State University, Tomsk Cancer Research Institute, and Institute of Medical Genetics.

30 Sep 2015

Duke Medicine scientists use transparent fish to show how Cryptococcal meningitis takes over the brain

Scientists at Duke Medicine are using transparent fish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,000 people worldwide each year.

29 Sep 2015

Unique molecule can bind HIV-infected cells to killer T cells

A unique molecule developed at Duke Medicine, the University of North Carolina at Chapel Hill and MacroGenics, Inc., is able to bind HIV-infected cells to the immune system's killer T cells. It could become a key part of a shock-and-kill strategy being developed in the hope of one day clearing HIV infection.

29 Sep 2015

Scientists develop new molecular toolkit to investigate protein assemblies in human disease

A photograph may reveal how something looks, but direct observation can divulge how the objects behave. The difference can mean life or death, especially when it comes to fighting human disease.

29 Sep 2015

New study broadens understanding of how the immune system responds to flu virus

A new study of influenza infection in an animal model broadens understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described, engaging a broader array of biological pathways. The researchers say their findings may offer key insights for designing more effective vaccines in general.

29 Sep 2015

Specialized proteins can inhibit HIV

There is little doubt that the Human Immunodeficiency Virus, or HIV, is devastating. More than 1.2 million people in the United States are living with HIV and more than 47,000 people are diagnosed annually. Now, University of Missouri researchers have made a discovery in how specialized proteins can inhibit the virus, opening the door for progress in the fight against HIV and for the production of advanced therapeutics to combat the disease.

29 Sep 2015

Increasing availability of genetic tests for at-risk cancer patients

Mutations in the BRCA 1 and BRCA 2 genes are very likely to lead to a form of cancer in people who have them. These mutations can be detected using a genetic test. The introduction of a new drug has improved treatment options and this, coupled with increased awareness and improved access, increased the number of genetic tests carried out at the MedUni Vienna last year by a factor of five.

28 Sep 2015

Nivolumab drug significantly prolongs survival in advanced kidney cancer patients

The targeted drug nivolumab significantly prolongs survival in patients with advanced kidney cancer, whose disease has progressed after their first treatment, according to results to be presented at the 2015 European Cancer Congress today (Saturday) and published simultaneously in the New England Journal of Medicine.

26 Sep 2015

Immune checkpoint inhibitor increases survival in patients with advanced renal cell carcinoma

For the first time, an immune checkpoint inhibitor has been proven to increase survival among patients with advanced renal cell carcinoma (RCC), a patient population for whom treatment options are currently limited.

26 Sep 2015

H7N9 influenza vaccine failure may be due to immune camouflage, study reveals

The avian influenza A (H7N9) virus has been a major concern since the first outbreak in China in 2013. Due to its high rate of lethality and pandemic potential, H7N9 vaccine development has become a priority for public health officials. However, candidate vaccines have failed to elicit the strong immune responses necessary to protect from infection.

25 Sep 2015

AbbVie reports positive results from ABT-494 Phase 2 clinical trials in patients with rheumatoid arthritis

AbbVie, a global biopharmaceutical company, today announced results from two Phase 2 clinical trials evaluating its investigational selective JAK1 inhibitor, ABT-494, in patients with inadequate response to either methotrexate or TNF inhibitors.

25 Sep 2015

Researchers develop new blood test to diagnose coeliac disease

Diagnosis of coeliac disease requires a tissue sample from the small intestine, which can be extremely unpleasant. Researchers at the Faculty of Medicine have developed a blood test which provides a rapid, painless answer.

25 Sep 2015

Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

Secondhand smoke exposure doubles risk of hospitalization for kids with asthma

The risk for hospitalization doubles for kids with asthma who are exposed to secondhand smoke, according to a study led by Mayo Clinic Children's Research Center. "The results of this review serve as a reminder to parents of just how dangerous it is to expose their children to secondhand smoke," says Avni Joshi, M.D., senior author and pediatric allergist and immunologist at Mayo Clinic Children's Center.

24 Sep 2015

Immunology News and Research

Latest Immunology News and Research

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

NIH researchers discover why certain immune responses can be harmful to the brain

Finding could lead to potential new treatment for patients with autoimmune diseases

FDA accepts Sandoz regulatory submission for a proposed biosimilar etanercept

Four types of gut bacteria can protect infants from asthma

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Duke Medicine scientists use transparent fish to show how Cryptococcal meningitis takes over the brain

Unique molecule can bind HIV-infected cells to killer T cells

Scientists develop new molecular toolkit to investigate protein assemblies in human disease

New study broadens understanding of how the immune system responds to flu virus

Specialized proteins can inhibit HIV

Increasing availability of genetic tests for at-risk cancer patients

Nivolumab drug significantly prolongs survival in advanced kidney cancer patients

Immune checkpoint inhibitor increases survival in patients with advanced renal cell carcinoma

H7N9 influenza vaccine failure may be due to immune camouflage, study reveals

AbbVie reports positive results from ABT-494 Phase 2 clinical trials in patients with rheumatoid arthritis

Researchers develop new blood test to diagnose coeliac disease

Stanford researchers successfully defeat C. difficile bacteria

Secondhand smoke exposure doubles risk of hospitalization for kids with asthma

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