Immunotherapy News and Research

Latest Immunotherapy News and Research

Cancer clusters' resistance to natural killer cell immunosurveillance favors metastasis

Scientific evidence suggests that cancer can metastasize to other organs when either a single cell or a cluster of cells detaches from the original tumor and travels through the blood to another location, where it grows into a new tumor.

1 Jun 2020

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

A new type of immunotherapy treatment for metastatic non-small cell lung cancer (NSCLC) is being tested by Missak Haigentz, Jr., MD, medical director of hematology and oncology for Atlantic Health System.

30 May 2020

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of patients with a specific subtype of advanced bowel cancer, when compared with chemotherapy.

30 May 2020

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

A harmonization of 'big data' in examining long-term outcomes with contemporary treatment for pediatric and adult Hodgkin lymphoma patients is yielding a new approach to inform future clinical trial design and enhance clinical decision-making.

30 May 2020

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs.

30 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

New tool may predict best treatment for multiple myeloma

In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question has become what cocktail and sequence is best?

29 May 2020

Radiation and surgery do not prolong survival in newly diagnosed metastatic breast cancer

Up to now, women who present with a new diagnosis of breast cancer that is already in an advanced stage (stage IV) face an unanswered question about whether surgery and radiation to the tumor in the breast (local therapy) will prolong survival compared to the traditional treatment of systemic treatment alone.

29 May 2020

Characterizing immune cells in malignant brain tumors

It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary.

28 May 2020

New drug combinations could help overcome genetic immunotherapy resistance

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

28 May 2020

Researchers develop promising immunotherapy treatment for glioblastoma

Researchers of McMaster University and the University of Toronto have developed a promising immunotherapy treatment for a deadly form of adult brain cancer called glioblastoma.

27 May 2020

Novel immunotherapy targeting myeloid immune cells reduces tumor growth

Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions.

27 May 2020

A promising method for treating triple-negative breast cancer

Researchers at the University of Queensland may have found a way to improve treatment of triple-negative breast cancer.

27 May 2020

Inherited genetic variations can alter progression of melanoma, indicates study

Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive this potentially devastating turn of events.

26 May 2020

Platinum-based chemotherapy may improve outcomes for some metastatic pancreatic cancer patients

Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations.

22 May 2020

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Two novel biomarkers have been found to correlate with improved outcomes with immunotherapy in metastatic breast cancer and may help to identify the patients most likely to benefit from this treatment, according to exploratory studies reported at the ESMO Breast Cancer Virtual Meeting 2020.

22 May 2020

New clinical trial to test treatment that targets overactive immune response to COVID-19

For some COVID-19 patients, the body's immune response may be as destructive as the virus that causes the disease.

22 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

Scientists develop novel flow cytometry technique to quantify protein production in T-cells

A team of scientists from Hollings Cancer Center at the Medical University of South Carolina (MUSC) has developed a novel flow cytometry technique that can, for the first-time, quantify protein production in T-cells.

20 May 2020

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Immunotherapy News and Research

Latest Immunotherapy News and Research

Cancer clusters' resistance to natural killer cell immunosurveillance favors metastasis

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

New tool may predict best treatment for multiple myeloma

Radiation and surgery do not prolong survival in newly diagnosed metastatic breast cancer

Characterizing immune cells in malignant brain tumors

New drug combinations could help overcome genetic immunotherapy resistance

Researchers develop promising immunotherapy treatment for glioblastoma

Novel immunotherapy targeting myeloid immune cells reduces tumor growth

A promising method for treating triple-negative breast cancer

Inherited genetic variations can alter progression of melanoma, indicates study

Platinum-based chemotherapy may improve outcomes for some metastatic pancreatic cancer patients

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

New clinical trial to test treatment that targets overactive immune response to COVID-19

FDA approves IND application by Octapharma USA for severe COVID-19 patients

Scientists develop novel flow cytometry technique to quantify protein production in T-cells

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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