Ketogenic Diet

The ketogenic diet is a high-fat, low-carbohydrate dietary approach that has gained significant attention for its clinical and therapeutic applications, particularly in epilepsy and metabolic health. This hub offers a comprehensive collection of articles that explore the scientific principles, mechanisms, efficacy, indications, contraindications, and potential side effects of the ketogenic diet. Whether you are a healthcare professional, patient, or someone interested in nutritional science, these resources offer up-to-date information on the diet’s history, diverse applications, safety considerations, and its impact on various health conditions. Explore the links below for detailed, evidence-based guidance on all aspects of the ketogenic diet.

What is the Ketogenic Diet?

The ketogenic diet is a special diet designed to help children with epilepsy that fails to respond adequately to routine anti-epileptic medications. A typical ketogenic diet is made up of the following...

The Healthy Eating Index: How Well Does Your Diet Score?

Ketogenic Diet and Epilepsy

Ketogenic Diet and Aging

How “Fad” Diets Affect the Gut Microbiota

Ketosis Controversy

Best and Worst Foods to Eat on the Ketogenic Diet

Paleo vs. Keto Diets

Ketogenic Diet Indications and Contra-Indications

Ketogenic Diet Types

History of the Ketogenic Diet

How Much Protein Do You Really Need Each Day to Stay Healthy?

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Latest Ketogenic Diet News and Research

Men lose more weight than women on the keto diet, new study reveals why

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex differences in hormones, metabolism, and fat distribution influence the effectiveness of the ketogenic diet for obesity.

22 Jun 2025

Back-to-basics, 'not fad' diets beat heart disease and diabetes

This review examines dietary interventions that can improve cardiometabolic health, highlighting the role of whole foods in reducing heart disease and diabetes.

4 Jun 2025

How soy and gut microbes alter cancer treatment results

Researchers have discovered that plant-derived phytochemicals and their gut microbiome metabolites control the effectiveness of PI3K inhibitors in cancer therapy. The study reveals that dietary components, especially soy compounds processed by gut bacteria, can alter drug metabolism and impact treatment outcomes.

2 Jun 2025

Which diet lowers blood pressure more: keto or Mediterranean?

A pilot study comparing a low-calorie, high-protein ketogenic diet and a Mediterranean diet in overweight and obese adults with elevated blood pressure found that both diets led to significant weight loss, improved body composition, and reduced blood pressure. Both dietary approaches were safe and well-tolerated, but the Mediterranean diet group showed a greater proportion of participants with healthy nocturnal blood pressure dipping.

26 May 2025

What really causes keto flu, and how can you prevent it?

A scoping review from the University of Bergen identifies a wide range of transient symptoms—collectively known as "keto flu"—that occur during the initiation of a ketogenic diet. The review explores their physiological basis and highlights strategies, such as MCTs and electrolyte supplementation, to ease the transition.

13 Apr 2025

High cholesterol may not signal heart disease risk in metabolically healthy people

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, in collaboration with researchers across multiple institutions, has published a new study that challenges the long-held belief that high cholesterol correlates and even directly causes coronary artery disease, or plaque buildup in the arteries in metabolically healthy individuals.

7 Apr 2025

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity speeds up biological aging at the molecular level, but this study finds that a very-low-calorie ketogenic diet (VLCKD) can significantly reverse this effect.

24 Mar 2025

Could a keto diet replace diabetes meds? New research explores the possibilities

A review published in Nutrients finds that ketogenic diets (KD) may offer superior benefits for weight loss, blood sugar control, and inflammation compared to other diets. Researchers also highlight potential mental health improvements but call for more clinical trials.

11 Mar 2025

UCLA Health launches study on ketogenic diet for bipolar disorder in youth

UCLA Health is set to begin a multi-site pilot study to explore whether a ketogenic diet, when combined with mood stabilizing medications, helps stabilize mood symptoms in teenagers and young adults who have bipolar disorder.

8 Feb 2025

How lifestyle-based interventions help manage PCOS

Studies indicate that lifestyle modifications can alleviate PCOS symptoms, improving insulin resistance and hormonal balance through diet and physical activity.

21 Jan 2025

Ketogenic diet leads in metabolic health improvements for diabetic patients

Study compares the effects of very-low-calorie ketogenic and Mediterranean diets on gut microbiota, metabolic health, and weight management in patients with newly diagnosed type 2 diabetes and obesity.

7 Jan 2025

Simple dietary supplement may provide new approach to boost CAR T cell cancer-fighting power

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

9 Dec 2024

Ketogenic diet linked to gut microbes and seizure reduction in epileptic children

The ketogenic diet's anti-seizure effects in children may be influenced by gut bacteria and metabolites, highlighting their role in epilepsy treatment.

7 Nov 2024

How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.

6 Nov 2024

Study links ketogenic diet to improved menstrual health

Increasing ketones in the blood through a keto diet or supplements may help put irregular menstrual cycles back on schedule or even restart a period that appears to have stalled for good, new research suggests.

30 Oct 2024

Simple dietary changes may help reduce migraine severity and medication use

Researchers reviewed the impact of various diets, including ketogenic and low-fat vegan, on reducing the frequency, intensity, and duration of migraine attacks, suggesting that dietary changes could complement traditional treatments.

13 Oct 2024

Ketogenic diet lowers mortality by 24% while maintaining heart health

Study confirms that adherence to a ketogenic diet reduces all-cause mortality risk by 24% without increasing cardiovascular mortality in a large US cohort. Findings support KD as a beneficial intervention for long-term health.

3 Oct 2024

Ketogenic diet restores menstrual cycles and boosts fertility in women with PCOS

A ketogenic diet restored menstrual cycles in all women with PCOS in a study, with over half of those desiring pregnancy achieving it. The diet could be a promising approach to enhance fertility.

15 Sep 2024

Researchers propose ketogenic diet as a novel treatment for anorexia nervosa

Research identifies a neurobiological model supporting a ketogenic diet as a therapeutic approach for anorexia nervosa, addressing both metabolic and psychological factors.

9 Sep 2024

Dietary patterns like fasting and the Mediterranean diet unlock molecular secrets to healthy aging

Study reviews the molecular mechanisms by which caloric restriction, intermittent fasting, the Mediterranean diet, and the ketogenic diet promote healthy aging.

2 Sep 2024