Ketogenic Diet News and Research

Latest Ketogenic Diet News and Research

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025

Study shows how ketogenic eating improves hormonal balance in PCOS

The very low-carbohydrate ketogenic diet leads to meaningful reductions in weight, visceral adiposity, insulin resistance, and androgen excess in women with PCOS based on pooled randomized trials. Benefits appear consistent across studies, though high heterogeneity, short durations, and limited safety data highlight the need for longer-term comparative research.

19 Nov 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Ketogenic diet protects young rats from effects of prenatal stress

Researchers have shown that young rats fed a ketogenic diet – a diet with high fat and low carbohydrates – are protected from the lasting experience of pre-natal stress.

12 Oct 2025

Keto diet reduces depression symptoms by 70% in college students

Research indicates a ketogenic diet may serve as an effective adjunct therapy for major depression in college students, improving mood and cognitive abilities.

15 Sep 2025

Ketogenic diets may lower migraine frequency and medication use

This narrative review argues that the migraine brain is hypometabolic, with converging evidence of mitochondrial dysfunction, impaired glucose handling, neuroinflammation, microbiome shifts, and obesity-related pathways. It proposes ketogenic diets as a plausible preventive strategy that may reduce monthly migraine days and medication use, while emphasizing the need for larger, rigorous randomized trials and careful clinical oversight.

14 Sep 2025

Ketogenic diet shows promise in reducing depression symptoms in college students

A new study shows an association between at least 10 weeks of following a well-formulated ketogenic diet and a roughly 70% decrease in depression symptoms among a small group of college students.

9 Sep 2025

New insights into how keto diet can restore cognitive function following status epilepticus

Epilepsy affects over 70 million people worldwide, and a significant portion of patients suffer from drug-resistant epilepsy (DRE), where standard medications fail.

11 Aug 2025

Personalizing endometrial cancer prevention through diet and lifestyle

This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.

7 Aug 2025

Fad diets and supplements fuel new wave of hidden skin problems, study finds

A new review explains how fad diets and unregulated supplements promoted online can cause serious skin, hair, and nail problems, often before other symptoms appear. Clinicians are urged to recognize these risks and address health misinformation in the digital age.

22 Jul 2025

Men lose more weight than women on the keto diet, new study reveals why

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex differences in hormones, metabolism, and fat distribution influence the effectiveness of the ketogenic diet for obesity.

22 Jun 2025

Back-to-basics, 'not fad' diets beat heart disease and diabetes

This review examines dietary interventions that can improve cardiometabolic health, highlighting the role of whole foods in reducing heart disease and diabetes.

4 Jun 2025

How soy and gut microbes alter cancer treatment results

Researchers have discovered that plant-derived phytochemicals and their gut microbiome metabolites control the effectiveness of PI3K inhibitors in cancer therapy. The study reveals that dietary components, especially soy compounds processed by gut bacteria, can alter drug metabolism and impact treatment outcomes.

2 Jun 2025

Which diet lowers blood pressure more: keto or Mediterranean?

A pilot study comparing a low-calorie, high-protein ketogenic diet and a Mediterranean diet in overweight and obese adults with elevated blood pressure found that both diets led to significant weight loss, improved body composition, and reduced blood pressure. Both dietary approaches were safe and well-tolerated, but the Mediterranean diet group showed a greater proportion of participants with healthy nocturnal blood pressure dipping.

26 May 2025

What really causes keto flu, and how can you prevent it?

A scoping review from the University of Bergen identifies a wide range of transient symptoms—collectively known as "keto flu"—that occur during the initiation of a ketogenic diet. The review explores their physiological basis and highlights strategies, such as MCTs and electrolyte supplementation, to ease the transition.

13 Apr 2025

High cholesterol may not signal heart disease risk in metabolically healthy people

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, in collaboration with researchers across multiple institutions, has published a new study that challenges the long-held belief that high cholesterol correlates and even directly causes coronary artery disease, or plaque buildup in the arteries in metabolically healthy individuals.

7 Apr 2025

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity speeds up biological aging at the molecular level, but this study finds that a very-low-calorie ketogenic diet (VLCKD) can significantly reverse this effect.

24 Mar 2025

Could a keto diet replace diabetes meds? New research explores the possibilities

A review published in Nutrients finds that ketogenic diets (KD) may offer superior benefits for weight loss, blood sugar control, and inflammation compared to other diets. Researchers also highlight potential mental health improvements but call for more clinical trials.

11 Mar 2025

UCLA Health launches study on ketogenic diet for bipolar disorder in youth

UCLA Health is set to begin a multi-site pilot study to explore whether a ketogenic diet, when combined with mood stabilizing medications, helps stabilize mood symptoms in teenagers and young adults who have bipolar disorder.

8 Feb 2025

How lifestyle-based interventions help manage PCOS

Studies indicate that lifestyle modifications can alleviate PCOS symptoms, improving insulin resistance and hormonal balance through diet and physical activity.

21 Jan 2025