Immunotherapy News and Research

Latest Immunotherapy News and Research

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

Biological anti-tumor mechanism can provide long-term immune response against tumors

Blocking a newly identified "immune memory checkpoint" in immune cells could improve immunotherapy and help prevent cancers from recurring, according to new findings in mice and human samples by researchers at the UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine.

15 Jul 2020

MD Anderson and Sanofi collaborate to accelerate development of innovative cancer therapies

The University of Texas MD Anderson Cancer Center and Sanofi today announced a five-year strategic collaboration to accelerate the development of investigational treatments, including targeted and immune therapies, for patients with cancer.

14 Jul 2020

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) - a rare and hard-to-treat cancer.

14 Jul 2020

International research collaboration to investigate the role of immune system in health

An international research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

13 Jul 2020

Drug associated with lower mortality in mechanically ventilated COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

13 Jul 2020

Novel drug could enable the immune system to attack ovarian cancer

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Researchers develop new approach to assess changes in tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response. The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

12 Jul 2020

Promising new approach uses natural killer cells to treat glioblastomas

Glioblastomas are the most common malignant brain tumors in adults. Treatment options are extremely limited and usually not effective, leading to death for most patients within 12-18 months of diagnosis.

9 Jul 2020

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

Sheba Medical Center at Tel HaShomer and Immunicom, Inc. are initiating a ground-breaking clinical trial to evaluate the clinical effectiveness of the Immunicom LW-02 plasma filtration device as a monotherapy and in combination with an anti-PD-1 immune checkpoint inhibitor.

9 Jul 2020

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

Immunotherapy News and Research

Latest Immunotherapy News and Research

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Promising new CAR T cell therapy results in exceptional patient recovery

Study identifies possible factors to predict severe toxicities in CAR T patients

Biological anti-tumor mechanism can provide long-term immune response against tumors

MD Anderson and Sanofi collaborate to accelerate development of innovative cancer therapies

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

International research collaboration to investigate the role of immune system in health

Drug associated with lower mortality in mechanically ventilated COVID-19 patients

Novel drug could enable the immune system to attack ovarian cancer

Researchers develop new approach to assess changes in tumor microenvironment

Promising new approach uses natural killer cells to treat glioblastomas

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Breast cancer cells can reprogram natural killer cells to aid in metastasis

PRMT5 inhibitors can help treat advanced melanoma

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

Fred Hutch joins new clinical trials network to fight COVID-19

Scientists introduce a new approach for immunological tumor treatment

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

Scientists engineer natural killer cells that target tumors and their immunosuppressive allies

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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