Lung Cancer News and Research

Latest Lung Cancer News and Research

RAL proteins linked with aggressive cancer characteristics in human tumors

We have known for years that when the proteins RalA and RalB are present, cells in dishes copy toward aggressive forms of cancer. However, until this week, no study had explored the effects of RAL proteins in human cancers - an essential step on the path to developing drugs to target these proteins.

18 May 2012

CHOP researcher leads trial of ALK inhibitor in neuroblastoma, lymphoma

A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.

17 May 2012

First trial to investigate new drug combination for NSCLC

Cancer Research UK's Drug Development Office has opened the first trial of a new drug combination in patients with advanced solid tumours and in a subset of patients who have non-small cell lung cancer. This trial will combine two compounds that aim to starve the tumours while simultaneously blocking cancer cell growth.

17 May 2012

Data from Jennerex JX-594 clinical trials on cancer to be presented at ASCO annual meeting

Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic virus products for cancer, today announced that data relating to the company's oncolytic virus therapy for cancer will be covered in three separate abstracts released today by the American Society of Clinical Oncology.

17 May 2012

Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC

Boehringer Ingelheim will present results from LUX-Lung 3, the company's pivotal Phase III clinical trial investigating afatinib in patients with stage IIIB or IV non-small cell lung cancer (NSCLC) harboring an epidermal growth factor receptor (EGFR) mutation (EGFR M+), at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, June 1-5, 2012.

17 May 2012

Molecular biomarkers in the lungs may be an additional predictive technique for cancer screening

The most recent research released in June's Journal of Thoracic Oncology says molecular biomarkers in the tissue and fluid lining the lungs might be an additional predictive technique for lung cancer screening.

16 May 2012

Better understanding of new T-size descriptors on adjuvant chemotherapy effect needed

The most recent research released in June's Journal of Thoracic Oncology indicates there might be a positive correlation between tumor size and adjuvant platinum based chemotherapy in surgically resected patients with node negative non-small cell lung cancer.

16 May 2012

VATS plays a valuable role in lung cancer screening program

The most recent research released in June's Journal of Thoracic Oncology says video assisted thoracic surgery (VATS) is a valuable tool in managing lesions detected in a lung cancer screening program.

16 May 2012

Combination of vaccine and letrozole effectively improves survival from breast cancer

A vaccine that targets cancer cells in combination with the drug letrozole, a standard hormonal therapy against breast cancer, significantly increased survival when tested in mice, a team of UC Davis investigators has found.

16 May 2012

Viewpoints: Approving drugs quickly; Berwick: In health care, cheaper can mean better; Health costs 'persistent' concern

For about 20 years, the Food and Drug Administration (FDA) has charged pharmaceutical companies "user fees" for reviewing drug-approval applications. The revenue allows the FDA to hire more evaluators, which allows useful drugs to reach patients faster. Now the Prescription Drug User Fee Act needs reauthorization, as it does every five years. Legislators should not dillydally.

15 May 2012

Lilly to present oncology data from more than 25 studies at ASCO annual meeting

Eli Lilly and Company will present data from more than 25 studies at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Ill. from June 1 – 5, 2012, including overall survival results from PARAMOUNT, a Phase III study of an ALIMTA (pemetrexed for injection)-based continuation maintenance regimen for the treatment of advanced nonsquamous non-small cell lung cancer.

15 May 2012

Lung cancer molecular subtypes correlate with genetic alterations, patient's response to therapy

Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient's response to therapy.

14 May 2012

New discovery platform for antigen-specific monoclonal antibodies

Cell Signaling Technology, Inc. of Danvers, MA is pleased to announce the development of a new discovery platform for antigen-specific monoclonal antibodies.

From Cell Signaling Technology 11 May 2012

Citywide ban on public smoking can impact maternal and fetal health

A citywide ban on public smoking in Colorado led to significant decreases in maternal smoking and preterm births, providing the first evidence in the U.S. that such interventions can impact maternal and fetal health, according to an article in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

11 May 2012

Fast track approval process for “breakthrough” drugs proposed in the U.S.

Some experimental drugs that show a big effect early in development for treating serious or life-threatening diseases could soon get a faster and cheaper path to U.S. approval, under a proposal likely to become law this year.

10 May 2012

Botanical formula inhibits breast to lung cancer metastasis in mice

Scientists at Indiana University Health's Cancer Research Laboratory have found that a sophisticated botanical formula slows human breast cancer growth and inhibits breast to lung metastasis in mice. The formula contains extracts from medicinal mushrooms, medicinal herbs and purified nutritional compounds, and showed no toxic side-effects.

9 May 2012

Many unaware that persistent cough could be a warning for lung cancer

Most people are aware that that a lump in the breast is a warning sign of breast cancer and bleeding could indicate bowel, kidney or bladder cancer. However, only one in ten people knows that a persistent cough could point to lung cancer.

8 May 2012

Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting

Idera Pharmaceuticals, Inc. today announced data from preclinical studies of IMO-8400, demonstrating a novel mechanism of action that may be applicable to the treatment of systemic lupus erythematosus (SLE) and psoriasis. IMO-8400 is an inhibitor of specific Toll-like receptors (TLRs).

7 May 2012

PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Lung cancer is the leading cause of cancer death throughout the world. Standard treatment methods do not usually result in long-term recovery. In addition to the proliferation of the tumour cells, the growth of blood vessels controls tumors development. The blood vessel growth is controlled by several signalling molecules. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Justus Liebig University Giessen have discovered a molecule that plays a key role in this process. They succeeded in reducing tumour growth in their experiments by blocking the phosphodiesterase PDE4.

5 May 2012

Improved lung-cancer screening by combining blood test with CT imaging

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

4 May 2012

Lung Cancer News and Research

Latest Lung Cancer News and Research

RAL proteins linked with aggressive cancer characteristics in human tumors

CHOP researcher leads trial of ALK inhibitor in neuroblastoma, lymphoma

First trial to investigate new drug combination for NSCLC

Data from Jennerex JX-594 clinical trials on cancer to be presented at ASCO annual meeting

Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC

Molecular biomarkers in the lungs may be an additional predictive technique for cancer screening

Better understanding of new T-size descriptors on adjuvant chemotherapy effect needed

VATS plays a valuable role in lung cancer screening program

Combination of vaccine and letrozole effectively improves survival from breast cancer

Viewpoints: Approving drugs quickly; Berwick: In health care, cheaper can mean better; Health costs 'persistent' concern

Lilly to present oncology data from more than 25 studies at ASCO annual meeting

Lung cancer molecular subtypes correlate with genetic alterations, patient's response to therapy

New discovery platform for antigen-specific monoclonal antibodies

Citywide ban on public smoking can impact maternal and fetal health

Fast track approval process for “breakthrough” drugs proposed in the U.S.

Botanical formula inhibits breast to lung cancer metastasis in mice

Many unaware that persistent cough could be a warning for lung cancer

Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting

PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Improved lung-cancer screening by combining blood test with CT imaging

The ultimate guide to lung research tools and protocols eBook

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Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

Lung Cancer News and Research

Latest Lung Cancer News and Research

The ultimate guide to lung research tools and protocols eBook

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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