Influenza

Influenza (the flu) is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness, and at times can lead to death. The best way to prevent the flu is by getting a flu vaccination each year. Every year in the United States, on average 5% to 20% of the population gets the flu; more than 200,000 people are hospitalized from flu complications, and; about 36,000 people die from flu-related causes. Some people, such as older people, young children, and people with certain health conditions, are at high risk for serious flu complications.

Types of Influenza

Influenza is caused by three types of RNA viruses called influenza types A, B and C, which all belong to the family Orthomyxoviridae.

Influenza Immunization

Influenza Epidemiology

Influenza Prognosis

Influenza Symptoms

Influenza Treatments

Influenza Pandemics

Influenza Research

Influenza Infection in Animals

Should I get the Flu Shot?

Latest Influenza News and Research

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

Common anti-inflammatory drugs may aid virus spread

New research shows an unintended and unfortunate side effect of common drugs. They can simply help viruses spread.

19 May 2025

Socioeconomic gaps persist in COVID-19 vaccination among older Swedes

The spring COVID-19 vaccination program in Sweden is in its final stages in several parts of the country. The program has encompassed free booster doses for those at increased risk of serious illness, including the very oldest members of society.

16 May 2025

Breakthrough bat organoid platform sheds light on behavior of zoonotic viruses

Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world's most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks.

15 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Failure to adopt covid suppression strategy led to avoidable deaths in the UK

Early in the covid-19 pandemic, the failure of UK government advisers to follow World Health Organization (WHO) advice and emerging evidence from East Asia that suppression could bring the virus under control quickly led to avoidable UK deaths, argues an expert in The BMJ today.

12 May 2025

New model reveals H5N1 is spreading undetected in US dairy herds

Researchers developed a nationwide model to simulate the spread of H5N1 in US dairy cattle, revealing significant under-reporting and predicting continued outbreaks into 2025. Targeted farm-level biosecurity and surveillance are urgently needed to contain the epidemic.

11 May 2025

New AI tool predicts viral mutations to help future-proof COVID vaccines

A novel AI-driven method helps scientists stay ahead of viral evolution by engineering synthetic spike proteins that anticipate future SARS-CoV-2 escape mutations, offering a powerful tool to test and strengthen next-generation vaccines.

11 May 2025

Virtual nurse shows promise in promoting vaccinations

Can a virtual nurse persuade people to get vaccinated? Scientists from SWPS University have proven that it is possible. Finding new forms of informing people about vaccinations is particularly important for public health while some question their validity.

10 May 2025

Nirsevimab slashes RSV hospitalizations in infants by 78% in real-world study

A Spanish study found that nirsevimab prophylaxis significantly reduced infant hospitalizations, ICU admissions, and severe symptoms linked to RSV and other respiratory viruses. Hospitalizations for RSV dropped by 78% following nirsevimab rollout in Madrid maternity wards.

8 May 2025

Monoclonal antibody protects mice from lethal influenza A doses

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows.

8 May 2025

Scientists enhance T cell immunity for more durable vaccines

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies.

7 May 2025

CEPI and University of Bergen collaborate on global vaccine mapping project

Supported by CEPI funding of up to $ 1.5 million over three years, researchers at Norway's University of Bergen will maintain an up-to-date overview of every vaccine candidate being developed around the globe for CEPI's priority pathogens as well as other emerging viral threats identified by CEPI.

5 May 2025

Trump team’s $500 million bet on old vaccine technology puzzles scientists

The Trump administration's unprecedented $500 million grant for a broadly protective flu shot has confounded vaccine and pandemic preparedness experts, who said the project was in early stages, relied on old technology, and was just one of more than 200 such efforts.

5 May 2025

Alabama can’t prosecute groups helping patients get abortions elsewhere, judge rules

Reproductive rights groups in Alabama wasted no time resuming their work after a federal judge ruled in early April that the state's attorney general can't prosecute — or threaten to prosecute — people or organizations who help Alabama residents seek an abortion by traveling to another state.

5 May 2025

New albumin-based vaccine shows promise for mucosal immunity

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines. Strategies to combat serious outbreaks of viral infections are particularly important.

2 May 2025

COVID-19 leaves longer-lasting symptoms than flu or pneumonia, study finds

A large U.S. cohort study found that post-acute symptoms after COVID-19 vary by initial disease severity, age, sex, and comorbidities. Compared to influenza and pneumonia, long COVID presented with distinct symptom patterns and longer-lasting effects.

1 May 2025

HHS and NIH announce the development of next-generation, universal vaccine platform

Colorized transmission electron micrograph of influenza A/H1N1 virus particles. The U.S. Department of Health and Human Services (HHS) and the National Institutes for Health (NIH) today announced the development of the next-generation, universal vaccine platform, Generation Gold Standard, using a beta-propiolactone (BPL)-inactivated, whole-virus platform.

1 May 2025

Urgent action needed to close gaps in global pandemic preparedness

The Global Virus Network (GVN) is highly concerned that the world is unprepared for the next pandemic and has not incorporated the lessons learned from COVID-19.

30 Apr 2025

Disrupted body clocks raise risk of early death, study finds

A large cohort study from China and the U.S. shows that Circadian Syndrome (CircS)—a cluster of metabolic and behavioral disruptions—is linked to higher all-cause and cause-specific mortality. The risk increases with the number of CircS components, especially among adults aged 40–60.

29 Apr 2025